A5044329991- Tuberculosis Research and Epidemiology
- HIV/AIDS Research and Interventions
- Healthcare Systems and Reforms
- Adolescent Sexual and Reproductive Health
- Health Policy Implementation Science
- Viral Infections and Vectors
- Sex work and related issues
- Global Public Health Policies and Epidemiology
- HIV/AIDS drug development and treatment
- Global Maternal and Child Health
- Pharmaceutical studies and practices
- Chronic Disease Management Strategies
- Pneumocystis jirovecii pneumonia detection and treatment
- Neutropenia and Cancer Infections
- HIV Research and Treatment
- Viral Infections and Outbreaks Research
- Sepsis Diagnosis and Treatment
- Disaster Management and Resilience
- HIV/AIDS Impact and Responses
- Health Systems, Economic Evaluations, Quality of Life
Kilimanjaro Christian Medical Centre
2021-2025
Ministry of Health, Community Development, Gender, Elderly and Children
2025
Abstract Background Marburg virus disease (MVD) is a deadly illness caused by the zoonotic virus, which has led to outbreaks with fatality rates up 100% in some African countries. On March 21, 2023, Tanzania had its first MVD outbreak, resulting nine cases and six deaths, leading rate of 66.7%. Following that, Risk Communication Community Engagement (RCCE) approach was promptly initiated create community awareness regarding MVD. A descriptive cross-sectional assessment conducted May 2023...
To determine patients' acceptability, satisfaction and adherence to shorter all-oral multidrug-resistant tuberculosis (MDR-TB) regimen in Tanzania. A two-phase cross-sectional study with data collected within 6 months of Removed Injectable modified Short-course regimens for EXpert MDR-TB (RISE) implementation the second phase 15 using same reference populations. 18 health facilities across eight regions Rifampicin-resistant TB/MDR-TB patients enrolled RISE study. We assessed an interval...
Monitoring resistance to first line Antiretroviral therapy (ART) is crucial in preventing accumulation of viral mutations following the implementation World Health Organization "treat all" initiative. We estimated rate and predictors virological treatment failure among adults living with HIV/AIDS Dar es Salaam, Tanzania.A retrospective cohort study involving aged 18 above receiving ART as Salaam between 2016 2018 were recruited using multistage random sampling. Clinical laboratory data...
Abstract Background Fishing communities are a subpopulation burdened by human immunodeficiency virus (HIV), mainly due to their mobility and cash income access. Strategies mitigate the spread of HIV in fishing have varying outcomes. We conducted study determine prevalence HIV, recent infection associated factors among at Lake Victoria Tanzania. Methods cross-sectional first quarter 2019. The participants' information was collected using structured questionnaire. Blood samples were screened...
Introduction Sub-Saharan Africa shoulders the highest burden of global sepsis and associated mortality. In high HIV tuberculosis (TB) prevalent settings such as sub-Saharan Africa, TB is leading cause sepsis. However, anti-TB therapy often delayed may not achieve adequate blood concentrations in patients with Accordingly, this multisite randomised clinical trial aims to determine whether immediate and/or increased dose improves 28-day mortality for participants Tanzania or Uganda. Methods...
Background: Many evidence-based health interventions, particularly in low-income settings, have failed to deliver the expected impact. We designed an Adaptive Diseases Control Expert Programme Tanzania (ADEPT) address systemic challenges care delivery and examined feasibility, acceptability effectiveness of model using tuberculosis (TB) diabetes mellitus (DM) as a prototype. Methods: This was effectiveness-implementation hybrid type-3 design that implemented Dar es Salaam, Iringa Kilimanjaro...
Introduction Tanzania is adapting a shortened injectable-free multidrug resistant tuberculosis (MDR-TB) regimen, comprising new drugs such as bedaquiline and delamanid repurposed clofazimine linezolid. The regimen implemented using pragmatic prospective cohort study within the National TB Leprosy Programme accompanied by process evaluation. evaluation aims to unpack implementation processes, their outcomes moderating factors in order understand clinical effectiveness of regimen. This...
Introduction: Identifying people exposed to HIV is critical towards achieving the UNAIDS 90-90-90 goals for epidemic control. The first 90 in Tanzania at 53% and yet factors partner's elicitation care providers are poorly understood. objective of this study was determine predictors among index positive clients.
Poor quality of health care services remains an important challenge in delivery systems. Here, we validate clinical audit tools and describe results selected standards related to communicable disease (CD) non-communicable (NCD) integration at the primary level.