A5026694912- Geology and Paleoclimatology Research
- Archaeology and ancient environmental studies
- Geological and Geochemical Analysis
- Paleontology and Stratigraphy of Fossils
- Pacific and Southeast Asian Studies
- Thermochemical Biomass Conversion Processes
- Iron and Steelmaking Processes
- Hearing, Cochlea, Tinnitus, Genetics
- Granular flow and fluidized beds
- Isotope Analysis in Ecology
- Geological and Geophysical Studies
- Geomagnetism and Paleomagnetism Studies
- Pleistocene-Era Hominins and Archaeology
- Geological formations and processes
- Geochemistry and Geologic Mapping
- earthquake and tectonic studies
- Climate variability and models
- Methane Hydrates and Related Phenomena
- Cellular Mechanics and Interactions
- Cancer-related molecular mechanisms research
- Coal Combustion and Slurry Processing
- Coal Properties and Utilization
- Muscle Physiology and Disorders
- Geochemistry and Geochronology of Asian Mineral Deposits
- Tree-ring climate responses
Institute of Geology and Geophysics
2014-2025
Chinese Academy of Sciences
2014-2025
University of Chinese Academy of Sciences
2019-2024
Institute of Engineering Thermophysics
2023-2024
Zhejiang University
2011-2021
Blood Center of Zhejiang Province
2021
Sir Run Run Shaw Hospital
2021
Thermo Fisher Scientific (United States)
2021
China University of Petroleum, Beijing
2020
Center for Excellence in Tibetan Plateau Earth Sciences
2015-2017
Chemical analysis reveals early ritual cannabis smoking in the eastern Pamirs by 2500 years ago.
Abstract The genetic correction of induced pluripotent stem cells (iPSCs) from somatic patients with sensorineural hearing loss (caused by hereditary factors) is a promising method for its treatment. gene mutations in iPSCs could restore the normal function and provide rich source transplantation. In present study, were generated deaf patient compound heterozygous MYO7A (c.1184G>A c.4118C>T; P-iPSCs), asymptomatic father (MYO7A c.1184G>A mutation; CF-iPSCs), donor...
Abstract The Paleocene–Eocene Thermal Maximum (PETM; ∼56 Ma) was a period of extreme global warming associated with massive influx isotopically light carbon into the ocean–atmosphere system. burning Paleocene peatland (wildfire hypothesis) has been proposed as potential source. In addition, numerical models have predicted that wildfire activity would intensify in response to CO 2 ‐induced warming. this study, we tested hypothesis and model prediction by tracing history across PETM East Asia...
The early Eocene was marked by a series of rapid global warming events known as hyperthermals, offering insights into the planet’s biogeochemical responses to extreme climate conditions. While increased terrestrial methane (CH4) cycling has been recorded during Paleocene−Eocene thermal maximum (PETM; ca. 56 Ma), investigations CH4 cycle perturbations subsequent smaller-magnitude hyperthermals have lacking. Consequently, question whether all exhibited common feedback remains unanswered....
Abstract A series of transient global warming events between 56 and 50 Ma are characterized by a pronounced negative carbon isotope excursion (CIE). However, the documents these hyperthermals, such as Eocene Thermal Maximum 2 H2 events, have come chiefly from marine sediments, their expression in terrestrial organic is still poorly constrained. Here we yield high‐resolution record material Fushun Basin, which displays four prominent CIEs with magnitudes larger than 2.5‰. Based on age...
Fluid shear stress (FSS) is an important biomechanical factor regulating the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and therefore widely used in bone tissue engineering. However, mechanotransduction FSS hMSCs remains largely unknown. As β1 integrins are considered to be mechanoreceptors other cells, we suspect that should also for sense stimulation FSS. We a perfusion culture system produce loading on seeded PLGA three-dimensional (3D) scaffolds investigated roles...
