Getrude Ncube

ORCID: 0000-0002-8873-8901
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • Adolescent Sexual and Reproductive Health
  • Genital Health and Disease
  • HIV, Drug Use, Sexual Risk
  • Female Genital Mutilation/Cutting Issues
  • Ethics and Legal Issues in Pediatric Healthcare
  • HIV Research and Treatment
  • Urologic and reproductive health conditions
  • Urological Disorders and Treatments
  • Sex work and related issues
  • HIV/AIDS Impact and Responses
  • Global Maternal and Child Health
  • Poverty, Education, and Child Welfare
  • Reproductive tract infections research
  • Mobile Health and mHealth Applications
  • HIV/AIDS drug development and treatment
  • Intimate Partner and Family Violence
  • Health Literacy and Information Accessibility
  • HIV-related health complications and treatments
  • Adolescent and Pediatric Healthcare
  • Urban and Rural Development Challenges
  • Food Security and Health in Diverse Populations
  • Focus Groups and Qualitative Methods
  • Vaccine Coverage and Hesitancy
  • ICT in Developing Communities

Ministry of Health and Child Welfare
2015-2025

Biomedical Research and Training Institute
2014

Background Understanding the perspectives and preferences of clients eligible for pre-exposure prophylaxis (PrEP) is essential to designing programs that meet clients' needs. To date, most PrEP in limited-resource settings have been implemented by partner organizations specific target populations, but government Zimbabwe aims make available broader population at substantial risk public sector clinics. However, there limited information on general about Zimbabwe. Methods A qualitative study...

10.1371/journal.pone.0227632 article EN cc-by PLoS ONE 2020-01-13

The prevalence of undiagnosed HIV is declining in Africa, and various testing approaches are finding lower positivity rates. In this context, the epidemiological impact cost-effectiveness community-based self-testing (CB-HIVST) unclear. We aimed to assess different sub-populations across scenarios characterized by adult antiretroviral treatment programmes sub-Saharan Africa.The synthesis model was used address aim. Three were considered for CB-HIVST: (i) women having transactional sex (WTS);...

10.1002/jia2.25243 article EN cc-by Journal of the International AIDS Society 2019-03-01

Several countries in southern Africa have made significant progress towards reaching the Joint United Nations Programme on HIV/AIDS goal of ensuring that 90% people living with HIV are aware their status. In Zimbabwe, this "first 90" was estimated at 73% 2016. To reach remaining who undiagnosed infection, Zimbabwe Ministry Health and Child Care has been promoting index testing partner notification services (PNS). We describe implementation PNS under Treatment (ZHCT) project resulting uptake,...

10.1002/jia2.25321 article EN cc-by Journal of the International AIDS Society 2019-07-01

Abstract Introduction HIV self‐testing (HIVST) was first proposed as an additional option to standard testing services in the 1980s. By 2015, two years after HIVST kit approved for American market and year which Unitaid invested “HIV Self‐Testing AfRica (STAR) Initiative,” remained unexplored with negligible access low‐ middle‐income countries (LMIC). However, rapid progress had been made. This commentary outlines interlinked market, regulatory policy barriers that inhibited product...

10.1002/jia2.25249 article EN cc-by Journal of the International AIDS Society 2019-03-01

Zimbabwe has a high human immunodeficiency virus (HIV) burden. It is therefore important to scale up HIV-testing and counseling (HTC) as gateway HIV prevention, treatment care.To determine factors associated with being HIV-tested among adult men women in Zimbabwe.Secondary analysis was done using data from 7,313 6,584 who completed interviewer-administered questionnaires provided blood specimens for testing during the Demographic Health Survey (ZDHS) 2010-11. Factors ever were determined...

10.1371/journal.pone.0147828 article EN public-domain PLoS ONE 2016-01-25

HIV self-testing (HIVST) is recommended by the World Health Organization in addition to other testing modalities increase uptake of testing, particularly among harder-to-reach populations. This study provides first empirical evidence costs door-to-door community-based HIVST distribution Malawi, Zambia and Zimbabwe.HIVST kits were distributed 71 sites across Zimbabwe from June 2016 May 2017. Programme expenditures, supplemented on-site observation monitoring evaluation data used estimate...

