A5045898693- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- COVID-19 and healthcare impacts
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Dysphagia Assessment and Management
- Hernia repair and management
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic and Hepatic Oncology Research
- Respiratory and Cough-Related Research
- Stoma care and complications
- Thyroid and Parathyroid Surgery
- Colorectal and Anal Carcinomas
- Head and Neck Anomalies
- Cancer Genomics and Diagnostics
- Airway Management and Intubation Techniques
- Gastrointestinal disorders and treatments
- Trauma and Emergency Care Studies
- Renal cell carcinoma treatment
- Metastasis and carcinoma case studies
- Appendicitis Diagnosis and Management
- Surgical site infection prevention
Paracelsus Medical University
2017-2025
Salzburger Landeskliniken
2021-2024
Unfallkrankenhaus Salzburg
2022
Paracelsus Medizinische Privatuniversität
2018
Ordensklinikum Linz Barmherzige Schwestern
2015
The aim of this study was to compare the diagnostic accuracy salivary pepsin with oropharyngeal pH monitoring using Restech measurement system (Dx-pH) for diagnosis laryngopharyngeal reflux (LPR).Prospective cohort study.Seventy patients primary symptoms related LPR underwent gastroscopy, high-resolution manometry, throughout 24-hour (MII-pH), and barium esophagography between October 2015 May 2018. In addition, an ear, nose, throat examination performed, including assessment Belafsky Reflux...
To support the global restart of elective surgery, data from an international prospective cohort study 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical with SARS-CoV-2. We found that patient rather than operation factors were best predictors and used these create COVIDsurg Mortality Score (https://covidsurgrisk.app). Our demonstrates it is safe wide range services selected patients.
The assessment of hiatal hernias (HH) is typically done with barium swallow X‑ray, upper endoscopy, and by high-resolution esophageal manometry (HRM). aim this study was to assess the clinical utility these methods in terms HH detection their correlation gastroesophageal reflux disease (GERD). A retrospective comparative analysis patients symptoms GERD carried out. performance endoscopy HRM diagnosing assessed, taking X‑ray as a reference. Furthermore, statistically between detected presence...
Abstract Background Previous studies suggest clinical effectiveness of endoscopic full-thickness plication in selected patients with gastroesophageal reflux disease (GERD). The aim this study was to assess the safety and efficiency GERDx™ device by evaluating parameters, symptom scores, quality life (QoL). Methods Prospective one-arm trial outcome forty GERD subjected device. We included at least one typical despite treatment a PPI for > 6 months, pathologic esophageal acid exposure,...
Abstract Reasons for structural and outcome differences in esophageal cancer surgery Western Europe remain unclear. This questionnaire study aimed to identify the organization of surgical care Europe. A cross-sectional international was conducted among upper gastrointestinal (GI) surgeons from One surgeon per country selected based on scientific output active membership European Society Diseases Esophagus or (inter)national GI committee. The consisted 51 structured questions surgery,...
The aim of the present trial is to investigate clinical efficiency GERDx device for patients with gastroesophageal reflux disease (GERD).Prospective study evaluating Gastrointestinal Quality Life Index, symptoms scores, as well esophageal manometry and impedance-pH-monitoring data at baseline 3 months after endoscopic full-thickness plication device.In total, 28 underwent procedure so far. Mean Index DeMeester general reflux-specific scores improved (P<0.01). Three 6 patients, who were...
This study investigates if pledgeted sutures for hiatal closure could be an alternative to mesh the surgical treatment of large hernia. Forty-one patients who underwent laparoscopic 270° Toupet fundoplication with sutured crura between September 2014 and April 2017 were evaluated regard recurrence hernia at 3 months 1 year after surgery. Indication pledgets was a surface area least 5.60 cm2, or migration more than 1/3 stomach into thorax preoperative size > 5 cm. The integrity repair...
Impaired E-cadherin (Cdh1) functions are closely associated with cellular dedifferentiation, infiltrative tumor growth and metastasis, particularly in gastric cancer. The class-I carcinogen Helicobacter pylori (H. pylori) colonizes epithelial cells induces Cdh1 shedding, which is primarily mediated by the secreted bacterial protease high temperature requirement A (HtrA). In this study, we used human primary cell lines derived from gastroids mucosoids different healthy donors to investigate...
Sophisticated immune evasion strategies enable
Some medical disciplines have reported a strong decrease of emergencies during the coronavirus disease 2019 (COVID-19) pandemic; however, effect lockdown on general surgery remains unclear.This study is retrospective, multicenter analysis emergency operations performed period from 1 March to 15th 2020 and in same time three centers providing surgical care area Salzburg-North, Austria.In total 165 surgeries were compared 287 2019. This significant 122 (42.5%) COVID-19 (p = 0.005). The length...
The aim of this study was to evaluate the value salivary pepsin and oropharyngeal pH-monitoring assess surgical outcome patients with laryngopharyngeal reflux (LPR).Twenty consecutive LPR despite proton pump inhibitor treatment received laparoscopic antireflux surgery. Twenty-four hour esophageal (multichannel intraluminal impedance monitoring [MII]-pH) manometry (high-resolution manometry) data were documented preoperatively at 3-month follow-up. An ears, nose throat (ENT) examination...
Patients with incisional hernias (IH) and risk factors for surgical site occurrences (SSOs) such as defined comorbidities and/or potential contaminations are considered to be treated bioprosthetics. A retrospective analysis of consecutive patients who had undergone elective IH repair synthetic mesh materials between 2009 2013 was conducted. Only were classified into Grades II III according the classification Ventral Hernia Working Group (VHWG) study. Primary outcome parameter incidence SSO....
Sexual function is crucial for the quality of life and can be highly affected by preoperative therapy surgery. The aim this study was to identify potential risk factors poor sexual life.Female patients were asked complete Female Function Index (FSFI-6). Male demanded answer International Erectile (IIEF-5).In total, 79 filled in questionary, yielding a response rate 41.57%. proportion women represented 32.91%, median age 76.0 years (66.0-81.0). dysfunction appeared 88.46% female patients....
Intraductal papillary mucinous neoplasms (IPMNs) represent the most common precancerous cystic lesions of pancreas. The aim our study was to investigate if resection for non-invasive IPMNs alters quality life (QoL) in a long-term follow-up.Patients (n = 50) included analysis were diagnosed and resected from 2010 2016. QoL assessed at median 5.5 years after resection. At that point time, current as well before evaluated retrospectively. standardised European Organisation Research Treatment...
This study assessed the impact of a prophylactic, 3D funnel-shaped intraperitoneal mesh on rate parastomal hernia after abdominoperineal rectum resection with permanent end colostomy.Data from 76 patients receiving colostomy between 2013 and 2018 were collected retrospectively. Occurrences reoperation due to in without prophylactic compared by univariate, multivariate, propensity score-adjusted analyses.Twenty-two (28.9%) included received mesh. The mean follow-up was 39.3 ± 23.8 months....