- Ruminant Nutrition and Digestive Physiology
- Plant and fungal interactions
- Turfgrass Adaptation and Management
- Bioenergy crop production and management
- Pasture and Agricultural Systems
- Botanical Research and Chemistry
- Plant Pathogens and Fungal Diseases
- Soil Carbon and Nitrogen Dynamics
- Horticultural and Viticultural Research
- Agronomic Practices and Intercropping Systems
- Plant Pathogenic Bacteria Studies
- Rangeland and Wildlife Management
- Plant-Microbe Interactions and Immunity
- Forest Biomass Utilization and Management
- Botany and Plant Ecology Studies
- Agricultural Productivity and Crop Improvement
- Plant Toxicity and Pharmacological Properties
- Veterinary Equine Medical Research
- Autophagy in Disease and Therapy
- Agroforestry and silvopastoral systems
- Crop Yield and Soil Fertility
- Plant Taxonomy and Phylogenetics
- Legume Nitrogen Fixing Symbiosis
- Berry genetics and cultivation research
- Neonatal Respiratory Health Research
University of Alabama at Birmingham
1988-2024
Milton Keynes Council
2024
University of Kentucky
2009-2023
University of Kent
2021-2023
University of Georgia
1989-2022
Princess Alexandra Hospital
2022
The University of Queensland
2022
Royal Brisbane and Women's Hospital
2022
Augusta University Health
2022
Medway School of Pharmacy
2021
This study was undertaken to compare the ability of two guanidine compounds (aminoguanidine and methylguanidine), with different in vitro effects on NO synthase activity AGE formation, inhibit diabetic vascular dysfunction developing early after onset diabetes. In rats STZ-induced diabetes 5-wk duration, regional [125I]albumin permeation increased about two- threefold ocular tissues, sciatic nerve, aorta; general, both normalized albumin without affecting it controls. Methylguanidine only...
Cultivated forage crops are grown on almost 12 million ha the northern Great Plains. This paper reviews benefits of diversifying annual crop rotations with and highlights innovations in systems. Agronomic rotating grain include higher yields following forages (up to 13 yr one study), shifts weed population away from arable weeds, improved soil quality. Perennial legumes rotation also reduce energy requirements by adding significant amounts N soil. Soil water availability may limit extent...
Anaerobic digesters rely on the diversity and distribution of parallel metabolic pathways mediated by complex syntrophic microbial communities to maintain robust optimal performance. Using mesophilic swine waste digesters, we experimented with increased ammonia loading induce a shift from aceticlastic methanogenesis an alternative acetate-consuming pathway acetate oxidation. In comparison control observed shifts in bacterial 16S rRNA gene content functional repertoires over course digesters'...
The ability of seed-borne bacterial pathogens (Acidovorax citrulli, Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato, Xanthomonas euvesicatoria, and glycinea) to infest seeds host non-host plants (watermelon, pepper, soybean) subsequent pathogen transmission seedlings was investigated. A non-pathogenic, pigmented strain Serratia marcescens also included assess a null-interacting situation with the same plant species. Flowers were inoculated 1×106 colony forming...
Abstract The ability to suppress host macrophage apoptosis is essential for M. tuberculosis ( Mtb ) replicate intracellularly while protecting it from antibiotic treatment. We recently described that infection upregulated expression of the phosphatase PPM1A, which impairs antibacterial response macrophages. Here we establish PPM1A as a checkpoint target used by apoptosis. Overproduction suppressed Mtb- infected macrophages mechanism involves inactivation c-Jun N-terminal kinase (JNK)....
Cell-autonomous circadian clocks have emerged as temporal orchestrators of numerous biological processes. For example, the cardiomyocyte clock modulates transcription, translation, posttranslational modifications, ion homeostasis, signaling cascades, metabolism, and contractility heart over course day. Circadian are composed more than 10 interconnected transcriptional modulators, all which potential to influence cardiac transcriptome (and ultimately processes). These modulators include BMAL1...
Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the capacity to form three-dimensional organoids or ‘alveolospheres’ with type 2 alveolar epithelial cells (AEC2s). contrast L-MSCs from aged mice, young support efficient formation alveolospheres when co-cultured AEC2s. Aged demonstrated features cellular senescence,...
Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious prolonged respiratory complications survivors. Given that endoplasmic reticulum (ER) stress is a hallmark sepsis-related alveolar epithelial cell (AEC) dysfunction, we tested if AMP-activated protein kinase (AMPK) affects recovery from ER apoptosis AECs during post-bacterial infection.
Abstract Alfalfa ( Medicago saliva L.) generally does not persist well under continuous grazing. Experiments were conducted grazing to compare the persistence and regrowth potential of an alfalfa germplasm (Georgia—Grazed Collection, GA‐GC), selected for grazing, with two hay‐type (Apollo Florida 77) grazing‐type (Travois Spredor II) cultivars. The cultivars subjected continuous, heavy by beef cattle 18 weeks in each 3 yr a height 5 cm. Wire exclosures rotated at 28‐d intervals on all plots...
Differentiation of circulating monocytes into tissue-bound or tissue-resident macrophages is a critical regulatory process affecting host defense and inflammation. However, the signaling pathways that control differentiation specific distinct functional macrophage subsets are poorly understood. Herein, we demonstrate monocyte-to-macrophage controlled by Protein Phosphatase, Mg
Colonization of Xanthomonas euvesicatoria was investigated in pepper blossoms and the relationship between inoculum concentrations seed infestation determined. Inoculation resulted asymptomatic fruit. However, real-time polymerase chain reaction detected X. 39% lots assayed viable colonies were recovered from 35% them. Successful transmission occurred 16% tested. In a separate experiment, reached populations up to 1 × 10 5 CFU/blossom on stigmas 96 h after inoculation. Bacteria colonized...
Alfalfa ( Medicago saliva L.) has been predominately used as a hay crop in North America and most cultivars do not persist under grazing. The objectives of this research were to determine if grazing tolerance could be improved within alfalfa population shifts that occurred during selection. original selected populations ‘Apollo’, ‘Florida 77’, ‘Alfagraze’, ‘Spredor II’, ‘Travels’ evaluated central Georgia 17 22 wk continuous close by beef cattle for 2 yr. Experiments I II comprised two...
Abstract Improvements in alfalfa ( Medicago sativa L.) forage nutritive value through reduction lignin content have the potential to increase economic returns when it is fed dairy cattle, either as a pure species or mixture with perennial grasses. Our objective was assess yield and of reduced‐lignin monoculture binary mixtures grass. Studies were seeded spring 2016 Ithaca, NY, Lexington, KY, Rosemount, MN, harvested 2016, 2017 2018. WL 355.RR Hx14376 stands festulolium [ Festulolium...
Inadequate seed supplies of adapted blue grama [ Bouteloua gracilis (H.B.K.) Lag. ex Steud.] and little bluestem Schizachyrium scoparium (Michx.) Nash.] cultivars limits the use these two species in northern Great Plains Western Canada. This study examined variation yield traits 11 14 plant collections obtained from southern Manitoba, Canada to facilitate development improved germplasm species. Measurements including harvested air‐dried biomass, culm number, seedhead yield, caryopsis weight,...