A5102909862- Spinal Cord Injury Research
- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Mesenchymal stem cell research
- Pregnancy-related medical research
- Circular RNAs in diseases
- Diet and metabolism studies
- Gynecological conditions and treatments
- Natural Compounds in Disease Treatment
- Cancer-related Molecular Pathways
- MicroRNA in disease regulation
- Spinal Dysraphism and Malformations
- Nerve injury and regeneration
- Cancer-related molecular mechanisms research
Second Affiliated Hospital of Xi'an Jiaotong University
2021-2023
Tangshan People's Hospital
2015-2016
Aberrantly expressed microRNAs (miRNAs) after spinal cord injury (SCI) participate in diverse biological pathways and processes, including apoptosis, inflammation, oxidative stress responses, peroxidation, ferroptosis. This study was aimed at exploring the mechanisms underlying miRNA-mediated ferroptosis an SCI rat model. In present study, a T10 weight-dropping model established miRNA profiling used to detect expression profiles post-SCI. Basso-Beattie-Bresnahan scores inclined plane test,...
Lithium is associated with oxidative stress and apoptosis, but the mechanism by which lithium protects against spinal cord injury remains poorly understood. In this study, we found that intraperitoneal administration of chloride (LiCl) in a rat model alleviated pathological inhibited expression tumor necrosis factor α, interleukin-6, interleukin 1 β. pyroptosis reduced inflammation inhibiting Caspase-1 expression, reducing response, activation Nod-like receptor protein 3 inflammasome. We...