A5100744444- Systemic Lupus Erythematosus Research
- Mesenchymal stem cell research
- Sleep and Wakefulness Research
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Prostate Cancer Treatment and Research
- Hematopoietic Stem Cell Transplantation
- Cancer-related molecular mechanisms research
- Exercise and Physiological Responses
- T-cell and B-cell Immunology
- Adipose Tissue and Metabolism
- Digestive system and related health
- Muscle metabolism and nutrition
- Neuroscience and Neuropharmacology Research
- Immune Cell Function and Interaction
- MicroRNA in disease regulation
- Venous Thromboembolism Diagnosis and Management
- Galectins and Cancer Biology
- Neonatal Respiratory Health Research
- Ferroptosis and cancer prognosis
- Atherosclerosis and Cardiovascular Diseases
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Renal Diseases and Glomerulopathies
- Cancer Diagnosis and Treatment
Zhangjiakou Academy of Agricultural Sciences
2024
Shanghai Medical College of Fudan University
2018-2023
Zhongshan Hospital
2023
State Key Laboratory of Medical Neurobiology
2023
Qingdao University
2019-2022
Affiliated Hospital of Qingdao University
2019-2022
Fraternal Order of Eagles
2020-2021
University of Iowa
2021
First Affiliated Hospital of Jinan University
2019
Cell Technology (China)
2018-2019
We, the Editors and Publisher of journal Artificial Cells, Nanomedicine, Biotechnology, have retracted following article:Tao Chen, Shixiu Shao, Wenxian Li, Yong Liu & Yanwei Cao (2019) The circular RNA hsa-circ-0072309 plays anti-tumour roles by sponging miR-100 through deactivation PI3K/AKT mTOR pathways in renal carcinoma cell lines. 47(1), 3638–3648, DOI: 10.1080/21691401.2019.1657873Since publication, concerns been raised about integrity data article. When approached for an explanation,...
The physiological approach suggests that an environment associating mesenchymal stromal cells with low O2 concentration would be most favorable for the maintenance of hematopoietic stem/progenitor (HSPCs). To test this hypothesis, we performed a coculture cord blood CD34+ Wharton's jelly stem (WJ-MSCs) under different to simulate growth HSPCs in vivo, and assessed impacts on stemness proliferation vitro. derived from were isolated cocultured 1%, 3%, or 20% concentrations irradiated WJ-MSCs...
Brown adipose tissue (BAT) thermogenic activity is tightly regulated by cellular redox status, but the underlying molecular mechanisms are incompletely understood. Protein S-nitrosylation, nitric-oxide-mediated cysteine thiol protein modification, plays important roles in regulation. Here we show that diet-induced obesity (DIO) and acute cold exposure elevate BAT including UCP1. This thermogenic-induced nitric oxide bioactivity S-nitrosoglutathione reductase (GSNOR; alcohol dehydrogenase 5...
Podocyte apoptosis plays a vital role in proteinuria pathogenesis diabetic nephropathy (DN). The regulatory relationship between long noncoding RNAs (lncRNAs) and podocyte has recently become another research hot spot the DN field.
The incidence of colorectal cancer is on the increase owing to changes in daily diet. In present study, methylation status caudal type homeobox transcription factor 2 (CDX2) gene lesion tissue (CRC) was investigated. Additionally, correlation between promoter CDX2 gene, CRC and expression patients with normal population examined. Between April 2014 May 2015 78 cases were enrolled study. Using methylation-specific polymerase chain reaction (PCR), tissues examinned. Through fluorescence...
Lidocaine displays antitumor activity by inducing apoptosis and suppressing tumor growth in human hepatocellular carcinoma (HepG2) cells vitro. However, the molecular mechanism underlying lidocaine-mediated is unclear. In this study, HepG2 were treated with lidocaine, cell proliferation colony-forming ability assessed. The expression level of cytoplasmic polyadenylation element binding protein 3 (CPEB3) was detected real-time quantitative PCR western blot. treatment resulted decreased...
Abstract Background The umbilical cord blood (UCB) has been widely accepted as an alternative source of hematopoietic stem/progenitor cells (HSPCs) for transplantation, and its use in adults is still restricted because low absolute numbers. To overcome this obstacle, expansion UCB-HSPCs under feeder cell-based coculture a promising possibility. In study, we explored UCB-CD34+ ex vivo using Wharton’s jelly mesenchymal stem (WJ-MSCs) or vein endothelial (UVECs) layer-based serum-free system...
The aim of the present study was to examine diagnosis methylation CDX2 gene promoter in colorectal cancer (CRC) and assessed its value prediction treatment efficacy. Sixty patients who were diagnosed as CRCs for first time, 60 with hyperplastic polyps (HPs) adenomas, inflammatory lesions or healthy (control group) included study. levels detected by methylation-specific polymerase chain reaction (MSP), expression mRNA fluorescence quantitative PCR. Treatment options, such surgery,...
To investigate the pathological risk of prostate cancer (PCa) according to obesity and metabolic status Chinese patients undergoing radical prostatectomy.We performed a retrospective cross-sectional study 1016 with PCa who underwent prostatectomy whose body mass index were examined. Multivariate logistic regression analysis was examine relationship between different phenotypes outcomes PCa.Among men, 551 (54.2%), 106 (10.4%), 238 (23.4%), 121 (11.9%) assigned metabolically healthy normal...
This study aimed to identify critical cell cycle-related genes (CCRGs) in prostate cancer (PRAD) and evaluate the clinical prognostic value of gene panel selected. Gene set variation analysis (GSVA) dysregulated between PRAD normal tissues demonstrated that pathways played vital roles PRAD. Patients were classified into four clusters, which associated with recurrence-free survival (RFS). Moreover, 200 prognostic-related selected using Kaplan–Meier (KM) univariable Cox regression. The CCRG...
Background: The risk of secondary malignancies in prostate cancer (Pca) after radiation therapy (RT) is a controversial issue. This study compares RT, radical prostatectomy (RP), and no active treatment low-grade, organ-confined, Pca survivors who have life expectancy greater than 10-year. Methods: A retrospective was carried out large-scale cohort. compared 234,349 eligible patients aged ≤75 years using propensity-score matched competing-risk analysis. Results: In total, 87,913 (37.5%)...