- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Stress Responses and Cortisol
- Helicobacter pylori-related gastroenterology studies
- Dark Matter and Cosmic Phenomena
- Neuroendocrine regulation and behavior
- Particle Detector Development and Performance
- Adipose Tissue and Metabolism
- Neuroscience and Neuropharmacology Research
- Eosinophilic Esophagitis
- Estrogen and related hormone effects
- Neurogenesis and neuroplasticity mechanisms
- Gastroesophageal reflux and treatments
- Distributed systems and fault tolerance
- Advanced Data Storage Technologies
- Tryptophan and brain disorders
- Computational Physics and Python Applications
- Retinoids in leukemia and cellular processes
- Neurotransmitter Receptor Influence on Behavior
- Particle Accelerators and Free-Electron Lasers
- Gastric Cancer Management and Outcomes
- Regulation of Appetite and Obesity
- Circadian rhythm and melatonin
- Heavy Metal Exposure and Toxicity
Rutgers, The State University of New Jersey
1989-2023
University of Science and Technology of China
2008-2023
Chinese Academy of Sciences
2020-2023
Hefei National Center for Physical Sciences at Nanoscale
2023
Center for Excellence in Brain Science and Intelligence Technology
2020
GeneTAG Technology (United States)
2016
Netherlands Institute for Neuroscience
2011-2013
University of Amsterdam
2011-2012
Sun Yat-sen University
1992-2009
The First Affiliated Hospital, Sun Yat-sen University
1992-2009
Journal Article Epidemiology of Helicobacter pylori in Southern China: Identification Early Childhood as the Critical Period for Acquisition Get access H.M. Mitchell, Mitchell Search other works by this author on: Oxford Academic PubMed Google Scholar Y.Y. Li, Li P.J. Hu, Hu Q. Liu, Liu M. Chen, Chen G.G. Du, Du Z.J. Wang, Wang A. Lee, Lee S.L. Hazell The Infectious Diseases, Volume 166, Issue 1, July 1992, Pages 149–153, https://doi.org/10.1093/infdis/166.1.149 Published: 01 1992 history...
We present measurements of the pseudorapidity (η) distribution charged particles (dNchdη) produced within |η|≤3.5 in proton-antiproton collisions at √s 630 and 1800 GeV. measure dNchdη η=0 to be 3.18±0.06(stat)±0.10(syst) GeV, 3.95±0.03 (stat)±0.13(syst) Many systematic errors ratio two energies cancel, we 1.26±0.01±0.04 for GeV that |η|≤3. Comparing lower-energy data, observe an increase faster than ln(s) η=0.Received 2 October 1989DOI:https://doi.org/10.1103/PhysRevD.41.2330©1990 American...
Measurements of inclusive transverse-momentum spectra for charged particles produced in proton-antiproton collisions at √2 630 and 1800 GeV are presented compared with data taken lower energies.Received 8 June 1988DOI:https://doi.org/10.1103/PhysRevLett.61.1819©1988 American Physical Society
Glucocorticoid receptor (GR) antagonism may be of considerable therapeutic value in stress-related psychopathology such as depression. However, blockade all GR-dependent processes the brain will lead to unnecessary and even counteractive effects, elevated endogenous cortisol levels. Selective GR modulators are ligands that can act both agonist antagonist used separate beneficial from harmful treatment effects. We have discovered high-affinity ligand C108297 is a selective modulator rat...
<b>Background:</b> Overexpression of cyclooxygenase 2 (COX-2) is frequently detected in gastric cancer and believed to play a crucial role carcinogenesis. <b>Aim:</b> We examined the chemopreventive effect COX-2 inhibitor an animal model stomach <b>Methods:</b> Eighty six male Wistar rats were divided into different treatment groups: group A, water alone (n = 5); B, <i>N</i>-methyl-<i>N′</i>-nitro-<i>N</i>-nitrosoguanidine (MNNG 100 μg/ml) 16); C, indomethacin (3 mg/kg/day) D, celecoxib (5...
A search for the top quark in p\ifmmode\bar\else\textasciimacron\fi{}p collisions at a center-of-mass energy of 1.8 TeV using Collider Detector Fermilab is described. study events selected by requiring an energetic electron, missing transverse energy, and two or more jets excludes 95% confidence level standard-model production decay tt\ifmmode\bar\else\textasciimacron\fi{} pairs if top-quark mass between 40 77 GeV/${c}^{2}$. The observed electron + multijet data are consistent with W-boson...
We have determined mW=79.91±0.39 GeV/c2 from an analysis of W→eν and W→μν data the Collider Detector at Fermilab in p¯p collisions a c.m. energy √s =1.8 TeV. This result, together with world-average Z mass, determines weak mixing angle to be sin2θW=0.232±0.008. Bounds on top-quark mass are discussed.Received 13 August 1990DOI:https://doi.org/10.1103/PhysRevLett.65.2243©1990 American Physical Society
The detailed population-based data on irritable bowel syndrome in South China are lacking.To assess the prevalence of and its impact health-related quality life.A face-to-face interview was carried out to syndrome. Random clustered sampling permanent inhabitants aged 18-80 years under stratification urban suburban areas. life evaluated using Chinese version SF-36.A total 4178 subjects (1907 male 2271 female) were interviewed. adjusted is 11.50% according Manning criteria 5.67% Rome II...
