A5046710765- Dental Radiography and Imaging
- Bone and Dental Protein Studies
- dental development and anomalies
- Oral and Maxillofacial Pathology
- Periodontal Regeneration and Treatments
- Temporomandibular Joint Disorders
- MicroRNA in disease regulation
- Endodontics and Root Canal Treatments
- Facial Trauma and Fracture Management
- Oral microbiology and periodontitis research
- Orthodontics and Dentofacial Orthopedics
- Dental Implant Techniques and Outcomes
- Cell death mechanisms and regulation
- Cancer-related gene regulation
- Curcumin's Biomedical Applications
- Bone Tissue Engineering Materials
- NF-κB Signaling Pathways
- RNA Research and Splicing
- Amino Acid Enzymes and Metabolism
- Facial Nerve Paralysis Treatment and Research
- Epigenetics and DNA Methylation
- RNA Interference and Gene Delivery
- Cholesterol and Lipid Metabolism
- Oropharyngeal Anatomy and Pathologies
- Osteoarthritis Treatment and Mechanisms
Chosun University
2015-2025
University of Dental Medicine
2003
The mammalian tooth forms by a series of reciprocal epithelial-mesenchymal interactions.Although several signaling pathways and transcription factors have been implicated in regulating molar crown development, relatively little is known about the regulation root development.Four genes encoding nuclear factor I (NFI) transcription-replication proteins are present mouse genome: Nfia, Nfib, Nfic, Nfix.In order to elucidate its physiological role(s), we disrupted Nfic gene mice.Heterozygous...
Background: Nuclear factor I genes play an important role in the development of brain, lung, and roots teeth. We had reported that Nfic ‐deficient mice form normal crowns, but abnormal molar However, mechanism by which disruption gene causes root formation remains unknown. Methods: To understand this mechanism, was examined compared to wild‐type morphological, immunohistochemical, situ hybridization analyses. Results: formed Hertwig's epithelial sheath (HERS) severely disrupted odontoblast...
In bone marrow, marrow stromal cells (BMSCs) have the capacity to differentiate into osteoblasts and adipocytes. Age-related osteoporosis is associated with a reciprocal decrease of osteogenesis an increase adipogenesis in marrow. this study, we demonstrate that disruption nuclear factor I-C (NFI-C) impairs osteoblast differentiation formation, increases Interestingly, NFI-C controls postnatal formation but does not influence prenatal development. We also found decreased expression...
This study investigated the expression and localization of APin (which was previously identified cloned from a rat odontoblast cDNA library), during ameloblast differentiation in incisors, by using situ hybridization immunohistochemistry. The subcellular varied differentiation, but stage‐specific. mRNA not expressed pre‐ameloblasts, weakly secretory ameloblasts, strongly maturation‐stage ameloblasts as well junctional epithelium attached to enamel erupted molars. In protein conspicuous...
Transforming growth factor-β1 (TGF-β1) signaling plays a key role in vertebrate development, homeostasis, and disease. Nuclear factor I-C (NFI-C) has been implicated TGF-β1 signaling, extracellular matrix gene transcription, tooth root development. However, the functional relationship between NFI-C remains uncharacterized. The purpose of this study was to identify molecular interactions mouse odontoblasts. Real-time polymerase chain reaction western analysis demonstrated that expression...
This study aimed to measure the thickness of epithelium and lamina propria palatal mucosa elucidate location greater palatine artery provide anatomical basis for subepithelial connective tissue grafting. Thirty-two maxillary specimens, taken from canine distal area first molar area, were embedded in paraffin stained with hematoxylin-eosin. The was measured at three positions on these starting 3 mm below alveolar crest 3-mm intervals. evaluated by using image-processing software. mean...
Jeong-Yeon Seo, Tae-Hyeon Kim, Kyeong-Rok Kang, HyangI Lim, Moon-Chang Choi, Do Kyung Hong Sung Chun, Heung-Joong Sun-Kyoung Yu, and Jae-Sung Kim. Mol. Cells -0001;0:. https://doi.org/10.14348/molcells.2023.2149
The purpose of this study was to examine the effect 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH), an inhibitor L-type amino transporters, on cell growth suppression in KB human oral cancer cells and roles cycle regulatory factors BCH-induced inhibition. BCH influence inhibition were examined using analysis, immunoblotting immunoprecipitation. treatment induced arrest at G1 phase cells. expression cyclin D3 remarkably decreased by treatment. inhibited cyclin-dependent protein kinase...
25-hydroxycholesterol (25-HC) is an oxysterol synthesized from cholesterol by cholesterol-25-hydroxylase during metabolism. The aim of this study was to verify whether 25-HC induces oxiapoptophagy in fibroblasts. not only decreased the survival L929 cells, but also increased number cells with condensed chromatin and altered morphology. Fluorescence-activated cell sorting results showed that there a dose-dependent increase apoptotic populations upon treatment 25-HC. 25-HC-induced death...
The purpose of this study was to identify the potential projection errors posteroanterior cephalometric radiographs due head rotation in vertical Z-axis. For investigation, 20 human dry skull samples with permanent dentition were collected from Department Anatomy College Medicine, Chosun University, Korea. They had no gross asymmetries and well preserved. Each rotated 0 degrees +/- 10 at 1 intervals. A axis, Z-axis, used as a rotational axis for exposure 420 radiographs. Most abscissa values...