A5058403612- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Global Maternal and Child Health
- HIV/AIDS Impact and Responses
- HIV/AIDS drug development and treatment
- Sex work and related issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Ethics in Clinical Research
- COVID-19 diagnosis using AI
- Reproductive Health and Contraception
- Food Security and Health in Diverse Populations
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Viral Infections and Outbreaks Research
- Ocular Diseases and Behçet’s Syndrome
- Ocular Oncology and Treatments
- Adolescent and Pediatric Healthcare
- Global Cancer Incidence and Screening
- Cervical Cancer and HPV Research
- SARS-CoV-2 and COVID-19 Research
- Travel-related health issues
- COVID-19 epidemiological studies
- Health Policy Implementation Science
Liverpool School of Tropical Medicine
2017-2025
Centre for Sexual Health and HIV AIDS Research
2016-2025
University of KwaZulu-Natal
2017
University of Zimbabwe
2011-2016
University College London
2011-2013
University of Zimbabwe-University of California San Francisco
2012
The current study identifies young people's preferences for HIV self-testing (HIVST) delivery, determines the relative strength of and explores underlying behaviors perceptions to inform youth-friendly services in southern Africa.A mixed methods design was adopted Malawi Zimbabwe includes focus group discussions, in-depth interviews discrete choice experiments.The conducted during formative phase cluster-randomized trials oral-fluid HIVST distribution. Young people aged 16-25 years were...
The prevalence of undiagnosed HIV is declining in Africa, and various testing approaches are finding lower positivity rates. In this context, the epidemiological impact cost-effectiveness community-based self-testing (CB-HIVST) unclear. We aimed to assess different sub-populations across scenarios characterized by adult antiretroviral treatment programmes sub-Saharan Africa.The synthesis model was used address aim. Three were considered for CB-HIVST: (i) women having transactional sex (WTS);...
Background Providing HIV testing at health facilities remains the most common approach to ensuring access treatment and prevention services for millions of undiagnosed HIV-infected individuals in sub-Saharan Africa. We sought explore costs providing these across three southern African countries with high burden. Methods Primary costing studies were undertaken 54 (HTS) Malawi, Zambia Zimbabwe. Routinely collected monitoring evaluation data extracted estimate per individual tested HIV-positive...
HIV self-testing (HIVST) is recommended by the World Health Organization in addition to other testing modalities increase uptake of testing, particularly among harder-to-reach populations. This study provides first empirical evidence costs door-to-door community-based HIVST distribution Malawi, Zambia and Zimbabwe.HIVST kits were distributed 71 sites across Zimbabwe from June 2016 May 2017. Programme expenditures, supplemented on-site observation monitoring evaluation data used estimate...
Abstract Introduction New HIV testing strategies are needed to reach the United Nations’ 90‐90‐90 target. self‐testing ( HIVST ) can increase uptake, but users’ perspectives on optimal models of distribution and post‐test services uncertain. We used discrete choice experiments DCE s) explore impact service characteristics uptake along cascade. Methods s a quantitative survey method that present respondents with repeated choices between packages characteristics, estimate relative strengths...
<sec> <title>BACKGROUND</title> Sex workers (SW) are at risk of acquiring HIV infections. Despite this, SW have low uptake relevant preventive measures such as pre-exposure prophylaxis (PrEP). Community-based programs that make PrEP convenient and accessible potential to drive continuation reduce risk. </sec> <title>OBJECTIVE</title> This paper describes the co-development piloting TOPAZ study – which encompasses an intervention providing with opportunity access refills through pharmacies in...
Control of infectious diseases is a global health priority and target the 2015-2030 Sustainable Development Goals (SDGs). Community participation fundamental to advancing primary care meeting SDGs. We conducted mixed-methods systematic literature review quantitative qualitative evidence understand health, social, economic impact community-led strategies for communicable disease prevention management in low- middle- income countries. searched seven electronic databases through 31 December,...
Abstract Introduction The ability to achieve an accurate test result and interpret it correctly is critical the impact effectiveness of HIV self‐testing (HIVST). Simple easy‐to‐use devices, instructions for use (IFU) other support tools have been shown be key good performance in sub‐Saharan Africa may highly contextual. objective this study was explore utility cognitive interviewing optimizing local understanding manufacturers’ IFUs HIVST result. Methods Functionally literate antiretroviral...
