A5048686006- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Orthopaedic implants and arthroplasty
- Elbow and Forearm Trauma Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Hip and Femur Fractures
- Orthopedic Infections and Treatments
- Emergency and Acute Care Studies
- Knee injuries and reconstruction techniques
- Bone fractures and treatments
- Shoulder Injury and Treatment
- Anesthesia and Pain Management
- Peripheral Nerve Disorders
- Interprofessional Education and Collaboration
- Musculoskeletal pain and rehabilitation
- Growth Hormone and Insulin-like Growth Factors
- Medical Malpractice and Liability Issues
- Musculoskeletal synovial abnormalities and treatments
- Osteoarthritis Treatment and Mechanisms
- Trauma and Emergency Care Studies
- Venous Thromboembolism Diagnosis and Management
- Injury Epidemiology and Prevention
- Innovations in Medical Education
- Spine and Intervertebral Disc Pathology
- Intensive Care Unit Cognitive Disorders
Aarhus University
2015-2024
Regional Hospital Holstebro
2015-2024
Regional Hospital West Jutland
2013-2024
Glostrup Hospital
2022-2024
Regionshospitalet Herning
1994-2024
Collaborative Group (United States)
2023
Aarhus University Hospital
1994-2023
Aalborg University
2023
Lundbeck (Denmark)
2012-2018
Rigshospitalet
2015-2018
Background: Accelerated perioperative rehabilitation protocols following total hip and knee arthroplasties are currently being implemented worldwide, but the cost-effectiveness of these from a societal perspective is not known. We compared an accelerated care protocol with that more standard for patients treated arthroplasty. Methods: A study was undertaken as piggybacked on randomized clinical trial comparing early outcomes intensive postoperative regimen those protocol. assessed...
Postoperative cognitive dysfunction (POCD) is reported to occur after major surgery in as many 20% of patients, elderly patients may especially experience problems the weeks and months surgery. Recent studies vary greatly methods evaluation diagnosis POCD, pathogenic mechanisms are still unclear. We evaluated a large uniform cohort standardized approach, joint replacement (total hip knee replacement). Patients were an optimized perioperative approach (fast track) with multimodal...
International guidelines recommend thrombosis prophylaxis after total hip arthroplasty (THA) and knee (TKA) for up to 35 days. However, previous studies often have hospital stays (length of stay; LOS) 8-12 days not considering early mobilisation, which may reduce incidence venous thromboembolic events (VTE). We investigated the any symptomatic (TEEs) with only in-hospital if LOS ≤5 fast-track THA TKA.A prospective descriptive multicentre cohort study in TKA from February 2010 December 2011,...
Background Pre‐operative opioid use has been suggested to increase post‐operative pain and consumption after total knee arthroplasty ( TKA ), but previous studies are either retrospective or inhomogeneous with regard surgical procedures control of analgesic regimes, few opioid‐treated patients, hindering firm conclusions. Methods In a prospective observational study, we investigated the effect > 4 weeks pre‐operative [none vs. low dose (< 30 mg morphine equivalents (eq.)) high (>...
Purpose — To compare the risks of re-admission, reoperation, and mortality within 90 days surgery in orthopedic departments with well-documented fast-track arthroplasty programs those all other Denmark from 2005 to 2011. Methods We used Danish hip knee registers identify patients primary total or arthroplasty. Information about was obtained administrative databases. The cohort consisted 6 departments. national comparison Regression methods were calculate relative risk (RR) adverse events,...
In Denmark, patients with rheumatoid arthritis (RA) are registered in the nationwide clinical DANBIO quality register and Danish National Patient Registry (DNPR). The aim was to study validity of RA diagnosis estimate completeness relevant cases each registry.Patients for first time 2011 a were identified DNPR January 2013. For DNPR, filters applied reduce false-positive cases. verified by review patient records. We calculated positive predictive values (PPVs) registrations estimated...
Abstract “Fast-track” protocols has improved surgical care with a reduction in length of hospital stay (LOS) total hip (THA) and knee arthroplasty (TKA). However, the effects continuous refinement perioperative lack detailed assessment. We studied time-related changes LOS morbidity after THA TKA within collaboration scientific care. Prospective multicentre consecutive cohort study between 2010 2017 from nine high-volume orthopaedic centres established fast-track protocols. collection...
