A5085358450- Advanced NMR Techniques and Applications
- Wastewater Treatment and Nitrogen Removal
- Advanced MRI Techniques and Applications
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Atomic and Subatomic Physics Research
- Atmospheric and Environmental Gas Dynamics
- interferon and immune responses
- Microtubule and mitosis dynamics
- Natural product bioactivities and synthesis
- Atmospheric chemistry and aerosols
- Phosphorus and nutrient management
- Membrane Separation Technologies
- Virus-based gene therapy research
- Air Quality Monitoring and Forecasting
- Influenza Virus Research Studies
- Solid-state spectroscopy and crystallography
- Environmental Quality and Pollution
- Protein Hydrolysis and Bioactive Peptides
- Long-Term Effects of COVID-19
- Digital Marketing and Social Media
- CO2 Sequestration and Geologic Interactions
- Enhanced Oil Recovery Techniques
- Constructed Wetlands for Wastewater Treatment
- Hydrocarbon exploration and reservoir analysis
Hebei University
2024-2025
Weatherford College
2024
University of California, Riverside
2023-2024
Nanjing Agricultural University
2023-2024
Central South University
2024
State Key Laboratory of Pollution Control and Resource Reuse
2021-2024
Tongji University
2021-2024
Nanjing Medical University
2023-2024
Third Xiangya Hospital
2024
Hohai University
2024
Abstract Engineering wearable devices for in situ and on‐site monitoring of pesticide residues from plants a non‐destructive manner is great research value but remains huge challenge. In this study, plant‐wearable fluorescence sensor CdTe CDs@PVA@AG, designed constructed by embedding QDs polyvinyl alcohol (PVA) agarose (AG)‐co‐assembled double‐network hydrogel to transmit on‐the‐scene pesticides messages. Harnessing red emission stimuli‐responsive performance QDs, as well hydrogel's...
λ-Carrageenan (Carr), a seaweed polysaccharide, is used as proinflammatory agent in research. Betulinic acid (BA), naturally occurring pentacyclic triterpenoid, exerts immunomodulatory, antioxidant, anti-inflammatory, antitumor, anti-malarial and anti-HIV effects. The aim of this study was to investigate whether BA anti-inflammatory effect against Carr-induced paw edema mice, how could mediate the expression inflammation-associated MAPK-COX-2-PGE2 signal pathway. pretreatment significantly...
Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-translational modification implicated in creation of an antiviral environment via immune response regulation. This brought them into focus as promising therapeutic targets, albeit close homology some human raised concerns regarding potential cross-reactivity and adverse effects for host. Here, we evaluate structure function macrodomain SARS-CoV-2, causative agent COVID-19. We show that it can antagonize...
α-dystroglycan is a highly O-glycosylated extracellular matrix receptor that required for anchoring of the basement membrane to cell surface and entry Old World arenaviruses into cells. Like-acetylglucosaminyltransferase (LARGE) key molecule binds N-terminal domain attaches ligand-binding moieties phosphorylated O-mannose on α-dystroglycan. Here we show LARGE modification laminin- virus-binding occurs specific Thr residues located at extreme N terminus mucin-like Deletion mutation analyses...
Edible lotus (Nelumbo nucifera G.) is widely consumed in Asian countries and treated as a functional food traditional medicinal herb due to its abundant bioactive compounds. Lotus rhizome peels, knots, seed embryos are important byproducts processing waste of edible with commercial significance. Nevertheless, the comprehensive phenolic profiling different parts still scarce. Thus, this study aimed review contents antioxidant potential seeds (embryo cotyledon) rhizomes (peel, knot, pulp)...
LARGE-dependent modification enables α-dystroglycan (α-DG) to bind its extracellular matrix ligands. Mutations in the LARGE gene and several others involved O-mannosyl glycan synthesis have been identified congenital limb-girdle muscular dystrophies that are characterized by perturbed glycosylation reduced ligand-binding affinity of α-DG. is a bifunctional glycosyltransferase alternately transfers xylose glucuronic acid, thereby generating heteropolysaccharides on α-DG confer ligand binding....
Abstract Influenza A viruses cause seasonal epidemics and global pandemics, representing a considerable burden to healthcare systems. Central the replication cycle of influenza is viral RNA-dependent RNA polymerase which transcribes replicates genome. The undergoes conformational rearrangements interacts with host proteins perform these functions. Here we determine structure 1918 virus in transcriptase replicase conformations using cryo-electron microscopy (cryo-EM). We then structurally...
Highlights•The protein composition of gamma-tubulin ring complexes (γ-TuRCs) varies in flies•Drosophila Mozart1 is non-essential, and its expression restricted to the testes•Mozart1 required for γ-TuRC recruitment specifically basal bodies•mzt1 mutants have defects body positioning sperm formationSummaryMicrotubules are essential various cell processes [1] nucleated by multi-protein γ-tubulin at microtubule organizing centers (MTOCs), including centrosomes [2–6]. Recruitment γ-TuRCs...
Purpose Acquisition timing and B 1 calibration are two key factors that affect the quality accuracy of hyperpolarized 13 C MRI. The goal this project was to develop a new approach using regional bolus tracking trigger Bloch‐Siegert mapping real‐time based on measurements, followed by dynamic imaging metabolites in vivo. Methods proposed implemented system which allows data processing control sequence. Real‐time center frequency upon arrival also added. feasibility applying framework for vivo...
Recent advancement in 2D image diffusion models has driven significant progress text-guided texture synthesis, enabling realistic, high-quality generation from arbitrary text prompts. However, current methods usually focus on synthesizing for single static 3D objects, and struggle to handle entire families of shapes, such as those produced by procedural programs. Applying existing naively each shape is too slow support exploring different parameter settings at interactive rates, also results...
Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes small (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however, this core non-essential in various species and absent from budding yeasts. Drosophila, Spindle defective-2 (Spd-2) Centrosomin (Cnn) redundantly recruit mitotic centrosomes. Here, we show that Spd-2 recruits γ-TuRCs formed via the core, but Cnn can γ-TuSCs directly its...
NF-κB is a critical transcription factor in the innate immune response to infection and shaping adaptive immunity. The identification of host virus proteins that modulate induction immunological memory important for improving virus-based vaccine design efficacy. In viruses, expression BTB-BACK Kelch-like (BBK) restricted poxviruses conserved within them, indicating importance these medically viruses. Using vaccinia (VACV), smallpox vaccine, we report VACV BBK protein A55 dysregulates...