To present findings from implementation and scale-up of human immunodeficiency virus (HIV) self-testing programmes for female sex workers in Malawi Zimbabwe, 2013-2018.In we carried out formative research to assess the acceptability accuracy HIV self-testing. During evaluated workers' preferences for, feasibility of, distribution test kits before programme was scaled-up. In Malawi, conducted a rapid ethnographic assessment explore context needs resources available, leading workshop define...
Abstract Background Qualitative research networks (QRNs) bring together researchers from diverse contexts working on multi-country studies. The may themselves form a consortium or contribute to wider agenda within with colleagues other disciplines. purpose of QRN is ensure robust methods and processes that enable comparisons across contexts. Under the Self-Testing Africa (STAR) initiative REACHOUT project community health systems, QRNs were established, bringing countries coordinate...
HIV self-testing (HIVST) requires linkage to post-test services maximise its benefits. We evaluated effect of supply-side incentivisation on following community-based HIVST and time-trends in facility-based antiretroviral therapy (ART) initiations.
Couples' HIV testing and counselling (CHTC) is associated with greater engagement prevention care than individual cost-effective, but uptake remains suboptimal. Initiating discussion of CHTC might result in distrust between partners. Offering incentives for could change the focus pre-test discussion. We aimed to determine impact on couples case diagnosis rural Zimbabwe.In this cluster-randomised trial, 68 communities (the clusters) four districts receiving mobile services were randomly...
The current research identifies key drivers of demand for linkage into care following a reactive HIV self-test result in Malawi and Zambia. Preferences are explored among the general population groups such as HIV-positive individuals adolescents.We used discrete choice experiments (DCEs) embedded representative household surveys to quantify relative strength preferences various services characteristics.The DCE was designed on basis literature review qualitative studies. Data were collected...
<h3>Importance</h3> HIV self-testing is a promising approach for increasing awareness of status in sub-Saharan Africa, particularly Zimbabwe, where prevalence 13%. Evidence lacking, however, on the optimal pricing policies and delivery strategies maximizing effect self-testing. <h3>Objective</h3> To assess demand among adults priority-population subgroups under alternative distribution strategies. <h3>Design, Setting, Participants</h3> This randomized clinical trial recruited study...
Simple and easy to use kits for SARS-Cov-2 self-testing during epidemic waves are needed optimize diagnostic capacity in low- middle-income countries. available, but application of these novel technologies is less understood low contexts. We investigated the ability understand perform instructions (IFUs) STANDARD Q COVID-19 Ag Test (SD Biosensor) Panbio Rapid Device (Abbott Diagnostics) anterior nares (AN) nasal self-sampling rural urban Malawi. Qualitative research methods using iterative...
Background COVID-19 testing is critical for identifying cases to prevent transmission. self-testing has the potential increase diagnostic capacity and expand access hard-to-reach areas in low-and-middle-income countries. We investigated feasibility acceptability of self-sampling using SARS-CoV-2 Antigen-Rapid Diagnostic Tests (Ag-RDTs). Methods From July 2021 February 2022, we conducted a mixed-methods cross-sectional study examining Standard Q Panbio Ag Rapid Test Device Urban rural...
Provider-initiated HIV testing and counselling (PITC) is widely recommended to ensure timely treatment of HIV. The Zimbabwe Ministry Health introduced PITC in 2007. We aimed evaluate institutional capacity implement investigate patient health care worker (HCW) perceptions the programme. Purposive selection institutions was conducted among those providing PITC. Study procedures included 1) assessment implementation using a semi-structured questionnaire; 2) in-depth interviews with patients...
Abstract Introduction Despite improvements in prevention of mother‐to‐child transmission (PMTCT) HIV outcomes, there remain unacceptably high numbers transmissions (MTCT) HIV. Programmes and research collect multiple sources PMTCT data, yet this data is rarely integrated a systematic way. We conducted integration exercise to evaluate the Zimbabwe national programme derive lessons for strengthening implementation documentation. Methods used from four sources: research, Ministry Health Child...
Introduction As countries approach the UNAIDS 95-95-95 targets, there is a need for innovative and cost-saving HIV testing approaches that can increase coverage in hard-to-reach populations. The Self-Testing Africa-Initiative distributed self-test (HIVST) kits using unincentivised counsellors across 31 public facilities Malawi, South Africa, Zambia Zimbabwe. HIVST was either through secondary (partner’s use) distribution alone or primary (own approaches. Methods We evaluated costs of adding...