Jacob Fromm

ORCID: 0000-0003-1737-8803
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About
Contact & Profiles
Research Areas
  • Research on Leishmaniasis Studies
  • Cynara cardunculus studies
  • Trypanosoma species research and implications

University of Kansas
2022

Human leishmaniasis is an infectious disease caused by Leishmania protozoan parasites. Current chemotherapeutic options against the deadly have significant limitations. The ergosterol biosynthetic pathway has been identified as a drug target in Leishmania. However, remarkable differences efficacy of antifungal azoles that inhibit biosynthesis reported for treatment leishmaniasis. To better understand sterol and elucidate mechanism underlying differential azoles, we developed new LC-MS/MS...

10.1016/j.ijpddr.2022.07.003 article EN cc-by-nc-nd International Journal for Parasitology Drugs and Drug Resistance 2022-08-15
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