A5052041372- Selenium in Biological Systems
- Nanoparticles: synthesis and applications
- Moringa oleifera research and applications
- Human Health and Disease
- Bee Products Chemical Analysis
- Scientific Research and Studies
- Nanoparticle-Based Drug Delivery
- Anesthesia and Neurotoxicity Research
- Agriculture and Biological Studies
- Probiotics and Fermented Foods
- Pediatric health and respiratory diseases
- Animal Nutrition and Health
- Medical and Biological Ozone Research
- Food Industry and Aquatic Biology
- Gut microbiota and health
- Radiomics and Machine Learning in Medical Imaging
- Laser-Ablation Synthesis of Nanoparticles
- Antimicrobial Peptides and Activities
- Healthcare Systems and Public Health
- Free Radicals and Antioxidants
- Pesticide Exposure and Toxicity
- Insect and Arachnid Ecology and Behavior
- Immune Response and Inflammation
- Glutathione Transferases and Polymorphisms
- Gold and Silver Nanoparticles Synthesis and Applications
Danylo Zabolotny Institute of Microbiology and Virology
2013-2024
Bila Tserkva National Agrarian University
2021
National Academy of Sciences of Ukraine
2014
In recent decades, the attention of scientists has been drawn towards nanoparticles (NPs) metals and metalloids. Traditional methods for manufacturing NPs are now being extensively studied. However, disadvantages such as use toxic agents high energy consumption associated with chemical physical processes impede their continued in various fields. this article, we analyse relevance living systems components development "green" synthesis nano-objects exceptional properties a wide range...
Nanoscale gold particles (AuNPs) have wide perspectives for biomedical applications because of their unique biological properties, as antioxidative activity and potentials drug delivery.The aim was to test effects AuNPs using suggested heart failure rat model compare with proved medication Simdax, nanoparticle delivery, sonoporation effect increase nanoparticles delivery into myocardial cells.We performed biosafety biocompatibility tests conjugate Simdax. For in vivo tests, we included...
The biogenic method of nanoparticle synthesis with the participation microorganisms that are capable producing nanomaterials different shapes, sizes, and chemical compositions is a promising innovative direction nanotechnology. Bacteria chosen for production nanoparticles due to their rapid reproduction, ease cultivation, low energy requirements, minimal costs. complex synthetic mechanisms available allow them use large number building blocks construct new biosynthetic nanostructures can...
Abstract The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology. review demonstrates wide opportunities nanoparticles due to their unique biological properties. use cardiology is promising develop fundamentally new methods diagnosis treatment. nanotheranostics cardiovascular diseases allows non-invasive imaging associated with simultaneous therapeutic intervention predicting treatment...
A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good 1 % wealthy, not 99 unhealthy Andrews A5 The role IDO a...
The presented analytical review summarizes the data of world and national literature on features accumulation microelement nanoparticles in body, their effects metabolism, redox processes productivity poultry. attention is paid to toxicity various forms sources considered elements, mutual influence bioavailability, antagonism rate excretion. need study peculiarities use efficiency production livestock products constantly increasing. Evidence positive application nanoforms elements (zinc,...
The present study was performed to characterize of selenium nanoparticles (Nano-Se) which were synthesized by pulsed laser ablation in liquids obtain the aqueous citrate solution. conducted using bacteriological and electronic-microscopic methods. Transmission electron microscopy (TEM) spectroscopy analyses demonstrated that nano-selenium particles obtained method had size 4–8 nm. UV-Visible Spectrum colloidal solution Nano-Se exhibited absorption maxima at 210 To clarify some effects action...
The article is devoted to the mechanisms of regulation redox processes in cells, a review Keap1 / Nrf2 ARE redox-sensitive signaling system as fundamental pathway that plays key role maintaining cellular homeostasis under stressful, inflammatory, carcinogenic and proapoptotic conditions. structure cysteine-rich repressor protein Keap1, which responsible for sensory perception electrophiles reactive oxygen species, functions transcription factor Nrf2, activation through system, regulates...
Modern industrial poultry farming occupies a leading position in the production of dietary foods, for which it is appropriate to use biologically active substances and probiotics. The study compared effectiveness compound feed with addition sodium selenite, bio-nano-selenium L. plantarum terms body weight, weight gain, consumption safety experimental quail. quails Pharaoh meat breed were kept vivarium Bila Tserkva National Agrarian University by method analogues divided into 4 groups -...
