A5087600642- Neurobiology and Insect Physiology Research
- Circadian rhythm and melatonin
- Spaceflight effects on biology
- Innovation, Sustainability, Human-Machine Systems
- Virus-based gene therapy research
- Light effects on plants
- Epigenetics and DNA Methylation
- Climate Change Communication and Perception
- Physiological and biochemical adaptations
- Animal Genetics and Reproduction
- RNA Research and Splicing
- Advanced Optical Imaging Technologies
- Congenital heart defects research
- RNA modifications and cancer
- Semiconductor Lasers and Optical Devices
- Optical Wireless Communication Technologies
University of Vienna
2021-2023
Vienna Biocenter
2021-2023
Max Perutz Labs
2021-2023
Many species synchronize their physiology and behavior to specific hours. It is commonly assumed that sunlight acts as the main entrainment signal for ∼24-h clocks. However, moon provides similarly regular time information. Consistently, a growing number of studies have reported correlations between diel lunidian cycles. Yet, mechanistic insight into possible influences on timers remains scarce. We explored marine bristleworm Platynereis dumerilii investigate role moonlight in timing daily...
The moon's monthly cycle synchronizes reproduction in countless marine organisms. mass-spawning bristle worm Platynereis dumerilii uses an endogenous oscillator set by full moon to phase specific days. But how do organisms recognize phases? We uncover that the light receptor L-Cryptochrome (L-Cry) discriminates between different moonlight durations, as well sun- and moonlight. A biochemical characterization of purified L-Cry protein, exposed naturalistic or moonlight, reveals formation...
Access to newer, fast, and cheap sequencing techniques, particularly on the single-cell level, have made transcriptomic data of tissues or single cells accessible many researchers. As a consequence, there is an increased need for in situ visualization gene expression encoded proteins validate, localize, help interpret such data, as well put them context with cellular proliferation. A particular challenge labeling imaging transcripts are complex that often opaque and/or pigmented, preventing...
Science & Society2 February 2023Open Access Transparent process The paradox of the life sciences How to address climate change in lab Nikola Winter Corresponding Author [email protected] orcid.org/0000-0003-0107-1989 Max Perutz Labs, Department Biochemistry and Cell Biology, University Vienna, Austria (www.maxperutzlabs.ac.at/about/sustainability) Search for more papers by this author Raphaël Marchand orcid.org/0000-0002-3280-1078 Faculty Physics, Structural Computational Christian Lehmann...
Abstract The moon’s monthly cycle synchronizes reproduction in countless marine organisms. mass-spawning bristle worm Platynereis dumerilii uses an endogenous oscillator to phase specific days. Classical work showed that this is set by full moon. But how do organisms recognize such a moon phase? We uncover the light receptor L-Cryptochrome (L-Cry) able discriminate between different moonlight durations, as well sun- and moonlight. Consistent with L-Cry’s function valence interpreter, its...
Abstract Many species synchronize their physiology and behavior to specific hours. It is commonly assumed that sunlight acts as the main entrainment signal for ~24h clocks. However, moon provides similarly regular time information, increasingly studies report correlations between diel lunidian cycles. Yet, mechanistic insight into possible influences of on ~24hr timers scarce. We studied Platynereis dumerilii uncover moon, besides its role in monthly timing, also schedules exact hour...
Abstract Access to newer, fast and cheap sequencing techniques, particularly on the single-cell level, have made transcriptomic data of tissues or single cells accessible many researchers. As a consequence, there is increased need for in situ visualization gene expression encoded proteins validate, localize help interpret such data, as well put them context with cellular proliferation. A particular challenge labeling imaging transcripts are complex that often opaque and/or pigmented,...