An analysis of pp\ifmmode\bar\else\textasciimacron\fi{} collision events at \ensuremath{\surd}s =1.8 TeV with jets and large missing transverse energy finds no event >40 GeV. This result yields a 90%-C.L. limit on the cross section for one-jet-event production <0.1 nb jet in pseudorapidity range \ensuremath{\Vert}\ensuremath{\eta}\ensuremath{\Vert}<1.0 ${E}_{T}$>52 Limits masses squarks gluinos minimal supersymmetry model are also set. At 90% C.L., ${m}_{q\ifmmode \tilde{}\else...
Posttraumatic stress disorder (PTSD) affects 5–10% percent of the US adult population with a higher prevalence among women compared men. Although it remains unclear how biological sex associates susceptibility to PTSD, one mechanism may involve role for estrogen in gene by environment interaction. We previously demonstrated sex-dependent association between pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) and where carriers C allele at single-nucleotide polymorphism...
The bed nucleus of the stria terminalis (BNST) is a forebrain region highly responsive to stress that expresses corticotropin-releasing hormone (CRH) and implicated in mood disorders, such as anxiety. However, exact mechanism by which chronic induces CRH-mediated dysfunction BNST maladaptive behaviors remains unclear. Here, we first confirmed selective acute optogenetic activation oval (ovBNST) increases avoidance male mice. Next, found 6 week variable mild (CVMS) paradigm resulted increased...
Coronary atherosclerotic heart disease is an important, worldwide burden on human health. Central muscle infarction the most dangerous condition, has highest mortality and disability rates, gradually becoming more common among young people. After myocardial infarction, neutrophils recruited to infarcted area promote inflammatory response by releasing proinflammatory factors chemokines release matrix metalloproteinases myeloperoxidases that degrade extracellular produce reactive oxygen...
A search for tt\ifmmode\bar\else\textasciimacron\fi{}\ensuremath{\rightarrow}e\ensuremath{\mu}+X in pp\ifmmode\bar\else\textasciimacron\fi{} collisions at s\ensuremath{\surd}\ifmmode\bar\else\textasciimacron\fi{} TeV is described. The production and decay of top-quark--antiquark pairs considered the context standard model. analysis based on data with an integrated luminosity 4.4 ${\mathrm{pb}}^{\mathrm{\ensuremath{-}}1}$ recorded Collider Detector Fermilab. An upper limit...
An analysis of ${Z}^{0}$\ensuremath{\rightarrow}${e}^{+}$${e}^{\mathrm{\ensuremath{-}}}$ and ${Z}^{0}$\ensuremath{\rightarrow}${\ensuremath{\mu}}^{+}$${\ensuremath{\mu}}^{\mathrm{\ensuremath{-}}}$ data from the Collider Detector at Fermilab in p\ifmmode\bar\else\textasciimacron\fi{}p collisions \ensuremath{\surd}s =1.8 TeV yields a mass ${Z}^{0}$ boson ${M}_{Z}$=90.9\ifmmode\pm\else\textpm\fi{}0.3 (stat+syst)\ifmmode\pm\else\textpm\fi{}0.2 (scale) GeV/${c}^{2}$ width...
Background and study aim: The aim of this was to determine the prevalence, characteristics, risk factors erosive esophagitis Barrett's esophagus in an adult Chinese population without gastroesophageal reflux symptoms.
Background Chronic stress or prolonged administration of glucocorticoids suppresses proliferation and/or survival newborn cells in adult rat dentate gyrus. Earlier we showed that the glucocorticoid receptor antagonist mifepristone during final 4 days a 21 period corticosterone treatment fully normalized number cells. Here aimed to better understand how achieves this effect and questioned whether an even shorter (single day) (instead days) also suffices normalize neurogenesis. Methods We...
Abstract Early-life stress (ELS) leads to stress-related psychopathology in adulthood. Although dysfunction of corticotropin-releasing hormone (CRH) signaling the bed nucleus stria terminalis (BNST) mediates chronic stress-induced maladaptive affective behaviors that are historically associated with mood disorders such as anxiety and depression, it remains unknown whether ELS affects CRH function adult BNST. Here we applied a well-established paradigm (24 h maternal separation (MS) at...
An analysis of high-transverse-momentum electrons using data from the Collider Detector at Fermilab (CDF) ¯pp collisions √s=1800 GeV yields values production cross section times branching ratio for W and Z0 bosons σ(¯pp→WX→eνX)=2.19±0.04(stat)±0.21(syst) nb σ(¯pp→Z0X→e+e−X)=0.209±0.013(stat)±0.017(syst) nb. Detailed descriptions CDF electron identification, background, efficiency, acceptance are included. Theoretical predictions sections that include a mass top quark larger than mass,...
Inclusive jet production at √s=1.8 TeV has been measured in the CDF detector Fermilab Tevatron ¯pp Collider. Jets with transverse energies (Et) up to 250 GeV have observed. The Et dependence of inclusive cross section is consistent leading-order quantum-chromodynamic calculations, and comparison lower-energy data shows deviations from scaling QCD. A lower limit 700 (95% confidence level) placed on quark compositeness scale parameter Λc associated an effective contact interaction.Received 3...
Seroprevalence data from 1501 subjects was used to test the hypothesis that Helicobacter pylori may be transmitted by fecaloral route. Antibody hepatitis A virus as a marker of fecal-oral exposure. Of subjects, 35.5% were seropositive for both H. and A, 19.1%were seronegative both, 36.5% only, 8.8% only. Cross-sectional rural areas supported an association between pylori. However, in urban area there no evidence infection persons <10 years old, yet seroprevalence high this group (∼ 32%)....