A5101501781- Inflammatory Bowel Disease
- Pharmacological Effects of Natural Compounds
- RNA Research and Splicing
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Helicobacter pylori-related gastroenterology studies
- Hippo pathway signaling and YAP/TAZ
- MicroRNA in disease regulation
- Pluripotent Stem Cells Research
- Simulation and Modeling Applications
- Pancreatitis Pathology and Treatment
- Adolescent and Pediatric Healthcare
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Advanced Sensor and Control Systems
- Microscopic Colitis
- Advanced Measurement and Detection Methods
Chengdu University of Traditional Chinese Medicine
2016-2022
Chengdu University
2020
Abstract Accumulating evidence suggests that long non‐coding RNA s (lnc s) are playing critical roles in neurogenesis, yet the underlying molecular mechanisms remain largely elusive. Neurite outgrowth is an early step neuronal differentiation and regeneration. Using vitro of neuroblastoma‐derived Neuro‐2a (N2a) cell as a model, we performed expression profiling to identify lnc putatively relevant for neurite outgrowth. We identified Metastasis‐associated lung adenocarcinoma transcript 1...
Evidence suggest that overexpression of hypoxia-inducible factor-1α (HIF-1α) is linked to multidrug resistance epilepsy. Here we explored whether aberrant expression HIF-1α regulated by miRNAs. Genome-wide microRNA profiling was performed on temporal cortex resected from mesial lobe epilepsy (mTLE) patients and age-matched controls. miRNAs are putative regulator were predicted via target scan confirmed real-time quantitative polymerase chain reaction (RT-qPCR). Mimics or miRNA morpholino...
Abstract The cAMP response element‐binding (CREB) protein is a member of the CREB/activating transcription factor family that activated by various extracellular stimuli. It has been shown CREB‐dependent stimulation plays key role in neuronal differentiation and plasticity, but underlying mechanisms remain largely elusive. Here, we show Yes‐associated (YAP) direct target induced CREB upon retinoic acid (RA)‐induced neurite outgrowth stimuli N2a cells. Interestingly, YAP knockout using...
The roll control is fighter aerobatic training subjects, often. Usually includes the dive, and barrel other operations. According to maneuver characteristics, based on finite element method complete analysis of flow field wing. solve basic idea divide which has be used in discretization procedure were established equilibrium equation each unit, accordance with node displacement compatibility conditions conditions, whole system established.
Abstract Background : Enteric-coated HuDi capsules（HuDi）have been approved for the treatment of ulcerative colitis (UC) in China. In this clinical trial, we objectively evaluated efficacy and safety combined with enteric-coated mesalazine tablets active UC. Methods A total 355 patients from 18 hospitals China were randomly divided into group, tablet group (mesalazine group) or randomized, controlled double-blinding double-modeling methods. The followed every two weeks reexamined by endoscopy...