- Synthesis and biological activity
- Metal-Organic Frameworks: Synthesis and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Crystal structures of chemical compounds
- Molecular Sensors and Ion Detection
- Synthesis and Biological Evaluation
- Multicomponent Synthesis of Heterocycles
- Advanced Nanomaterials in Catalysis
- Synthesis of heterocyclic compounds
- Synthesis and Reactions of Organic Compounds
- Synthesis and Reactivity of Heterocycles
- Enzyme Production and Characterization
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Endodontics and Root Canal Treatments
- Luminescence and Fluorescent Materials
- Phenothiazines and Benzothiazines Synthesis and Activities
- Asymmetric Synthesis and Catalysis
- Gas Sensing Nanomaterials and Sensors
- Bioactive Compounds and Antitumor Agents
- Synthesis and Catalytic Reactions
- Phytase and its Applications
- Cyclopropane Reaction Mechanisms
- Oxidative Organic Chemistry Reactions
- Quinazolinone synthesis and applications
- Phytoestrogen effects and research
University of Manitoba
2025
Punjabi University
2014-2024
Guru Nanak Dev University
2024
University of Jammu
2024
Panjab University
2021-2024
Maharishi Markandeshwar University, Mullana
2023-2024
Chandigarh University
2024
Bridge University
2022-2023
Keene State College
2016-2022
DAV University
2021
Abstract The study was conducted to analyze the antimicrobial activity and sensitivity of bovine lactoferrin against foodborne pathogens evaluate pH range thermal stability lactoferrin. agar well diffusion test used check each pathogen. Bacterial samples were purified confirmed by biochemical tests. Three concentrations 0.5, 1, 10 mg/ml evaluated for antibacterial Escherichia coli, Salmonella enteritidis, Staphylococcus aureus. Our results indicated that all three pathogenic bacteria...
Keratinases hydrolyze structural protein called keratin into constituent peptides. The present study reports excellent washing efficiency and dehairing properties of thermostable halotolerant keratinase from Bacillus aerius NSMk2. Alkaline with molecular mass 9 kDa displayed remarkable thermostability. K+ , Na+ Ca2+ Mn2+ β-mercaptoethanol, sodium sulfite, dithiothreitol, ethanol, isopropanol, Tween-20, Tween-80 stimulated activity, while Hg2+ Ba2+ were found to be inhibitory. enzyme...
A method for pot and atom economic synthesis of polycyclic spirooxindoles through α-C–H functionalization cyclic amines has been developed. This highly efficient three-component [3+2] cycloaddition reaction was catalyzed by recyclable montmorillonite K10 only water produced as a byproduct.
Sequential inter- and intramolecular [3 + 2] cycloadditions of azomethine ylides are developed for the one-pot diastereoselective synthesis highly condensed heterocyclic systems containing pyrrolidine up to seven stereocenters. It has high synthetic efficiency operational simplicity, only water was generated as a byproduct.
Nonstabilized azomethine ylides derived from decarboxylation of oxazolidin-5-ones were used for double 1,3-dipolar cycloadditions in diastereoselective synthesis pyrrolidine-containing tetracyclic compounds. This is the first example one-pot and five-component reactions involving two nonstabilized ylides. Only CO2 water generated as byproducts.
The interest in the present study pertains to development of a new compound based upon benzimidazole thiourea moiety that has unique properties related elastase inhibition, free radical scavenging activity and its DNA binding ability. title compound, N-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-3-benzoyl (C21H18N4O2SH2O:TUBC), was synthesized by reacting an acid chloride benzoic with potassium thiocyanate (KSCN) along subsequent addition 4-(1H-benzo[d]imidazol-2-yl)benzenamine via one-pot...
An atom economic and facile synthesis of novel dispiro–oxindole–pyrrolidines has been achieved via a three‐component tandem cycloaddition azomethine ylide generated in situ from isatin sarcosine by decarboxylative condensation with N ‐aryl‐3‐benzylidene‐pyrrolidine‐2,5‐dione derivatives as dipolarophiles. The salient features synthetic procedure are characterized the mild reaction conditions, high yields, regioselectivity stereoselectivity, one‐pot procedure, operational simplicity. This was...
1,3-Dipolar cycloaddition of nonstabilized azomethine ylides derived from α-C-H functionalization tetrahydroisoquinoline for regio- and diastereoselective synthesis spirooxindole-pyrrolidines is developed. A three-component reaction readily available cyclic amine, aryl aldehydes, olefinic oxindoles provides a pot, atom step economy (PASE) approach making spiro-heterocyclic compounds with biological interest.
The antioxidant activity of isatin derivatives can be described with the presence enolic hydroxyl group at second position ring because keto‐enol tautomerism between NH and CO groups indolone moiety. reducing ability tested compounds was evaluated by their interaction stable free radical 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) various concentrations. Novel spiro[oxindole‐isoxazolidine] ( 4a , 4b 4c 4d 4e 4f 4g 4h 4i ) have been synthesized 1,3‐dipolar cycloaddition reactions variously...
Abstract Keratinase is a robust enzyme that produced in the presence of keratin substrates. This has been recognized for its applications waste management, leather and detergent industries. Our group isolated potential keratinase producing strain Bacillus aerius NSMk2 from poultry dump soil, hide dehairing stain removal have studied. Considering commercial applicability keratinase, present study reports production stirred tank reactor (5 l). Central composite rotatable design response...