Up the tempo: The intramolecular addition of oxime radicals to CC bonds was achieved by using DEAD and TEMPO give 4,5-dihydroisoxazoles as a result CO bond-forming, 5-exo-trig cyclization. γ,δ-Unsaturated ketoximes also reacted afford cyclic nitrones through CN bond formation. reactions offer metal-free approach for vicinal difunctionalization unactivated alkenes. Detailed facts importance specialist readers are published "Supporting Information". Such documents peer-reviewed, but not...

A new Ag/Brønsted acid co-catalyzed spiroketalization of β-alkynyl ketones with para-quinone methides (p-QMs) has been established, enabling multiple C-C and C-O bond-forming events to access densely functionalized spiro[chromane-2,1'-isochromene] derivatives generally excellent diastereoselectivity good yields. reasonable mechanism for forming these 6,6-dibenzannulated spiroketals involving 6-endo-dig oxo-cyclization 1,6-addition-cyclization cascades is proposed.

An efficient alkoxyl radical-triggered ring expansion/cross-coupling cascade was developed under cheap metal catalysis. Through the metal-catalyzed radical relay strategy, a wide range of medium-sized lactones (9-11 membered) and macrolactones (12, 13, 15, 18, 19-membered) were constructed in moderate to good yields, along with diverse functional groups including CN, N3, SCN, X installed concurrently. Density theory (DFT) calculations revealed that reductive elimination cycloalkyl-Cu(iii)...

A concise Fe-catalyzed alkylazidation of α-trifluoromethylalkenes via a C–C bond cleavage/radical addition/azidation cascade is described. This protocol features broad substrate scope, excellent functional group compatibility, and the ability to be performed on gram scale, thus offering practical step-economic approach synthetically useful tertiary α-trifluoromethyl azides.

A redox-neutral copper-catalyzed cascade reaction involving alkoxyl radical-mediated ring expansion/1,4-difunctionalization of 1,3-enynes was developed, offering a straightforward approach to the tetra-substituted allenes with macrolactone, CN, and CF3 functional groups. Remarkably, incorporation NH2 group onto 1,3-enyne moiety enabled further cyclization give unique scaffold containing lactone an indole moiety.

Yttrium iron garnet (Y3Fe5O12, YIG) plays a significant role in the field of spintronics due to its low magnetic damping and insulating characteristics. However, most studies have focused on YIG bulk form or as film grown rigid substrates. In this study, has been exfoliated from two-layer-graphene covered (111) Gd3Ga5O12 (GGG) substrate. Magnetic properties under stress are investigated detail via angular dependent ferromagnetic resonance. The relationship between parameters...

Ferromagnetic insulating garnet films with perpendicular magnetic anisotropy (PMA) are of great importance for the applications in spintronics. Tm3Fe5O12 (TmIG) magnetoelastic has been proven to exhibit PMA more easily than Y3Fe5O12. Here, parameters TmIG various thicknesses investigated by ferromagnetic resonance. The relationship between effective magnetization, surface field, constants and film thickness is established. spin Hall angle, diffusion length, real part mixing conductance...

Here, we present an electrochemical C(sp2)-H bond alkylation from unactivated alkyl iodides via halogen-atom transfer (XAT) process under mild conditions. This strategy avoids the drawbacks associated with sacrificing reactive metal...

A visible-light-induced, energy-transfer mechanism for O2-initiated deboronative generation of alkyl radical approaches from alkylboronic acids and guided to a Smiles rearrangement reaction has been developed. This protocol utilizes tetracoordinate boron...

The combination of AgTFA and Sc(OTf)3 enables the bimetallic synergistic catalysis β-alkynyl ketones para-quinone methides (p-QMs), allowing direct synthesis 17 examples benzo[c]xanthenes with generally good yields through a benzannulation/1,6-addition/cyclization sequence. Exchanging p-QMs for quinone imine ketal resulted in 10 tetracyclic naphtho[1,2-b]benzofurans via similar benzannulation/1,4-addition/cyclization cascade. During these reaction processes, could be perfectly compatible,...

Switchable in situ SO2 capture and CF3 migration of enol triflates with peroxyl compounds under iron catalysis are presented. By regulating the structure peroxides, a variety keto-functionalized dialkyl sulfones α-trifluoromethyl ketones were selectively synthesized good yields mild conditions.

Dual-atom catalysts (DACs) have emerged as potential for effective electroreduction of CO2 due to their high atom utilization efficiency and multiple active sites. However, the screening DACs remains a challenge large number possible combinations, making exhaustive experimental or computational daunting task. In this study, density functional theory (DFT)-based machine learning (ML)-accelerated (DFT-ML) hybrid approach was developed test set 406 dual transition metal on N-doped graphene (NG)...

Abstract We reported herein a predictable and surgical cleavage of carbon‐carbon bond in alcohols. A wide range 1°, 2° 3° alcohols including sugars steroids without ring strain or steric hindrance were all compatible with this system. Also it offered green practical strategy for generation alkyl/acyl radicals using as the sources. Besides, features visible‐light‐initiation, catalyst metal free, excellent selectivity mild conditions make valuable attractive. magnified image

An intermolecular Dowd–Beckwith ring expansion/C–C bond formation is achieved through light-induced palladium catalysis. Not only styrenes but also the electron-rich alkenes such as silyl enol ethers and enamides were compatible in this reaction.

Since China's reform and opening-up in 1978, the income of rural residents has increased when compared with that urban residents. However, growth rate farmers is relatively low, gap between areas widening. Using a sample 1,325 large-scale farming households Lin'an, this study constructs theoretical path for how level vertical integration an organization model affect farmers' levels empirically tests using mediation effect analysis model. The results indicate models are important factors...

An inexpensive iron-catalyzed alkoxyl radical-induced C–C bond cleavage/gem-difluoroalkylation cascade is presented. Regulated by the structure of radical precursors, fluorinated distal diketones were synthesized through a ring-opening strategy and difluoroalkylated medium-sized lactones macrolactones constructed via ring-expansion strategy. Both protocols proceeded under mild redox neutral conditions with broad substrate scope good functional group compatibility.

The pot-economic synthesis of N, N'-diarylindazol-3-ones has been developed using readily available isatoic anhydrides, aryl amines, and boronic acids. A Cu-catalyzed oxidative C-N cross-coupling dehydrogenative N-N formation sequence under an air atmosphere affords indazol-3-one derivatives in good to excellent yields. Such process merges well with the preceding decarboxylative amination reaction, resulting a more modular straightforward approach.

Abstract New silver‐catalyzed tunable dimerization and trimerization reactions of β‐alkynyl ketones have been established, enabling multiple C−C bond‐forming events to selectively access skeletally diverse spiroisochromenes with generally good yields. The silver‐enabled bicycloaddition water offered hydroxylated spiroisochromenes. Without water, a methylene moiety were obtained through catalytic 6‐ endo‐dig oxo ‐cyclization/[4+2] cycloaddition cascades by using pyridine as additive whereas...

Chemoselective <italic>N</italic>-arylation of unprotected aminobenzamides was achieved <italic>via</italic> Cu-catalysed Chan–Evans–Lam cross-coupling with aryl boronic acids for the first time.

Chemoselective <italic>N</italic>-arylation of unprotected dinucleophilic aminobenzene sulfonamides was achieved <italic>via</italic> Cu-catalysed Chan–Evans–Lam cross-coupling with aryl boronic acids.

An efficient copper-catalyzed radical ring-opening halogenation with HX (aq) is described. This protocol provides a practical access to distally chlorinated, brominated and iodinated alkyl ketones nitriles moderate good yields.