10.1002/jia2.25255 article EN cc-by Journal of the International AIDS Society 2019-03-01

Abstract Introduction Sisters with a Voice (Sisters) , programme providing community‐led differentiated HIV prevention and treatment services, including condoms, testing, pre‐exposure prophylaxis (PrEP) antiretroviral therapy linkage for sex workers, reached over 26,000 female workers (FSW) across Zimbabwe in 2020. Zimbabwe's initial Covid “lockdown” March 2020 associated movement restrictions interrupted clinical service provision 6 weeks, particularly mobile clinics, triggering the...

10.1002/jia2.25813 article EN cc-by Journal of the International AIDS Society 2021-10-01

Abstract Background In Kenya, South Africa, and Zimbabwe, oral pre-exposure prophylaxis (PrEP) is recommended for adolescent girls young women (AGYW) at high risk of HIV. Health providers play a critical role in the uptake effective use sexual reproductive health services; however, few published studies have explored providers’ attitudes toward experiences delivering PrEP to AGYW. Methods We conducted cross-sectional qualitative study, interviewing 113 36 public, private, nongovernmental...

10.1186/s12913-021-06978-0 article EN cc-by BMC Health Services Research 2021-10-18

The Dapivirine vaginal ring (DPV-VR) is an intravaginal silicone that delivers antiretroviral drug (Dapivirine) directly to tissues for 28 days. This protects women against HIV during the receptive sex at site of potential infection. In 2021, WHO recommended DPV as additional prevention method high-risk with other approaches. With its discreet usage and disposal, DPV-VR has become a preferred among young in Sub-Saharan Africa prevalent patriarchal social structure prevents from making...

10.1371/journal.pgph.0004081 article EN cc-by PLOS Global Public Health 2025-03-31

HIV self-testing (HIVST) requires linkage to post-test services maximise its benefits. We evaluated effect of supply-side incentivisation on following community-based HIVST and time-trends in facility-based antiretroviral therapy (ART) initiations.

10.1136/bmjgh-2020-003866 article EN cc-by-nc BMJ Global Health 2021-07-01

Children living with HIV who are not diagnosed in infancy often remain undiagnosed until they present advanced disease. Provider-initiated testing and counselling (PITC) health facilities is recommended for high-HIV-prevalence settings, but it unclear whether this approach sufficient to achieve universal coverage of testing. We aimed investigate the change community burden infection among older children adolescents following implementation PITC Harare, Zimbabwe.Over course 2 years (January...

10.1371/journal.pmed.1002360 article EN cc-by PLoS Medicine 2017-07-25

Background Targeted HIV testing strategies are needed to reach remaining undiagnosed people living with and achieve the UNAIDS’ 95-95-95 goals for 2030. self-testing (HIVST) can increase uptake of among young people, but user perspectives on novel distribution methods uncertain. We assess acceptability, perceived challenges, recommendations adult lay counselor-led campus-based HIVST delivery tertiary school students aged 18–24 years in Zimbabwe. Methods purposively sampled participants from...

10.1371/journal.pone.0253745 article EN cc-by PLoS ONE 2021-06-29

Background New HIV infections among sub-Saharan Africa's adolescent girls and young women (AGYW, ages 15–24) greatly exceed those of their male peers. In addition, AGYW tend to acquire at a much earlier age. Understanding the factors associated with infection in could inform effective prevention treatment interventions for these populations sexual partners. Methods This qualitative study, conducted October-November 2016, was follow on quantitative survey that sought characterize partners...

10.1371/journal.pone.0194732 article EN public-domain PLoS ONE 2018-03-22

Abstract Background Many southern African countries are nearing the global goal of diagnosing 90% people with HIV by 2020. In 2016, 84 and 86% knew their status in Malawi Zimbabwe, respectively. However, gaps remain, particularly among men. We investigated awareness use of, willingness to self-test for explored sociodemographic associations before large-scale implementation. Methods pooled responses from two first cross-sectional Demographic Health Surveys include self-testing (HIVST)...

10.1186/s12889-020-08855-7 article EN cc-by BMC Public Health 2020-05-25

Background: The emergence of antiretroviral therapy (ART) transformed HIV from a terminal illness to chronic disease. However, limited access health services remains one many barriers service utilisation by people living with (PLHIV) in low-resource settings. goal this study was describe the two provinces Zimbabwe.Methods: A qualitative descriptive conducted PLHIV and village workers (VHW) eight districts within provinces. Convenience sampling used select participants. This communities...

