A5103244077- Medical Imaging and Analysis
- Chalcogenide Semiconductor Thin Films
- Spine and Intervertebral Disc Pathology
- Quantum Dots Synthesis And Properties
- Perovskite Materials and Applications
- Spinal Cord Injury Research
- Musculoskeletal pain and rehabilitation
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- Medical Research and Treatments
- Ubiquitin and proteasome pathways
- Spinal Fractures and Fixation Techniques
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related gene regulation
- Tryptophan and brain disorders
- Genetic Syndromes and Imprinting
- Galectins and Cancer Biology
- Nosocomial Infections in ICU
- Supercapacitor Materials and Fabrication
- Genomics, phytochemicals, and oxidative stress
- Cervical and Thoracic Myelopathy
- Precipitation Measurement and Analysis
- Soil and Water Nutrient Dynamics
- Protein Tyrosine Phosphatases
Fujian Medical University
2023-2025
Union Hospital
2025
Pingjin Hospital
2025
East China Normal University
2010-2024
University of Electronic Science and Technology of China
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2010-2022
Xi'an Chest Hospital
2021
Xi'an Jiaotong University
2021
Shanghai Meteorological Bureau
2020
Luohe Medical College
2020
The ever-growing demand for wearable electronic devices is stimulating the development of novel materials fabrication flexible electronics. Among all promising candidates, polysaccharide-based hydrogels are constructing a prospective pattern achieving functionalities, benefiting from their ecofriendliness, renewability, biodegradability, and sustainability. However, one most important drawbacks these slow self-healing. To address abovementioned issue, we propose simple method to fabricate...
TRAF [TNF (tumour necrosis factor)-receptor-associated factor] 2 and 6 are essential adaptor proteins for the NF-κB (nuclear factor κB) signalling pathway, which play important roles in inflammation immune response. Polyubiquitination of TRAF2 TRAF6 is critical to their activities functions TNFα- IL (interleukin)-1β-induced activation. However, regulation by deubiquitination remains incompletely understood. In present study, we identified USP (ubiquitin-specific protease) 4 as a novel...
The proproliferative transcription factor KLF5 plays an important role in promoting cell proliferation and tumorigenesis. is a short-lived protein that can be rapidly degraded through the ubiquitin-proteasome pathway cancer cells. However, mechanisms regulating stability remain poorly understood. In this study, tumor suppressor Fbw7, component of SCF complex (SCF(Fbw7)) E3 ubiquitin ligase, specifically promoted degradation ubiquitination but had little effect on KLF4. Fbw7 interacted with...
Aberrantly expressed microRNAs (miRNAs) after spinal cord injury (SCI) participate in diverse biological pathways and processes, including apoptosis, inflammation, oxidative stress responses, peroxidation, ferroptosis. This study was aimed at exploring the mechanisms underlying miRNA-mediated ferroptosis an SCI rat model. In present study, a T10 weight-dropping model established miRNA profiling used to detect expression profiles post-SCI. Basso-Beattie-Bresnahan scores inclined plane test,...
Abstract Quasi‐one‐dimensional antimony sulfoselenide (Sb 2 (S,Se) 3 ) semiconductor is one of the most promising light‐harvesting materials owing to its simple phase and tunable absorption spectra. However, oriented [Sb 4 6 ] n ribbons Sb thin films nearly horizontally stacked in parallel substrate severely hinders transport carriers, yet critical control absorber orientation growth for high‐performance solar cells. Herein, a new close spaced sublimated (CSS) CdS buffer layer with high...
Antimony chalcogenide (Sb2(S,Se)3) semiconductors have been demonstrated as a promising absorber material for highly efficient inorganic solar cells. Especially, tunable band gaps make them fascinating in the photovoltaic field, thanks to reciprocal replacement of Se and S atoms. Herein, series Sb2(S,Se)3 films with continuously were reported through typical vapor transport deposition process. We concluded relationship Se/S ratio between evaporation source deposited film successfully...
Arginine methylation broadly occurs in histones and has been linked to transcriptional regulation, cell cycle regulation DNA repair. While numerous proteins (histone code effectors) that specifically recognize or read the methylated lysine residues core have identified, little is known for effectors specific arginines histones. In this study, we attempted identify effector(s) recognizing asymmetrically R17 R26 H3, which are catalyzed by CARM1/PRMT4, through an unbiased biochemical approach....
Abstract We have investigated the cytotoxic and antitumour activity of an octadecenoic acid extract, mainly containing oleic linoleic acids, from Euphorbia kansui on human gastric (SGC-7901), hepatocellular carcinoma (BEL-7402), leukaemia (HL-60) tumour cell strains. Significant dose-dependent antiproliferation effects were observed cells dose 3.2 μg mL−1, which comparable with or better than those common agent 5-fluorouracil. Results clone formation assay flow cytometry indicated that...
SCP1 as a nuclear transcriptional regulator acts globally to silence neuronal genes and affect the dephosphorylation of RNA Pol ll. However, we report first finding description plasma membrane-localized protein in various cancer cells using EGFP- or other epitope-fused SCP1. Membrane-located dephosphorylates AKT at serine 473, leading abolishment 473 phosphorylation that results suppressed angiogenesis decreased risk tumorigenesis. Consistently, observed increased followed by enhanced...
Confocal Raman microspectral imaging was adopted to elucidate the cellular drug responses of osteosarcoma cells (OC) N-[N-(3, 5-difluorophenyl acetyl)-L-alanyl]-sphenylglycine butyl ester (DAPT), a γ-secretase inhibitor, by identifying induced subcellular compositional and structural changes.Methods: Spectral information were acquired from cultured treated with 0 (Untreated Group, UT), 10 (10 μM DAPT treated, 10T), 20 (20 20T) for 24 hours.A one-way ANOVA Tukey's honest significant...
Previous studies by our group have demonstrated that the transplantation of exogenous platelet-derived growth factor (PDGF)-AA-overexpressing oligodendrocyte progenitor cells (OPCs) promotes tissue repair and recovery neurological function in a rat model spinal cord injury (SCI). However, it remains unclear whether treatment with PDGF-AA also affects endogenous oligodendrocytes (OL) or even neurons, thus promoting further functional after SCI. In present study, we evaluated therapeutic...
To evaluate the long-term curative efficacy and safety of olfactory ensheathing cell (OEC) transplantation by 10 years follow-up investigation. A observation was done on 13 patients with allograft bulb-derived OEC from September 2005 to 2007 at Second Affiliated Hospital Xi'an Jiaotong University. After purification, amplification, identification, a 2 × 107/mL suspension prepared for transplantation. In posterior horn spinal cord 0.5 cm distal proximal injury zone, 4 needle points were...
MicroRNA (miR)‑31 serves a key role in various biological processes, including tumor development, angiogenesis and inflammation. Whether miR‑31 is involved the pathological processes of arteriosclerosis obliterans (ASO) remains to be elucidated, as does mechanism regulation arterial smooth muscle cells (ASMCs). In present study, expression was detected by reverse transcription‑quantitative polymerase chain reaction situ hybridization, significantly upregulated human ASO walls compared with...
All-Vacuum-Process In article number 2214511, Jiahua Tao, Shaoqiang Chen, Xiaobo Hu, and co-workers develop a newly close spaced sublimated CdS buffer layer used for high-performing Sb2(S,Se)3 solar cells with an efficiency of 7.12%. This study opens up novel CSS-CdS layers cells, which is great importance all-vacuum processing so that thin-film can be manufactured by in-line.