A5046085342- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Cancer Treatment and Pharmacology
- Traditional Chinese Medicine Studies
- Ion channel regulation and function
- Nicotinic Acetylcholine Receptors Study
- Plant-based Medicinal Research
- Ginseng Biological Effects and Applications
- Phytochemistry and Biological Activities
- Metabolomics and Mass Spectrometry Studies
- Analytical chemistry methods development
- Acupuncture Treatment Research Studies
- Analytical Chemistry and Chromatography
- Synthetic Organic Chemistry Methods
- Bioactive Natural Diterpenoids Research
- Microbial Natural Products and Biosynthesis
- Neuroscience and Neuropharmacology Research
- Geochemistry and Elemental Analysis
- Pharmacogenetics and Drug Metabolism
- Essential Oils and Antimicrobial Activity
- Quinazolinone synthesis and applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Medical Research and Treatments
- Complementary and Alternative Medicine Studies
- Catalytic C–H Functionalization Methods
Northeast Forestry University
2008-2025
Chinese Academy of Agricultural Sciences
2015-2024
Chinese Academy of Tropical Agricultural Sciences
2013-2024
Beijing Technology and Business University
2024
Jiangsu University
2017-2024
Oil Crops Research Institute
2024
Weatherford College
2024
Tropical Crops Genetic Resources Institute
2013-2024
The University of Queensland
2017-2024
Ministry of Agriculture and Rural Affairs
2022-2024
Owing to the significant biological activities, quinazoline derivatives have drawn more and attention in synthesis bioactivities research. This review summarizes recent advances activities investigations of derivatives. According main method authors adopted their research design, those synthetic methods were divided into five classifications, including Aza-reaction, Microwave-assisted reaction, Metal-mediated Ultrasound-promoted reaction Phase-transfer catalysis reaction. The synthesized...
Objective St John's wort, an extract of the medicinal plant Hypericum perforatum , is widely used as herbal antidepressant. Although ability wort to induce cytochrome P450 (CYP) 3A4–mediated reaction has been well established, effect on CYP2C19 still not determined. Thus objective this study was determine impact pharmacokinetic profiles omeprazole and its metabolites. Methods Twelve healthy adult men (6 CYP2C19*1 / 4 CYP2C19*2 2 CYP2C19*3 ) were enrolled in a 2‐phase randomized crossover...
Abstract The Ediacaran–Cambrian transition was one of the most critical intervals in Earth history. During this interval, widespread chert precipitated, commonly as a stratal wedge carbonates, along southern margin Yangtze Platform, South China. passes into full succession further basinward to south‐east. Four lithotypes are identified across marginal zone western Hunan: mounded, vein, brecciated and bedded chert. mounded is characterized by irregular digitiform internal fabrics, generally...
Ten diterpenoid alkaloids, including eight aconitine-type C19-diterpenoid alkaloids and two hetisine-type C20-diterpenoid were isolated from the secondary roots of Aconitum carmichaeli Debx., known as “Fuzi” in Chinese traditional herbal medicine. Their structures established on basis their spectroscopic data comparison with those literature. Among these chasmanine, oxonitine 15-acetylsongoramine for first time this medicinal plant. The cytotoxic activity tested against several cell lines by...
Abstract Ecological restoration of mine tailings have impact on soil physiochemical properties and microbial communities. The surface has been a primary concern in the past decades, however it remains poorly understood about adaptive response communities along profile during ecological tailings. In this study, 60-cm were investigated tailing pond bare waste (BW) with two vegetated soils Imperata cylindrica (IC) Chrysopogon zizanioides (CZ) plants. Revegetation both IC CZ could retard...
Functional magnetic resonance imaging has been widely used to investigate the effects of acupuncture on neural activity. However, most functional studies have focused acute changes in brain activation induced by acupuncture. Thus, time course therapeutic remains unclear. In this study, 32 patients with amnestic mild cognitive impairment were randomly divided into two groups, where they received either Tiaoshen Yizhi or sham acupoint The needles twirled at acupoints, including Sishencong...
Oxaliplatin is a first-line clinical drug in cancer treatment and its side effects of peripheral neuropathic pain have also attracted much attention. Neuroinflammation induced by oxidative stress-mediated activation nuclear factor-kappa B (NF-κB) plays an important role the course. Current studies shown that curcumin has various biological activities like antioxidant, anti-inflammatory, antitumor so on, while few were conducted about oxaliplatin-induced pain. The aim this study to verify...
Abstract The accumulation of reactive oxygen species (ROS) is a widespread defence mechanism in higher plants against pathogen attack and sometimes the cause cell death that facilitates by necrotrophic pathogens. Plant pathogens use superoxide dismutase (SOD) to scavenge ROS derived from their own metabolism or generated host defence. significance roles SODs vascular plant Verticillium dahliae are unclear. Our previous study showed significant upregulation Cu/Zn‐SOD1 (VdSOD1) cotton tissues...
Rhododendron dauricum L. is one of the most important ornamental plants in Northeast China for its beautiful flowers. Wild R. populations are mainly distributed Greater and Lesser Khingan Mountains Heilongjiang, China. The diversity germplasm resources these areas has not been determined it can be dynamic due to increasing climate change human activities, which poses a challenge effective conservation efforts. To promote genetic develop new varieties, we performed systematic morphological...
The combination of AgTFA and Sc(OTf)3 enables the bimetallic synergistic catalysis β-alkynyl ketones para-quinone methides (p-QMs), allowing direct synthesis 17 examples benzo[c]xanthenes with generally good yields through a benzannulation/1,6-addition/cyclization sequence. Exchanging p-QMs for quinone imine ketal resulted in 10 tetracyclic naphtho[1,2-b]benzofurans via similar benzannulation/1,4-addition/cyclization cascade. During these reaction processes, could be perfectly compatible,...
To assess the effectiveness of violate oil from Blumea Balsamifera (L.) DC. leaves (BB oil) on wound healing in mice. Undiluted BB and its diluted solutions with olive to 1/5 1/10 yield oil1/5 oil1/10 were applied wounded skin before conditions assessed by rate, histopathology, contents collagen, hydroxyproline, Neuropeptide Substance P (SP). All above results compared efficacies control, pure oil, basic fibroblast growth factor (BFGF), cream Jing Wan Hong (JWH). improved contraction...
Our previous findings have demonstrated that acupuncture at the Taixi (KI3) acupoint in healthy youths can activate neurons cognitive-related cerebral cortex. Here, we investigated whether this elderly patients with mild cognitive impairment also these regions. Resting state and task-related functional magnetic resonance imaging showed pinprick senstation of differed significantly between controls. Results 20 brain regions were activated both groups participants, including bilateral anterior...