Pain catastrophizing contributes to acute and long-term pain after knee arthroplasty (KA), but the association between physical function is not clear. We examined preoperative one year surgery, as well differences in function, general health two groups of patients with high low score.We included 615 scheduled for KA March 2011 December 2013. Patients completed The Catastrophizing Scale (PCS) prior surgery. Oxford Knee Score (OKS), Short Form-36 (SF-36) EuroQol-5D (EQ-5D) were 4 12 months...
‘Fast-track’ surgery was introduced more than 20 years ago and may be defined as a co-ordinated peri-operative approach aimed at reducing surgical stress facilitating post-operative recovery. The fast-track programmes have now been into total hip arthroplasty (THA) with reduction in length of stay, shorter convalescence rapid functional recovery without increased morbidity mortality. This has achieved by focusing on multidisciplinary collaboration establishing ‘fast-track’ units,...
Background and purpose - Pain catastrophizing contributes to acute long-term pain after total knee arthroplasty (TKA) but currently there are only limited treatment options. This study investigates the effectiveness of patient education in coping among patients with moderate high score before TKA. Secondary outcomes were physical function, quality life, self-efficacy, catastrophizing.Patients methods The was a parallel-group randomized controlled trial including levels catastrophizing. 60...
The effects of GH substitution on skeletal mass, bone turnover, and calcium metabolism were investigated in 29 patients with deficiency who randomized to sc injections (2 IU/m2 day) or placebo for 12 months. During treatment, serum insulin-like growth factor I increased 263 +/- 98% (P < 0.001). Serum osteocalcin, a alkaline phosphatase, procollagen type C-terminal propeptide by 376 78% 0.005), 128 17% 100 respectively. collagen telopeptide urinary levels pyridinoline, deoxypyridinoline,...
In Denmark, approximately 12,000 hip and knee arthroplasties were performed in 2006, the hospital costs close to US$ 110,000,000. a randomized clinical trial, we have recently demonstrated efficacy of accelerated perioperative care rehabilitation intervention after arthroplasty compared current under ideal circumstances. We do not, however, know whether these results could be reached usual circumstances healthcare practice. therefore investigated length stay implementation reduced normal...
On entering higher education students become professionally socialized, and parallel with this, stereotyping takes place, developing a more positive assessment of their own roles than those other professions. This difference between the view professions can contribute to creating cognitive social boundaries that hinder sharing knowledge, which result in poor cooperation. Interprofessional training provide good clinical expertise profession as well teach them about encouraging attitudes...
Abstract Background: Sufficient pain treatment remains a challenge after total knee arthroplasty (TKA), especially in high catastrophizing patients. Serotonergic signaling may be involved processing, but the effect of selective serotonin reuptake inhibitors on well-defined postoperative has not previously been investigated. The authors hypothesized that perioperative escitalopram would reduce TKA Methods: A 120 patients (selected using scale as preoperative screening tool) scheduled for were...
Background and purpose: Limited data exists on the implementation process safety of discharge day surgery after primary hip knee arthroplasty in a multicenter setting. We report our study protocol investigation feasibility, safety, socioeconomic aspects following across 8 fast-track centers.Patients methods: This is for prospective cohort from Center Fast-track Hip Knee Replacement. The collaboration includes centers covering 40% procedures undertaken Denmark. All patients scheduled are...
We compared the efficacy and safety of low-molecular-weight heparin with that low-dose unfractionated in prevention venous thromboembolism after total knee arthroplasty a prospective, randomized, multicenter trial. One hundred eighty-five patients were randomly assigned to two groups: ninety-two received (forty milligrams enoxaparin evening before operation once day subsequently) ninety-three (5000 international units three times thereafter). The prophylaxis was continued until bilateral...
Abstract Because the bone mineral density (BMD) in different anatomic regions is heterogenous number of women who fulfill World Health Organization definition osteopenia or osteoporosis increases with examined. The purpose this study was to investigate agreement between measurements spine, femur, forearm, and whole body following menopause. Two thousand five healthy, perimenopausal women, mean age 50.6 years, were studied using Hologic QDR-1000/W QDR-2000 densitometers. Though BMD correlated...
Background and purpose Cup failure is a recognized problem in total trapeziometacarpal (TM) joint prostheses; it may be related to poor fixation, which can revealed by radiostereometric analysis (RSA). We compared the early implant migration of cemented trapezium cups that uncemented screw cups.Patients methods In prospective, parallel-group, randomized patient-blinded clinical trial, we included 32 hands 28 patients (5 males) with mean age 58 (40–77) years Eaton stage-2 or -3 osteoarthritis...