Copolymer composite scaffolds and bioceramic/polymer are two representative forms of used for bone tissue engineering. Studies to compare biocompatibility bone-repairing effects between these significant selecting or improving the scaffold clinical application. We prepared porous comprising poly-lactic-acid/poly-glycolic-acid (PLGA) poly-lactic-acid/nano-hydroxyapatite (nHAP/PLA) respectively, examined their with human marrow-derived mesenchymal stem cells (hMSCs) through evaluating...
Better constraints on the uplift history of Tian Shan will increase our understanding both mountain building processes and deformation patterns related to India‐Asian collision. Anisotropy magnetic susceptibility (AMS) holds great potential track variations in tectonic strain, which is ultimately responsible for uplift. Here we present an AMS record, spanning interval 28–4 Ma, from fluviolucastrine Jingou River section foreland. Rock measurements show that are dominated by antiferromagnetic...
Abstract The mid‐Pliocene (~3.3–3.0 Ma) was the most recent warm interval during which atmospheric CO 2 concentrations were similar to present level of ~400 ppmv. Therefore, it is often regarded as an analog for a near‐future climate scenario. To examine behavior East Asian summer monsoon (EASM) period, northern edge EASM, sensitive indicator advance and retreat rainbelt, analyzed using output Pliocene Model Intercomparison Project Phase 1. results show ~150‐km‐northwestward migration EASM...
The current clinical treatments for complications caused by hepatobiliary surgery still have some inevitable weakness. aim of the study was to fabricate a tissue-engineered bile duct that utilized novel bilayered polymer scaffold combined with human bone marrow-derived mesenchymal stem cells (hMSCs) new treatment biliary disease. biocompatibility polycaprolactone (PCL) (PCL)/poly(lactide-co-glycolide) (PLGA) hMSCs first examined, and hMSC-PCL/PLGA constructs (MPPCs) prepared. MPPCs blank...
Abstract As the northernmost part of Indo‐Eurasian collision belt, Pamir‐Tian Shan convergence zone (PTCZ) is a strategic location for understanding intracontinental deformation. Here we present magnetostratigraphic investigation continuous section from Baxbulak region, to better constrain regional tectonic history. Rock magnetic analyses indicate that hematite and magnetite are main carriers characteristic remanent magnetization. The resulting polarity sequence allows distinct correlation...
Bone defects associated with soft tissue injuries are an important cause of deformity that threatens people's health and quality life. Although bone substitutes have been extensively explored, effective biomaterials can coordinate early inflammation regulation subsequent repair events still lacking. We prepared a spatial form periosteal extracellular matrix (ECM) scaffold, which has advantages in terms low immunogenicity, good retention bioactive ingredients, natural structure. The ECM...
Located on the Pamir Plateau in Xinjiang Province, China, Ji'erzankale Necropolis dates back to 2500 yr BP. Many materials that have been unearthed this cemetery, including shoo konghou (musical instrument), bronze mirrors and glass beads, suggest cultural transference between East West. Furthermore, small-sized rounded fire altars made from sweet-scented Sabina were found for first time regarded as implements veneration. We identified 70 wooden objects 25 tombs within Necropolis, each...
Abstract Deciphering the long‐term interaction among continental silicate weathering, global climate, and atmospheric CO 2 concentrations is helpful in understanding mechanisms of Cenozoic climate change accessing future climatic environmental response to anthropogenic carbon emissions. The Eocene, which characterized by Early Eocene Climatic Optimum (EECO) following cooling, represents an ideal test case. Here we generate geochemical data lacustrine sediments from Fushun Basin, northeast...
The ancient Loulan, situated on the west bank of Lake Lop Nur, Xinjiang, Northwest China, was an important town Silk Road connecting China to Europe. However, this once-prosperous kingdom has been a depopulated zone filled with wind-eroded mounds since approximately AD 500–600. A comprehensive understanding environmental setting flourishing Loulan civilization is prerequisite for assessing environment–human interaction there. Here, we present our survey, chronology, and archaeobotany (the...