A5071688010- Advanced biosensing and bioanalysis techniques
- Cerebrovascular and Carotid Artery Diseases
- Biosensors and Analytical Detection
- Hearing, Cochlea, Tinnitus, Genetics
- Lipid Membrane Structure and Behavior
- Neurological Disease Mechanisms and Treatments
- Photodynamic Therapy Research Studies
- Chronic Myeloid Leukemia Treatments
- Energy, Environment, Economic Growth
- Genetics and Neurodevelopmental Disorders
- Electrochemical sensors and biosensors
- Advanced Nanomaterials in Catalysis
- Spaceflight effects on biology
- Environmental Impact and Sustainability
- CRISPR and Genetic Engineering
- Phagocytosis and Immune Regulation
- Climate Change Policy and Economics
- Radiomics and Machine Learning in Medical Imaging
- Molecular Sensors and Ion Detection
- Sphingolipid Metabolism and Signaling
- Protein Interaction Studies and Fluorescence Analysis
- Endoplasmic Reticulum Stress and Disease
- Carbon and Quantum Dots Applications
- Pulmonary Hypertension Research and Treatments
- Hearing Loss and Rehabilitation
Hebei University
2023-2025
Fujian Normal University
2014-2025
Pingdingshan University
2022-2024
Zunyi Medical University
2012-2024
Far Eastern Memorial Hospital
2022
Fujian Jiangxia University
2022
Zhejiang University
2015-2021
Sun Yat-sen University
2019-2021
Shanghai Jiao Tong University
2014-2021
Lishui University
2021
Abstract Engineering wearable devices for in situ and on‐site monitoring of pesticide residues from plants a non‐destructive manner is great research value but remains huge challenge. In this study, plant‐wearable fluorescence sensor CdTe CDs@PVA@AG, designed constructed by embedding QDs polyvinyl alcohol (PVA) agarose (AG)‐co‐assembled double‐network hydrogel to transmit on‐the‐scene pesticides messages. Harnessing red emission stimuli‐responsive performance QDs, as well hydrogel's...
Abstract The genetic correction of induced pluripotent stem cells (iPSCs) from somatic patients with sensorineural hearing loss (caused by hereditary factors) is a promising method for its treatment. gene mutations in iPSCs could restore the normal function and provide rich source transplantation. In present study, were generated deaf patient compound heterozygous MYO7A (c.1184G>A c.4118C>T; P-iPSCs), asymptomatic father (MYO7A c.1184G>A mutation; CF-iPSCs), donor...
Biosensing applications require signal reporters to be sufficiently stable and biosafe as well highly efficient. Aggregation-induced emission (AIE) nanoparticles have proven capable of cell-imaging cancer therapy; however, realizing sensitive detection biomolecules remains a great challenge because their instability, biotoxicity, lack modifiable functional groups. Herein, we report self-assembling strategy fabricate AIE (PTDNPs) through the dispersion amphiphilic polymers (PTDs) in...
Bone formation is linked with osteogenic differentiation of mesenchymal stem cells (MSCs) in the bone marrow. Microgravity spaceflight known to reduce formation. In this study, we used a real microgravity environment SJ-10 Recoverable Scientific Satellite examine effects space on human marrow-derived (hMSCs). hMSCs were induced toward for 2 and 7 d cell culture device mounted satellite. The satellite returned Earth after going through experiments orbit 12 d, samples harvested analyzed...
Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in a major cause of deafness. Induced pluripotent stem (iPSCs) promising regenerating inner and treating hearing loss. Here, we investigated migration, differentiation, synaptic connections transplanted otic epithelial progenitors (OEPs) derived from human iPSCs mouse cochlea. Human urinary isolated healthy donor were reprogramed to form that induced differentiate into OEPs cell-like cells....
Photodynamic Therapy (PDT) represents a crucial strategy in cancer treatment, exploiting the unique properties of photosensitizers. Silicon phthalocyanine, second-generation photosensitizer, is known for its outstanding photophysical and biocompatibility, while betulinic acid recognized potent anticancer activity. In this study, was conjugated at axial position silicon phthalocyanine to synthesize Betulinic Acid-Axially Substituted Phthalocyanine (Bai-SiPc). The compound then encapsulated...
Silicon phthalocyanine complexes, characterized by two additional axial coordination sites, have gained significant attention as second-generation photosensitizers for Photodynamic Therapy (PDT). In this study, di-(5-methylthiazole-1- ethoxy) axially substituted (SZ-SiPc) was synthesized and further modified through methyl iodide treatment to produce di-(4-N-methyl-5-methylthiazole-1-ethoxy) diiodide (SZ-SiPc-I2). The cellular uptake, phototoxicity, dark toxicity of SZ-SiPc-I2 were evaluated...
Abstract Objectives Exposure to microgravity induces many adaptive and pathological changes in human bone marrow mesenchymal stem cells (hBMSCs). However, the underlying mechanisms of these are poorly understood. We revealed gene expression patterns hBMSCs under normal ground (NG) simulated (SMG), which showed an interpretation for by regulation signal pathways analysis. Materials methods In this study, were osteogenically induced 0, 2, 7 14 days gravity microgravity, followed analysis...
To investigate whether sphingosine-1-phosphate (S1P), an apoptosis-inhibitor would be able to inhibit chemotherapy induced human granulosa cell apoptosis. Cultures of primary cells were isolated from women undergoing in vitro fertilization (IVF). MTT assay was used measure the optimum concentration CTX and S1P acts on cells. Granulosa added with pertussis toxin (PTX), PI3K inhibitor LY294002. Western blot analysis analyze signaling pathway proteins We found that (10 mm) statistically...
Osteogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBMSCs) is regulated by various factors, including morphogenetic proteins (BMPs), Notch, growth hormones and mitogen-activated protein kinases (MAPKs). Tribbles homolog 3 (TRIB3), a pseudokinase, plays an important role cancer adipocytes. However, TRIB3 function osteogenic unknown, although it involved regulating signaling pathways associated with differentiation. Here, we found that was highly expressed during...
Objective: The purpose of the present study is to provide raw data for development guidelines tea production and management, as well relevant health standards. To investigate mycotoxin contamination in wet stored Pu-erh a market Guangzhou, we measured concentrations aflatoxin B1 (AFB1), fumonisin (FB1), deoxynivalenol (DON), T-2 toxin 70 samples.Methods: samples were randomly chosen market. Following crushing, brewing, filtration samples, contaminations FB1, DON, or assayed by ELISA...
Using field survey data gathered from seven villages in Youxi County southern China and a list of famous ancient trees groves, this study explored the cultural roots ecological interpretations village fengshui forests. The results show as follows: species selected by Chinese rural villagers bear symbolic meaning, including health, longevity, flourishing population, fortune, wealth. Fengshui belief, clan system, rules regulations, worship tradition, customs have all played important roles...
Objective To investigate the role of transforming growth factor-β1 (TGF-β1), Smad2/3 and Smad7 expressions in carotid artery remodeling renovascular hypertensive rats, also therapeutic effect Enalapril Amlodipine. Methods The rat (RHR) models with "two-kidney one-clip" were established, including model group (n = 6), sham-operated (10 mg/kg per day, n Amlodipine (5 6) combination (Amlodipine 2.5 day + 5mg/kg 6). medication continuous administrated for six weeks. Carotid morphological...