The ability probiotics, affect the relevant Toll-like receptors (TLRs), can promote effective immune response and initiation of an defense. Gram positive bacteria formation T-and B-cell by altering products primarily IFN-g IL-12 are required for differentiation T helper cells into Th1 subpopulation direction. But probiotic preparations capable activating both (Th1 Th2) lymphocyte subpopulations, which provides a balance cytokine production. Immunomodulatory activity most important to...
Низка процесів, зокрема дія на організм важких металів, виснажують антиоксидантний захист, який при неправильному регулюванні може викликати окислювальний стрес, порушення енергетичних процесів у клітинах, приводячи до пошкодження важливих біомолекул, ДНК, білків та ліпідів. У роботі вивчалися особливості перебігу пероксидного окиснення ліпідів, активності ферментів антиоксидантного захисту енергетичного обміну крові, печінці нирках перепелів за моделювання кадмієвого навантаження корекції...
В останні десятиріччя увага науковців прикута до наночастинок металів та металоїдів (НЧ). Традиційні методи виготовлення НЧ нині інтенсивно вивчені. Проте недоліки, такі як використання токсичних агентів і високе споживання енергії, пов'язані з хімічними фізичними процесами, перешкоджають їх подальшому застосуванню в різних галузях. Проаналізовано актуальність живих систем компонентів для розробки технологій «зеленого» синтезу нанооб’єктів із винятковими властивостями широким спектром...
Green synthesis of nanoparticles (NPs) using living cells is a promising and new tool in bionanotechnology. Chemical physical methods are used to synthesize NPs, but biological preferred because their environmentally friendly, clean, safe, cost-effective, simple, efficient sources for high productivity purity. Aim. To investigate the processes bioreduction selenite ions into nanoselenium by probiotic strains lactobacilli Lactobacillus plantarum IMV B-7679 L. casei B-7280. Methods....
Traditional selenium supplements are usually highly toxic and have low levels of absorption, so developing systems that using compounds as a carrier to increase the bioavailability element control its release in body is extremely important. Nano-sized great interest dietary supplement, especially selenium-deficient states, well therapeutic agent without significant adverse effects. Emphasis placed on incorporation nanotechnologi cal applications, study an effective route administration,...
In the context of modern industrialisation poultry farming and growing global demand for quail products, fnding effective ways to improve bird productivity health is extremely important. One most promising approaches use nanoselenium bio-compounds with probiotics metabolic parameters quail. Recent research has focused on synthesis selenium nanoparticles using as an environmentally friendly alternative traditional methods adding inorganic feed. The advantage this approach production a...
Probiotics based on bacteria of the genus Bacillus with a multifactorial mechanism action are considered as possible alternative to antibiotics in treatment purulent wounds. The aim study was determine antimicrobial and therapeutic effect Arederma probiotic preparation containing strains an experimental model wound animals. efficacy against test clinical isolates pathogenic opportunistic microorganisms studied using method delayed antagonism. Staphylococcus aureus ATCC 6538 Streptococcus...
The aim of this work was to investigate the toxicity selenium preparations and probiotic by intragastric administration laboratory animals, weight coefficients internal organs white rats, haematological parameters rat blood on 30th day experiment. During experiment, 3 groups rats were formed, which received sodium selenite with bionanoselenium for a month at doses fed compound 1000, 3000 5000 mg/kg. We took into account such indicators animals as appearance, behavior, condition hair, visible...
It was demonstrated the wide potential for biomedical applications of nanoscale gold particles because their unique biological properties [1,2]. The use nanoparticles in cardiology is promising to develop fundamentally new methods diagnosis and treatment.
Recently, there has been a trend toward the use of new effective natural preparations to fight diseases and improve health honey bees. It is also known that well-balanced structure intestinal microbiota bees basis for their growth, development, strengthening immune response, resistance infections. established some strains lactic acid bacteria have antibacterial, anti-inflammatory, immunomodulatory properties, are promising development broad-spectrum probiotic based on them. Therefore, aim...
Selenium, as an important trace element, is part of selenoproteins with growth-modulating properties and multifactorial mechanisms action. The biological effects Se depend on the dose chemical form in which it enters body. Selenium nanoparticles have unique characteristics, including small size, large surface area, solubility multifunctionality. inclusion phytonutrient-functionalized feed expedient due to solubility, protection against oxidation enzymatic degradation, increased residence...