10.4102/sajhivmed.v19i1.721 article EN Southern African Journal of HIV Medicine 2018-08-09

Adolescent girls and young women aged 13-24 years are disproportionately affected by HIV in sub-Saharan Africa (1), resulting from biologic, behavioral, structural* factors, including violence. Girls also experience sexual violence at higher rates than do boys (2), who intimate partner have 1.3-2.0 times the odds of acquiring infection, compared with those not (3). Violence Against Children Youth Survey (VACS) data during 2007-2018 nine countries funded U.S. President's Emergency Plan for...

10.15585/mmwr.mm7047a2 article EN MMWR Morbidity and Mortality Weekly Report 2021-11-24

The emergence of antiretroviral therapy (ART) transformed HIV from a terminal illness to chronic disease. However, limited access health services remains one many barriers service utilisation by people living with (PLHIV) in low-resource settings. goal this study was describe the two provinces Zimbabwe.A qualitative descriptive conducted PLHIV and village workers (VHW) eight districts within provinces. Convenience sampling used select participants. This communities supported facilities more...

10.4102/hivmed.v19i1.721 article EN PubMed 2018-01-01

Background Zimbabwe adopted voluntary medical male circumcision (VMMC) as a priority HIV prevention strategy in 2007 and began implementation 2009. We evaluated the costs impact of this VMMC program to date future. Methods Three mathematical models describing Zimbabwe's epidemic evolution were calibrated household survey data on prevalence risk behaviors, with coverage program-reported VMMCs. compared trends new infections counterfactual without VMMC. Input assumptions agreed workshops...

10.1371/journal.pone.0199453 article EN cc-by PLoS ONE 2018-07-18

Abstract Introduction In sub‐Saharan Africa, less than half of young people know their HIV status. self‐testing (HIVST) is a testing strategy with the potential to offer privacy and autonomy. We aimed understand uptake acceptability different options for youth in Harare, Zimbabwe. Methods This study was nested within cluster randomized trial youth‐friendly community‐based integrated sexual reproductive health intervention aged 16–24 years. Three were offered: (1) provider‐delivered testing;...

10.1002/jia2.25815 article EN cc-by Journal of the International AIDS Society 2021-09-01

Objective Early HIV testing and diagnosis are paramount for increasing treatment initiation among children, necessary their survival improved health. However, uptake of pediatric is low in high-prevalence areas. We present data on attitudes towards from a nationally representative survey Zimbabwe. Methods All 18–24 year olds proportion 25–49 living randomly selected enumeration areas all ten Zimbabwe provinces were invited to self-complete an anonymous questionnaire personal digital...

10.1371/journal.pone.0053213 article EN cc-by PLoS ONE 2012-12-28

HIV testing is the entry point to access care. For HIV-infected children who survive infancy undiagnosed, diagnosis usually occurs on presentation health care services. We investigated effectiveness of routine opt-out (ROOT) compared with conventional opt-in provider-initiated and counseling (PITC) for attending primary clinics.After an evaluation PITC services aged 6-15 years in 6 facilities Harare, Zimbabwe, ROOT was introduced through a combination interventions. The change proportion...

10.1097/qai.0000000000000867 article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 2015-10-15

The World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) have set a Fast-Track goal to achieve 90% coverage of voluntary medical male circumcision (VMMC) among boys men aged 10-29 years in priority settings by 2021. We aimed identify age-specific facilitators VMMC uptake adolescents.

10.1093/cid/cix951 article EN cc-by Clinical Infectious Diseases 2018-01-12

Voluntary medical male circumcision (VMMC) is one of the first opportunities for adolescent males in African countries to interact with healthcare system. This study explored approaches used during VMMC counseling and whether these strategies maximize broader HIV prevention opportunities.Qualitative interviews were conducted 92 clients ages 10-19 years South Africa (n = 36), Tanzania Zimbabwe 20) 33 providers across three countries. Discussions counseling, testing, disclosure results. Audio...

10.1097/qad.0000000000001484 article EN AIDS 2017-06-29
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