Karina G. Pérez-Rubio

ORCID: 0000-0003-1767-1719
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About
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Research Areas
  • Natural Antidiabetic Agents Studies
  • Pharmacology and Obesity Treatment
  • Diet, Metabolism, and Disease
  • Diet and metabolism studies
  • Diabetes Treatment and Management
  • Berberine and alkaloids research
  • Pomegranate: compositions and health benefits
  • Phytochemistry and biological activities of Ficus species
  • Eicosanoids and Hypertension Pharmacology
  • Parkinson's Disease Mechanisms and Treatments
  • Diabetes Management and Research
  • Sirtuins and Resveratrol in Medicine
  • Advances in Cucurbitaceae Research
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • PARP inhibition in cancer therapy
  • Genomics and Rare Diseases
  • Vitamin C and Antioxidants Research
  • Sugarcane Cultivation and Processing
  • Synthesis and Biological Activity
  • Metabolism, Diabetes, and Cancer
  • Bee Products Chemical Analysis
  • Paraoxonase enzyme and polymorphisms
  • Cannabis and Cannabinoid Research
  • Pregnancy and Medication Impact

Universidad de Guadalajara
2014-2024

Secretaría de Salud de Jalisco
2021

Hospital de Especialidades
2015

Mexican Social Security Institute
2013

This study evaluated the effect of resveratrol administration on metabolic syndrome, insulin sensitivity, and secretion.A randomized, double-blind, placebo-controlled clinical trial was carried out in 24 patients with diagnosis syndrome accordance International Diabetes Federation criteria. Glucose levels were measured after a 75-gram dextrose load. Triglycerides high-density lipoprotein cholesterol concentrations at baseline also evaluated. Twelve received trans-resveratrol (500 mg) three...

10.1089/met.2014.0082 article EN Metabolic Syndrome and Related Disorders 2014-08-19

The aim of this study was to evaluate the effect berberine administration on metabolic syndrome, insulin sensitivity, and secretion.A randomized, double-blind, placebo-controlled clinical trial carried out in 24 patients with a diagnosis syndrome. Glucose levels after dextrose load were measured. Triglycerides high-density lipoprotein cholesterol concentrations at baseline also Twelve received hydrochloride (500 mg) three times daily before meals for 3 months. remaining 12 placebo. Area...

10.1089/met.2012.0183 article EN Metabolic Syndrome and Related Disorders 2013-06-28

An improvement in parameters of glycemic control has been observed with Momordica charantia patients type 2 diabetes mellitus (T2DM). It is unknown whether this through a modification insulin secretion, sensitivity, or both. We hypothesized that M. administration can improve secretion and/or sensitivity T2DM, without pharmacological treatment. The objective the study was to evaluate effect on and sensitivity. A randomized, double-blinded, placebo-controlled, clinical trial carried out 24 who...

10.1089/jmf.2017.0114 article EN Journal of Medicinal Food 2018-02-12

<i>Aim:</i> To evaluate the effect of pomegranate juice on insulin secretion and sensitivity in patients with obesity. <i>Methods:</i> A randomized, double-blind, placebo-controlled clinical trial was carried out 20 obese, adult volunteer subjects. After random allocation intervention, 10 received 120 ml or placebo while a fasted state for 1 month. Glucose, uric acid, creatinine, lipid profile, were measured at baseline, glucose also 30, 60, 90, min. The area under...

10.1159/000330116 article EN Annals of Nutrition and Metabolism 2011-01-01

Insulin resistance (IR) is a key molecular disorder related with diabetes mellitus, obesity, and cardiovascular disease. The objective of this study was to determine IR in adult primary care patients using the triglyceride/glucose (TyG) index [(Ln TG (mg/dL) × FG (mg/dL))/2].We conducted cross-sectional secondary analysis identified subjects according TyG index.There were 1500 included. Significant differences found between group versus insulin-sensitive group, respectively: age (in years),...

10.1097/jim.0000000000000130 article EN cc-by-nc-nd Journal of Investigative Medicine 2015-02-01

Background: The aim of this study was to evaluate the effect propolis or metformin versus placebo on glycemic control in pharmacological treatment-naïve patients with type 2 diabetes mellitus (T2DM). Methods: A double-blind, randomized, placebo-controlled parallel groups clinical trial performed 36 T2DM. They received (300 mg), (850 twice daily before breakfast and dinner for 12 weeks. At beginning end study, fasting plasma glucose (FPG), 2-h postload (2-h PG) during a 75-g oral tolerance...

10.1024/0300-9831/a000760 article EN International Journal for Vitamin and Nutrition Research 2022-08-15

The aim of this study was to evaluate the effect fucoxanthin on metabolic syndrome (MetS), insulin sensitivity, and secretion. A randomized, double-blind, placebo-controlled clinical trial conducted in 28 patients diagnosed with MetS. Patients were randomly assigned receive 12 mg or placebo once a day for weeks. Before after intervention, components MetS, sensitivity (Matsuda index), first phase secretion (Stumvoll total evaluated during 2-h oral glucose tolerance test. After administration,...

