Fabiana Manica

ORCID: 0000-0003-1673-2815
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About
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Research Areas
  • Alkaloids: synthesis and pharmacology
  • Berberine and alkaloids research
  • Folate and B Vitamins Research
  • Urological Disorders and Treatments
  • Bioactive Compounds and Antitumor Agents
  • Metabolism and Genetic Disorders
  • Natural product bioactivities and synthesis
  • Congenital Anomalies and Fetal Surgery
  • Virus-based gene therapy research
  • RNA Interference and Gene Delivery
  • Retinoids in leukemia and cellular processes
  • Prenatal Substance Exposure Effects
  • Traditional and Medicinal Uses of Annonaceae
  • Monoclonal and Polyclonal Antibodies Research

Universidade Federal de Ciências da Saúde de Porto Alegre
2017-2022

Université Laval
2020

Universidade Federal do Rio Grande do Sul
2016-2017

We have generated polyclonal and monoclonal antibodies by genetic immunization over the last two decades. In this paper, we present our most successful methodology acquired these years animals in which obtained highest rates of success. The technique presented is convenient, easy, affordable, generates against mammalian proteins their native form. This protocol requires neither expensive equipment, such as a gene gun, nor sophisticated techniques conjugation gold microspheres,...

10.3390/ijms21197074 article EN International Journal of Molecular Sciences 2020-09-25

Omphalocele is an abnormality of the closure abdominal wall, whose defect covered by a membrane and located in umbilical cord. Our aim was to report case concomitant occurrence omphalocele ectrodactyly, association considered quite rare. The patient pregnant woman her first pregnancy. She referred for evaluation due fetal finding associated with cord cyst on second trimester ultrasound. Magnetic resonance imaging performed later agreement findings ultrasound study, showing wall containing...

10.1002/uog.25597 article EN Ultrasound in Obstetrics and Gynecology 2022-09-01
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