A5069156212- Estrogen and related hormone effects
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Phytoestrogen effects and research
- Animal testing and alternatives
- Hydraulic Fracturing and Reservoir Analysis
- Advancements in Transdermal Drug Delivery
- Reservoir Engineering and Simulation Methods
- Immune cells in cancer
- CAR-T cell therapy research
- Neuroblastoma Research and Treatments
- Contact Dermatitis and Allergies
- Oil and Gas Production Techniques
- Reproductive System and Pregnancy
- Pharmaceutical studies and practices
- Menopause: Health Impacts and Treatments
- Pesticide Exposure and Toxicity
- Histone Deacetylase Inhibitors Research
- Medical History and Innovations
- Medical Imaging Techniques and Applications
- Vascular Malformations and Hemangiomas
- Neuroendocrine Tumor Research Advances
- Animal Genetics and Reproduction
- Nuclear Receptors and Signaling
- Vascular Tumors and Angiosarcomas
Google (United States)
2024
Princeton University
2023
Mpala Research Center and Wildlife Foundation
2023
The Ohio State University
2023
Nationwide Children's Hospital
2023
The London College
2023
Rensselaer Polytechnic Institute
2023
University of California, Irvine
2020
Endologix (United States)
2018
Peter MacCallum Cancer Centre
1999-2017
<h3>BACKGROUND AND PURPOSE:</h3> Convolutional neural networks are a powerful technology for image recognition. This study evaluates convolutional network optimized the detection and quantification of intraparenchymal, epidural/subdural, subarachnoid hemorrhages on noncontrast CT. <h3>MATERIALS METHODS:</h3> was performed in 2 phases. First, training cohort all NCCTs acquired at single institution between January 1, 2017, July 31, used to develop cross-validate custom hybrid 3D/2D mask...
Our work and that of others defined mitosis-specific (Rad21 subfamily) meiosis-specific (Rec8 proteins involved in sister chromatid cohesion several eukaryotes, including humans. Mutation the fission yeast Schizosaccharomyces pombe rec8 gene was previously shown to confer a number meiotic phenotypes, strong reduction recombination frequencies central region chromosome III, absence linear element polymerization, reduced pairing homologous chromosomes, cohesion, aberrant segregation, defects...
Increased intracellular cAMP and Ca2+ levels can activate transcription of a number eukaryotic genes through common promoter element, the cAMP/Ca2+ response element. This element is binding site for activating factor (ATF)/CREB proteins, an extensive family. Here we report that one member this family, ATF-1, mediate both transcriptional responses, but responses to two pathways differ in magnitude. In contrast, another family member, CREB, has been shown similar levels. Taken together, these...
To review the response and outcomes of (177)Lu-DOTA-octreotate chemoradionuclide therapy (LuTate PRCRT) in patients with neuroendocrine tumour (NET) expressing high levels somatostatin receptors uncontrolled symptoms or disease progression.A total 68 (39 men; 17 - 76 years age) who had completed an induction course at least three cycles LuTate PRCRT between January 2006 June 2010 were reviewed. Ten treated for 58 progression despite conventional treatment. The majority four (median treatment...
Recent reports of substantial urinary levels equol in pregnant macaques and humans pose a concern, because poisoning the ovine is characterized by an often permanent failure reproductive processes. Equol (Fig. 1), metabolite phytoestrogens, thought to act through estrogen receptors. The present study made direct comparison estrogenic activity from macaque urine, (±) 17β-estradiol (E2) vitro vivo. Relative binding affinity for rat uterine receptor was 1% that E2, dissociation rate very high....
1. The metabolic fate of levormeloxifene in the Sprague-Dawley rat, Cynomolgus monkey and postmenopausal volunteer has been investigated. 2. Two doses [14C]levormeloxifene, 0.7 50 mg/kg, were given to male female rat monkey, a single 20-mg dose volunteer. 3. primary route excretion all three species was faeces. Metabolism similar species, with demethylation forming major metabolite One metabolites involved an oxidative ring opening pyrrole ring. 4. main site metabolism is liver majority drug...
<title>Abstract</title> Novel types of digital data, including internet search have potential to improve understanding early predictors serious health conditions and enable timely management. While many studies used aggregate anonymized trends in this way, what is less clear the predictive or diagnostic value online searches at individual level. an increasing number these kinds research method still emerging. We therefore undertook a systematic review published that has assessed data....
We present a case of an otherwise healthy 20-month-old with congenital sensorineural hearing loss. CT and MR imaging demonstrated bilateral asymmetrically severe hypoplasia the internal auditory canals vestibulocochlear nerves. Additional developmental inner ear anomalies were in this patient, including unilateral semicircular canal suspected cochlear hypoplasia. The patient retained normal facial nerve function bilaterally. highlight current research understanding IAC abnormalities.
Abstract In regulating production on the United Kingdom Continental Shelf (UKCS) UK Department of Trade and Industry (DTI) has permitted operators, a case by basis, to produce below bubble point locally producer well in order accelerate or, where pressure support is not economically viable, more extensively. The maturity UKCS means that smaller fields are now being developed operators also looking reduce operating costs mature approaching cessation (COP). issue therefore becoming important....
Journal Article In vitro absorption of 1‐chloro 2,4‐dinitrobenzene (DNCB) through human, hooded rat and mouse epidermis R.C. SCOTT, SCOTT Central Toxicology Laboratory, Imperial Chemical Industries Plc, Alderley Park, Macclesfield, Cheshire SK10 4TJ, U.K. Search for other works by this author on: Oxford Academic Google Scholar M.A. THOMPSON, THOMPSON R.J. WARD, WARD J. RAMSEY, RAMSEY C. RHODES British Dermatology, Volume 115, Issue s31, 1 August 1986, Pages 47–48,...
2595 Background: MAK cell immunotherapy has demonstrated activity in Phase I/II trials for patients (pts) with relapsed ovarian cancer. However, little is known about the vivo distribution of these cells following injection. The aim this study was to track destination using PET or SPECT imaging after delivery via intravenous (i.v.) intraperitoneal (i.p.) injection pts recurrent epithelial Methods: were produced by vitro culture autologous monocytes, collected from apheresis. stimulated γ...
s for the 19th Annual Scientific Meeting of International Society Biological Therapy Cancer, San Francisco, California, November 4-7, 2004: Dendritic Cells and Vaccines