10.1089/jmf.2022.0103 article EN Journal of Medicinal Food 2023-07-01

Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors, usually with common pathophysiological origin in insulin resistance and abdominal obesity. Considering the reported effects ellagic acid (EA) on obesity, aim this study was to evaluate effect EA components MetS, sensitivity secretion by conducting randomized, double-blind, placebo-controlled, clinical trial 32 volunteers diagnosed MetS. Sixteen patients were randomly allocated, received 500 mg orally twice day for 12...

10.3390/jcm11195741 article EN Journal of Clinical Medicine 2022-09-28

The aim of this study was to evaluate the effect Momordica charantia (MC) administration on anthropometric measures in patients with obesity. A randomized, double-blind, placebo-controlled pilot clinical trial carried out 24 Twelve randomly received MC (2000 mg/day) for 12 weeks, and placebo. Body weight (BW), body mass index (BMI), waist circumference (WC), fat percentage, as well laboratory determinations, were evaluated before after intervention. Results showed that while reductions BW,...

10.1089/jmf.2021.0164 article EN Journal of Medicinal Food 2022-05-04

The aim of this study was to evaluate the effect Irvingia gabonensis on metabolic syndrome (MetS), insulin sensitivity, and secretion. A randomized, double-blind, placebo-controlled clinical trial performed in 24 patients with MetS accordance International Diabetes Federation criteria. Twelve received I. (150 mg) twice a day during 90 days, 12 placebo. Glucose concentrations were measured 2-h oral glucose tolerance test. Also, lipid profile, creatinine, uric acid, hepatic enzymes determined....

10.1089/jmf.2017.0092 article EN Journal of Medicinal Food 2018-01-16

To evaluate the effect of berberine (BBR) plus bezafibrate administration on lipid profile patients with mixed dyslipidemia. A double-blind randomized pilot clinical trial parallel groups was carried out in 36 patients, aged 30-60 years dyslipidemia [triglycerides (TG) ≥1.7 mM and total cholesterol (TC) ≥5.2 mM]. Patients were assigned to 3 12 each, receiving oral during 90 days BBR 500 mg t.i.d., 400 b.i.d., or t.i.d. b.i.d, respectively. Clinical evaluation, profile, glucose, creatinine,...

10.1089/jmf.2020.0029 article EN Journal of Medicinal Food 2020-05-13

Abstract INTRODUCTION We aimed to determine the effect of years schooling (YoS) and age on Mexican adaptation Consortium Establish a Registry for Alzheimer's Disease (CERAD‐MX) scores in preclinical carriers group (PCG) non‐carriers (NCG) APP V717I mutation. METHODS included 39 first‐degree relatives (PCG = 15; NCG 24). report eight CERAD‐MX tasks: Mini‐Mental State Examination (MMSE), Word List Learning (WLL), Delayed Recall (WLD) Recognition (WLR), Constructional Praxis Copy (CPC) (CPR),...

10.1002/dad2.12631 article EN cc-by-nc-nd Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2024-07-01

Currently, it is still unknown whether differences in glycemic control have any effect on glucose and insulin kinetics after vildagliptin administration. The aim of this study was to evaluate the concentrations during a 24-h period type 2 diabetes patients with different ranges baseline hemoglobin A1c (A1C) levels.A randomized, double-blind, crossover, placebo-controlled clinical trial carried out 12 drug-naive adult volunteers overweight or obesity. Subjects had fasting values between 7.2...

10.1089/dia.2013.0020 article EN Diabetes Technology & Therapeutics 2013-04-25

The Federation of European Nutrition Societies is a federation consisting 25 nutrition societies, each representing one country.The main FENS event the Conference, held every 4 years.According to statutes, has been established advance research and education in science nutrition.It will promote learning among nutritionists general, particular, by organizing meetings discussions, exchanging information other appropriate means.

10.1159/000331343 article EN Annals of Nutrition and Metabolism 2011-01-01

To evaluate the effect of Banaba (Lagerstroemia speciosa) on metabolic syndrome (MetS), insulin sensitivity, and secretion. A randomized, double-blind, placebo-controlled clinical trial was carried out in 24 patients with diagnosis MetS according to International Diabetes Federation criteria. Body weight, waist circumference, blood pressure were evaluated. Fasting plasma glucose (FPG) concentrations measured every 30 min during 2 h after a 75-g dextrose load. Lipid profile determined before...

10.1089/jmf.2021.0039 article EN Journal of Medicinal Food 2021-11-02

ResumenObjetivo: Evaluar la frecuencia de síndrome metabólico (SM), secreción insulina y resistencia a en adolescentes con sobrepeso obesidad.Métodos: Se llevó cabo un estudio transversal analítico 264 u obesidad.El SM se diagnosticó acorde los criterios Federación Internacional Diabetes.La evaluaron índices HOMA-IR HOMA-β, respectivamente.Un comité ética local aprobó el proyecto padres o tutores firmaron consentimiento informado.Las diferencias intergrupo fueron evaluadas Prueba t Student...

10.24875/alad.18000303 article ES cc-by-nc-nd Alad 2018-02-16
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