Journal Article CLUMSY CHILDREN A STUDY OF APRAXIC AND AGNOSIC DEFECTS IN 21 Get access S. GUBBAY, GUBBAY From The Regional Neurological Centre, Newcastle General Hospital, Percy Hedley and Department of Child HealthUniversity upon Tyne Search for other works by this author on: Oxford Academic PubMed Google Scholar E. ELLIS, ELLIS J. N. WALTON, WALTON D. M. COURT Brain, Volume 88, Issue 2, June 1965, Pages 295–312, https://doi.org/10.1093/brain/88.2.295 Published: 01 1965

Journal Article CLUMSY CHILDREN: DEVELOPMENTAL APRAXIA AND AGNOSIA Get access J. N. WALTON, WALTON Search for other works by this author on: Oxford Academic PubMed Google Scholar E. ELLIS, ELLIS S. D. M. COURT Brain, Volume 85, Issue 3, September 1962, Pages 603–612, https://doi.org/10.1093/brain/85.3.603 Published: 01 1962

<h3>SUMMARY</h3> Mitochondria are increasingly recognized as cellular hubs to orchestrate signaling pathways that regulate metabolism, redox homeostasis, and cell fate decisions. Recent research revealed a role of mitochondria also in innate immune signaling, however, the mechanisms how affect signal transduction poorly understood. Here we show NF-ĸB pathway activated by TNF employs platform for amplification shuttling nucleus. induces recruitment HOIP, catalytic component linear ubiquitin...

In 1940 Noetzel reported two cases of slowly progressive neurological illness in which, at necropsy, the meninges overlying brain and spinal cord peripheral areas brain, cerebellum, were found to be rust-brown colour.

Posttraumatic stress disorder (PTSD) affects 5–10% percent of the US adult population with a higher prevalence among women compared men. Although it remains unclear how biological sex associates susceptibility to PTSD, one mechanism may involve role for estrogen in gene by environment interaction. We previously demonstrated sex-dependent association between pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) and where carriers C allele at single-nucleotide polymorphism...

Although it has been recognized for many years that symptoms and signs indicating disordered function of the voluntary musculature may be prominent in patients with myxoedema, muscular manifestations hypothyroidism have received comparatively little attention British litera- ture.Recent reviews have, however, given by Thomasen (1948), Piaggio Blancho Malosetti (

It has been recognized for many years that in patients with muscular dystrophy there are sub- stantial increases the activity of certain enzymes, e.g., aldolase and transaminases, serum.Extensive surveys by several workers have shown changes particularly striking cases Duchenne type (decreasing as disease progresses), smaller limb-girdle facio-scapulo-humeral types dystrophy, slight or absent neurogenic weakness wasting (Dreyfus Schapira, 1955;

Cystic fibrosis-related diabetes mellitus (CFRD) is the most frequent comorbidity in cystic fibrosis. Its clinical relevance stressed by association with increased mortality, and decreased pulmonary nutritional status. An annual oral glucose tolerance test (OGTT) recommended as a screening for CFRD, but this often not realised because of its time- resource-consuming nature. Therefore, alternative approaches are welcome. In 2003, American Diabetes Association (ADA) lowered cut-off point...

POLIOMYELITIS IN MAURITIUS BMEIt will be seen that Case 1 was already ill when the mother took child to fed.In 2 also there a suspicion whether really well just before vaccination.The grandfather of had died post-operatively in same house two weeks fell ill, and crowding for funeral.In Cases 3 4 careful inquiry did not.reveal any history illness vaccination.They were last cases outbreak.TABLE XI.-Cases Reported After Use Sabin Vaccine Age Date Feeding District Onset with years 21/8159...

It is generally recognized that many patients with spon taneous subarachnoid haemorrhage die in a first attack of bleeding. Walton (1952a) reports series 312 cases, 45% which succumbed the or recurrence bleeding during eight weeks illness. Until comparatively recently little infor mation has been available on fate who survive ; despite lack adequate data, some authors (Sands, 1941 Baumoel, 1941) have suggested recurrent after an interval rule. This somewhat gloomy conception outlook re...

Purpose Limited research focuses on the challenges that exist at intersection of race and dis/ability for Black men autism spectrum in encounters with law enforcement. An interdisciplinary approach is necessary to fully comprehend mitigate complex challenges. This conceptual article presents Critical Dis/ability (DisCrit) Theory, a framework usually applied education, as lens through which think about between autistic police officers. The concludes recommendations collaboration social...

Three cases of a painful, inflammatory, nodular myopathy in young and middle-aged adult males are described. In two the process gradually evolved into diffuse proximal accompanied by dysphagia, manifesting so-called ‘facioscapulohumeral syndrome’. The electromyogram (EMG) all three was ‘myopathic’ type abnormalities consistent with an inflammatory muscle disorder were seen. Muscle biopsy revealed pattern intense, predominantly interstitial, pleomorphic infiltration scattered foci fibre...

A double-blind cross-over trial over 24 weeks (10 on the active remedy, 4 off treatment, and 10 placebo) of effect L-dopa idiopathic Parkinsonism (paralysis agitans) has shown no difference in response obtained patients who had undergone previous stereotaxic ventrolateral thalamotomy those not. Of 34 (18 men 16 women) 18 been operated (nine unilateral, nine bilateral operations) All entering were taking anticholinergic drugs stable dosage these continued throughout. The only factor which...

The results are reported of a trial in which 34 patients receiving stable dose levodopa for the treatment idiopathic Parkinsonism, as well anticholinergic drugs they had been taking before introduction levodopa, underwent withdrawal their remedies. Withdrawal was gradual over four weeks 17 (group 1) and abrupt remaining 2). Only 11 out on therapy were able to tolerate more than eight weeks. main reasons resumption these remedies subjective increases slowness 20 (59%), tremor 15 (44%),...

In the true occipito-posterior position a deliberate face-to-pubes delivery with forceps is usually indicated when head low, and this has small foetal risk.