A5000034926- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Law and Political Science
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Digitalization, Law, and Regulation
- Medical and Health Sciences Research
- Nerve Injury and Rehabilitation
- Trauma Management and Diagnosis
- Tendon Structure and Treatment
- Diverse Legal and Medical Studies
- Corporate Governance and Law
- Orthopaedic implants and arthroplasty
- Criminal Law and Policy
- Sports injuries and prevention
- Labor Movements and Unions
- Bone health and treatments
- Medical Practices and Rehabilitation
- Public Administration and Political Analysis
- Social Policies and Healthcare Reform
- Social and Demographic Issues in Germany
- Health and Medical Studies
- Clostridium difficile and Clostridium perfringens research
- Economic and Social Issues
- Helicobacter pylori-related gastroenterology studies
Regensburg University of Applied Sciences
2015-2024
University Hospital Regensburg
2020-2024
Hôpital de la Croix-Rousse
2024
Hospices Civils de Lyon
2024
Arthrex (Germany)
2020
University of Bonn
2019
University of Regensburg
2019
Charité - Universitätsmedizin Berlin
2006-2015
WinnMed
2015
Assaf Harofeh Medical Center
2014
The incidence of rotator cuff tears and recurrent defects positively correlate with patient age. However, this observation has never been analysed at the cellular level. present study aims to better understand correlation by investigating characteristics tenocytes different age groups. Additionally, previous studies reported on stimulating effects Bone Morphogenetic Protein (BMP) -2 BMP-7 tenocytes. Thus, second aim was investigate, whether stimulation potential demonstrates age-related...
ABSTRACT Homologs of the ferric uptake regulator Fur and iron storage protein ferritin play a central role in maintaining homeostasis bacteria. The gastric pathogen Helicobacter pylori contains an iron-induced prokaryotic (Pfr) which has been shown to be involved protection against metal toxicity homolog not functionally characterized H. . Analysis isogenic fur -negative mutant revealed that is required for metal-dependent regulation ferritin. Iron starvation, as well medium supplementation...
ABSTRACT The reactivity of the essential element iron necessitates a concerted expression ferritins, which mediate storage in nonreactive state. Here we have further established role Helicobacter pylori ferritin Pfr metabolism and gastric colonization. Iron stored enabled H. to multiply under severe starvation protected bacteria from acid-amplified toxicity, as inactivation pfr gene restricted growth these conditions. lowered total content mutant, is probably caused by decreased uptake...
Humeral rotation often remains compromised after nonlateralized reverse shoulder arthroplasty (RSA). Reduced rotational moment arms and muscle slackening have been identified as possible reasons for this impairment. Although several clinical studies suggest lateralized RSA may increase rotation, it is unclear whether attributable to preservation of pretension the remaining rotator cuff.The was analyzed determine (1) (2) origin-to-insertion distances teres minor subscapularis can be...
Rotator cuff tears are common soft tissue injuries of the musculoskeletal system that heal by formation repair and may lead to high retear rates joint dysfunction. In particular, from chronic, large tendon is such degenerative nature it be prone after surgical repair. Besides several biomechanical approaches, biologically based strategies as application growth factors promising for increasing cell activity production extracellular matrix at tendon-to-bone unit. As a precondition subsequent...
Background: Treatment of first-time shoulder dislocation (FSD) is a topic debate. After high rates recurrent instability after nonoperative management were reported in the literature, primary repair FSD significantly increased. At same time, new concepts proposed that had promising results for immobilization external rotation (ER) and abduction (ABD). Purpose: The aim this study was to evaluate recurrence (primary outcome) clinical outcomes (secondary outcome parameters) ER+ABD versus...
After reverse shoulder arthroplasty (RSA) external and internal rotation will often remain restricted. A postoperative alteration of the biomechanics in remaining cuff is discussed as a contributing factor to these functional deficits. In this study, muscle moment arms well origin-to-insertion distance (OID) were calculated using three-dimensional models derived from CT scans seven cadaveric specimens. Moment for humeral are significantly smaller cranial segments SSC all TMIN abduction...
Superior capsular reconstruction (SCR) represents a new option for the treatment of irreparable rotator cuff tears.This study aimed to evaluate clinical and radiologic outcomes SCR compare them with partial repair (PR) infraspinatus tendon. The hypothesis was that there would be no significant differences between outcome parameters PR after minimum follow-up 2 years.Cohort study; Level evidence, 3.Of 21 patients who underwent SCR, 20 were matched in 1:1 ratio according sex, age, tear...
Zoledronic acid (ZOL) has been shown in vitro and vivo to inhibit osteoclastic activity regulate osteoblasts. Its antiresorptive effect is used clinically the treatment of bone-consuming pathologies prevent skeletal complications. Because its on bone cells, there might be a possible benefit fractures by local application from biodegradable poly(D,L-lactide) (PDLLA) coating osteosynthetic implants. We analyzed locally applied ZOL PDLLA intramedullary implants fracture healing.Standardized...
An implant coating with poly(D, L-lactide) (PDLLA) releasing incorporated zoledronic acid (ZOL) has already proven to positively effect osteoblasts, inhibit osteoclasts and accelerate fracture healing. Aim of this study was investigate the release kinetics chosen different concentrations ZOL locally released from on osseointegration implants.For C14-labled out monitored over a period six weeks in vitro. For testing osseointegration, titanium Kirschner wires were implanted into medullary...
Background: Many clinical and radiographic studies suggest that patient age sex have an influence on rotator cuff (RC) repair outcomes. However, these findings result from retrospective statistical analyses cannot provide a causal answer. Purpose: To analyze whether the biological potential at time of RC or midterm Also assessed was effect intraindividual clinical/radiographic results. Study Design: Cohort study; Level evidence, 2. Methods: A total 40 patients underwent arthroscopic repair....