To investigate possible correlations between vitreous and/or serum levels of platelet-derived growth factor isoforms (PDGF-AA, -AB and -BB) with parameters associated non-proliferative diabetic retinopathy (NPDR) clinically significant macula oedema (CSMO); to compare the results relevant regarding vascular endothelial (VEGF), which is an established affecting NPDR.Fifteen patients NPDR, 31 proliferative (PDR) 15 non-diabetic were included in study. Vitreous samples obtained during...

Purpose: We investigated possible correlations between vitreous and/or serum levels of platelet derived growth factor isoforms (PDGF-AA, -AB, -BB) with parameters associated proliferative diabetic retinopathy (PDR), and compared the results to vascular endothelial (VEGF), which is an established affecting PDR. Methods: Thirty-one patients PDR 15 non-diabetic were included in study. Vitreous samples obtained during vitrectomy. PDGF-AA, -BB, as well VEGF, measured by enzyme-linked...

To evaluate the efficacy of self-retaining bicanaliculus stents when used as an adjunct to 3-snip punctoplasty in comparison with standard procedure between fellow eyes.Prospective, randomized, comparative study. Thirty-two eyes 16 consecutive patients acquired, nontraumatic stenosis proximal lacrimal duct were randomly distributed into 2 equal study groups. Lower punctal was a prerequisite. Group A (16 eyes) received simple punctoplasty, while group B underwent modified combined insertion...

The purpose of this study was to determine whether application a risk stratification system during preoperative assessment cataract patients and subsequent allocation surgeons with matching experience may reduce intraoperative complications.Nine hundred fifty-three consecutive (1109 eyes) undergoing phacoemulsification surgery were assigned two groups, ie, group A (n = 498 patients, 578 B 455 531 eyes). Patients from allocated varying only rough estimate the complexity their surgery. three...

BackgroundThe aim of this study was to develop MNREAD acuity charts in the Greek language (MNREAD‐GR) and establish their repeatability a normal‐sighted population.MethodsOne hundred eighty sentences were constructed based on design principles Minnesota Low Vision Reading Test. The software used validate them for width adjusted parameters non‐Latin characters (MNTest‐GR) width‐validated then checked literacy by two teachers. Pilot testing followed 20 adults groups children. Subsequently,...

To determine the time-dependent toxicity of Trypan blue at 0.06% concentration in cultured human trabecular meshwork cells.Human cells vitro were exposed to and acute was evaluated. Cells for 5, 30, 60 s 15, min a commercially available preparation (Vision Blue; DORC International Zuidland, The Netherlands). Morphology observed by phase-contrast microscopy cell viability measured using Hoechst 33342 (Intergen; Purchase, NY, USA) propidium iodide assays percentage living dead...

To evaluate the efficacy of pars plana vitrectomy in conjunction with intraoperative perfluoro-n-octane (PFO) use as initial treatment retinal detachment (RD) multiple breaks located at various distances from ora serrata.Twenty-two consecutive eyes (15 phakic, 2 aphakic, and 5 pseudophakic) presenting RD tears underwent primary vitrectomy, PFO reattachment, transcleral cryopexy or endolaser breaks, PFO/air exchange, final injection 18% perfluoropropane (C3F8). Scleral buckles were not used....

To evaluate the effect of laser photocoagulation for diabetic macular oedema (DME) on patients' Vision Related Quality Of Life (VR-QOL) and to investigate associations between changes in self reported VR-QOL visual acuity following application treatment.Prospective cohort study 55 subjects who underwent treatment DME. Eligible patients with no history previous self-administered 51-item field-test version National Eye Institute Visual Function Questionnaire (NEI-VFQ) prior 3 months last...

We investigated the activity of matrix metalloproteinase (MMP)-2 and -9 their latent pro-forms (proMMP-2, -9), protein levels MMP-1, -3, -8 tissue inhibitor MMPs (TIMP)-1 in subretinal fluid (SRF) vitreous patients with rhegmatogenous retinal detachment (RRD). Potential correlations proliferative vitreoretinopathy (PVR) grade were determined.Thirty-seven SRF 32 samples from RRD nine human organ donors (controls), collected assayed for -8/TIMP-1 using enzyme-linked immunosorbent assay...

A prospective interventional pilot study was performed to estimate the effect of ranibizumab injection on clinical and histological picture primary pterygium.Five patients with pterygia received a single subconjunctival (0.3 mg), whereas 5 nontreated served as controls. The treated were surgically removed 3 days, 1 week, 2 weeks, month, months after injection, respectively. Digital photographs taken immediately before week after, day operation.Ranibizumab well tolerated by all patients, no...

To investigate the effect of binocularity on long-term visual acuity in patients who have undergone bilateral implantation a presbyopia-correcting diffractive multifocal intraocular lens (IOL).Twenty (9 men and 11 women) with an average age 70 ± 7 years (range: 56 to 78 years) underwent IOL (AcrySof IQ ReSTOR IOL, SN60D3; Alcon Laboratories, Inc., Fort Worth, TX). Uncorrected was measured monocularly binocularly 26 6 months following second eye 17 40 months) using University Crete...

Purpose: Central serous chorioretinopathy (CSCR) manifests as neurosensory detachment of the macula and can be attributed to focal or multifocal leakage in retinal pigment epithelium (RPE). Fibrin accumulation subretinal space is an unusual heretofore unreported visually damaging manifestation severe CSCR. Methods: The patient was followed up with use biomicroscopy, fluorescein angiography, optical coherence tomography (OCT). Results: A 32-year-old woman referred our department complaining...

Purpose To study postoperative macular thickness fluctuations measured by spectral-domain optical coherence tomography (SD-OCT) and to investigate a potential correlation among edema (ME) incidence, cumulative dissipated energy (CDE) released during phacoemulsification, vitreoretinal interface status. Methods This is prospective, cross-sectional of 106 cataract patients with no disorder who underwent phacoemulsification. Best-corrected visual acuity measurement, slit-lamp examination, OCT...

Purpose To evaluate the safety and efficacy of oral steroids when combined with long-term azathioprine (AZA) orbital radiotherapy in patients active thyroid-related restrictive myopathy. Methods A total 88 from adnexal outpatient clinics Bristol Eye Hospital, UK, 2 nd Department Ophthalmology at Aristotle University Thessaloniki, Greece, were enrolled a retrospective, twin-center study. All diagnosed thyroid eye disease concomitant Treatment included AZA, low-dose steroids, (20 Gy). Clinical...

Purpose. To evaluate and compare the efficacy of two different training methods in resident-performed phacoemulsification surgery. Methods. 502 eyes 467 patients who underwent were included study by reviewing their medical records. Residents allocated into groups according to method applied during cataract surgery; Group A residents that trained with “step-by-step” B those “one-step” method. Primary outcome was incidence main complications, defined as posterior capsular ruptures and/or...