Neurotransmitters are chemicals that act as messengers in the synaptic transmission process. They essential for human health and any imbalance their activities can cause serious mental disorders such Parkinson’s disease, schizophrenia, Alzheimer’s disease. Hence, monitoring concentrations of various neurotransmitters is great importance studying diagnosing illnesses. Recently, many researchers have explored use unique materials developing biosensors both vivo ex neurotransmitter detection. A...

To describe the extraosseous blood supply of tibia and how distal is influenced by different plating techniques.Microdissection cadaveric adult hip disarticulation specimens following sequential arterial injections india ink Ward's Blue Latex was performed. Readily identifiable arterioles measured approximately 0.5 mm in diameter. Their artery origin identified, their position along medial, lateral, posterior aspects documented relative to tibial plafond. Additionally, six matched pairs...

This paper presents a fully inkjet-printed electrochemical sensor on which consists of carbon nanotube-printed working, reference, and counter electrodes. The proposed technique aims at low-cost disposable paper-based sensors. First, nanotube (CNT) ink was directly paper, forming conductive network. Additionally, hydrophobic barrier patterned to limit the absorption liquid designed area. inkjet printing method allows for rapid patterning electrodes resulting in simple effective sensor. sheet...

Recently, inkjet-printing has gained increased popularity in applications such as flexible electronics and disposable sensors, well wearable sensors because of its multifarious advantages. This work presents a novel, low-cost immobilization technique using for the development an aptamer-based biosensor detection lysozyme, important biomarker various disease diagnosis. The strong affinity between carbon nanotube (CNT) single-stranded DNA is exploited to immobilize aptamers onto working...

Lab-on-a-chip technology offers an ideal platform for low-cost, reliable, and easy-to-use diagnostics of key biomarkers needed early screening diseases other health concerns. In this work, a graphene field-effect transistor (GFET) functionalized with target-binding aptamers is used as biosensor the detection thrombin protein biomarker. Furthermore, GFET integrated microfluidic device enhanced sensing performances in terms limit, sensitivity, continuous monitoring. Under platform, picomolar...

A water-based carbon nanotube ink for inkjet printing was prepared by dispersing single-walled nanotubes (SWCNT) with sodium n-dodecyl sulfate (SDS), an anionic surfactant. standard Hewlett-Packard (HP) printer employed to deposit the onto a transparency film in order form conductive electrodes. sheet resistance as low 132 Ω/□ obtained electrodes, which is one of lowest values ever reported. Using inkjet-printed and screen-printed silver epoxy, cheap, flexible, disposable electrochemical...

Aptamer-immobilized graphene field-effect transistors (GFETs) have become a well-known detection platform in the field of biosensing with various biomarkers such as proteins, bacteria, virus, well chemicals. A conventional aptamer immobilization technique on involves two-step crosslinking process. In first step, pyrene derivative is anchored onto surface and, second an amine-terminated crosslinked to backbone EDC/NHS (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide...

Study Design. A prospective clinical trial to study the radiographic parameters and functional outcome in patients undergoing spinal osteotomy. Objectives. To determine whether correction of specific is associated with improved outcome. Summary Background Data. Although vertebral osteotomies have been shown improve deformity, no reports studied improvement Methods. Eighty-three fixed sagittal and/or coronal deformity were followed over a 7-year period. Patients evaluated clinically...

Selective and rapid detection of biomarkers is utmost importance in modern day health care for early stage diagnosis to prevent fatal diseases infections. Among several protein biomarkers, the role lysozyme has been found be especially important human immune system bacterial infections other chronic disease such as bronchopulmonary dysplasia. Thus, real-time monitoring concentration a body can pave facile route warning potential Here, we present first time label-free sensor that selective...

Serotonin (5-HT) is a critical neurotransmitter involved in many neuronal functions, and 5-HT depletion has been linked to several mental diseases. The fast release clearance of serotonin the extracellular space, low analyte concentrations, multitude interfering species make detection challenging. This work presents an electrochemical aptamer-based biosensing platform that can monitor continuously with high sensitivity selectivity. Our sensor showed response time approximately 1 min step...

This paper presents a novel method to selectively detect hydrogen peroxide using chemiresistive polyaniline nanowire network. The nanowires modified with silver catalytic nanoparticles were demonstrated give selective responses by changing the conductivity of polyaniline. proposed mechanism for selectivity in H2O2 sensing is based on reaction between and which generates hydroxide ions water influence effect was confirmed characterizing relationship amount catalysts current response. results...

Abstract With recent advances in biotechnology, mammalian cells are used biopharmaceutical industries to produce valuable protein therapeutics and investigated as effective therapeutic agents permanently degenerative diseases cell based therapy. In these exciting actively expanding fields, a reliable, efficient, affordable platform culture on large scale is one of the most vital necessities. To maintain very population anchorage‐dependent cells, microcarrier‐based stirred tank bioreactor...

Glutamate (Glu) and histamine (His) are two major neurotransmitters that play many critical roles in brain physiological functions neurological disorders. Therefore, specific sensitive monitoring of Glu His is essential the diagnosis treatment various mental health neurodegenerative Both being non-electroactive species, direct electrochemical detection has been challenging. Herein, we report a stimuli-responsive polymer-based biosensor for His. The target receptors consist linear chain...

Commercially available bulk niobium diselenide (NbSe2) reduced into nanomaterials upon exfoliation typically contains oxide and carbide impurities. Liquid-phase exfoliated two-dimensional (2D) nanosheets of NbSe2 obtained from powders provide high charge mobility large surface area but become self-passivated chemically inert as the presence impurities makes them behave more semimetallic. In this article, we report effects inherent liquid-phase 2D (intended to be integrated supercapacitor...

The use of highly cross-linked molecularly imprinted polymers as a synthetic target receptor has the limitations restricted accessibility to binding sites, resulting in slow response time. Moreover, such artificial receptors often require additional transduction mechanisms translate events into measurable signals. Here, we propose development single-chain stimuli-responsive templated polymer, without using any covalent interchain cross-linkers, recognition element. synthesized polymer chain...