- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Clinical practice guidelines implementation
- Prostate Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Primary Care and Health Outcomes
- Patient Satisfaction in Healthcare
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diagnosis and Treatment of Venous Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Thermoregulation and physiological responses
- Peripheral Artery Disease Management
- Pressure Ulcer Prevention and Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Central Venous Catheters and Hemodialysis
- Neuroendocrine Tumor Research Advances
- Wound Healing and Treatments
- Health and Medical Research Impacts
- EEG and Brain-Computer Interfaces
- Thermal Regulation in Medicine
- Colorectal Cancer Surgical Treatments
Scarborough General Hospital
2022
Cardiff and Vale University Health Board
2012-2021
Cardiff University
2018-2021
University Hospitals Birmingham NHS Foundation Trust
2016
Papworth Hospital
2015
Great Western Hospital
2015
University Hospital of Wales
1995-2013
University of Wales
1987-1996
Hammersmith Hospital
1987-1989
Smith Institute
1987
The effect of an infusion two doses peptide YY (PYY), a novel putative gastrointestinal hormone, has been assessed on mouth to caecum intestinal transit time and the rate gastric emptying after ingestion inert 200 ml liquid meal thought unlikely interrupt fasting motility patterns. A low dose PYY was chosen give plasma concentrations within range seen postprandially in healthy subjects, while high mimicked raised levels several malabsorptive conditions. During at 0.18 pmol/kg/min rose from...
Objectives To assess the efficacy and safety of prostate artery embolization (PAE) for lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) conduct an indirect comparison PAE with transurethral resection (TURP). Patients Methods As a joint initiative between British Society Interventional Radiologists, Association Urological Surgeons National Institute Health Care Excellence, we conducted UK Register Prostate Embolization (UK‐ROPE) study, which recruited 305...
The effect on gut motility of a single subcutaneous injection 50 μg the long-acting somatostatin analogue, SMS 201–995, was investigated in 8 normal volunteers who took drink containing 99mTc and lactulose with mixed meal. rate gastric emptying assessed by disappearance isotope from stomach area as measured gamma camera, mouth-to-caecum transit time (MCTT) appearance hydrogen breath. Gastric accelerated, significant reduction taken to 50% (37.2 ± 3.3 min during control study vs 23.3 3.4...
Patients are experts in their own health and should be treated as equal partners care. Patient-reported outcome measures (PROMs) an effective way of gathering patient feedback can facilitate effectiveness cost-effectiveness analysis to improve decision making service improvement. The PROMs, PREMs & Effectiveness Programme was initiated 2016 aimed develop electronic platform collection PROMs experience (PREMs) from secondary care patients across Wales.
The patient-reported outcome measures (PROMs), experience measure (PREMs) and Effectiveness Programme (PPEP) launched with the aim of supporting all National Health Service Wales (NHS Wales) organisations to collect PROMs PREMs across a range conditions. is generic condition-specific electronically from every secondary care patient in provide that can be used determine clinical cost-effectiveness treatments services. This study reports on PPEP developing an electronic platform suitable for...
In current clinical practice, peripherally inserted central catheters (PICCs) are typically using external anatomical measurements and a confirmatory chest X-ray, or fluoroscopy. The Sherlock 3CG(®) Tip Confirmation System (TCS) allows magnetic tracking of the PICC tip during insertion confirmation final location ECG, meaning that most patients will not require X-ray TCS was evaluated in 2014 by UK National Institute for Health Care Excellence (NICE) as part Medical Technologies Evaluation...
Preliminary observations of rapid relief ischemic rest pain following appli cation a foot impulse compression device prompted this study to quantify its immediate effects. Blood flow was calculated by means duplex ultrasound imager interfaced with Doppler spectrum analyzer. Twelve normal subjects and 10 patients peripheral vascular disease (mean ankle/brachial systolic pressure index = 0.62 (range 0.33-0.74) were studied. Mean resting blood ( SD) not significantly different in the two...
In 2010 a retrospective audit was undertaken to assess the viability of using PROMs in patients with symptomatic cardiac arrhythmias having undergone percutaneous arrhythmia ablation. A response rate 74 % achieved, finding suggesting that reported significant impact on their work, social and family life.To conduct qualitative cross sectional survey understand patients' perspectives how affect daily lives, as part program develop Patient Reported Outcome Measure (PROM).Twenty five aged 18 or...
To assess the feasibility of administering Patient Reported Outcomes Measures (PROMs) in patients treated with ablation for cardiac arrhythmias, and to conduct first stage development testing a new PROM tool. A tool was developed by multidisciplinary team tested alongside an adaptation patient perception arrhythmia questionnaire (PPAQ) EQ-5D-5L multicentre retrospective audit involving 791 consecutive catheter at three UK centres over 13 months. Data were recorded National Cardiac Rhythm...
Patient experience teams in NHS Wales’ Health Boards and Trusts are working across the country to collect patient feedback from members of public who access health care services. Although this work is advanced many areas, there currently no way benchmarking organisations, reducing opportunities for shared learning. We aimed with patients colleagues Wales agree a set universal Reported Experience Measures (PREMs) questions. Working teams, groups Welsh Government, Outcome (PROMs),...
A standardised terminology for describing medical devices can enable safe and unambiguous exchange of information. Proposed changes to EU-wide regulations mandate the use such a system. This article reviews two important classification systems in UK. The Global Medical Device Nomenclature (GMDN) provides system specifically diagnostics, facilitates data between manufacturers regulators. SNOMED CT is choice NHS communicating, sharing storing information about patients’ healthcare episodes....
Abstract ‘Hard‐to‐heal’ wounds are those which fail to heal with standard therapy in an orderly and timely manner may warrant the use of advanced treatments such as non‐contact low‐frequency ultrasound ( NLFU ) therapy. This evaluator‐blinded, single‐site, randomised controlled trial, compared addition UK care [ SOC : + )] three times a week, alone at least once week. Patients chronic venous leg ulcers were eligible participate. All 36 patients completed treatment (17 , 19 ), baseline...
To formally test and validate a patient-reported outcome measure (PROM) for patients with cardiac arrhythmias undergoing catheter ablation procedures in the UK [Cardiff Cardiac Ablation PROM (C-CAP)]. A multicentre, prospective, observational cohort study consecutive patient enrolment from three sites was conducted. Patients were sent C-CAP questionnaires before after an procedure. Pre-ablation C-CAP1 (17 items) comprised four domains: expectations; condition symptoms; restricted activity...
Abstract Aims To investigate long‐term efficacy of cardiac ablation for symptomatic arrhythmia by gathering generic and arrhythmia‐related quality life data using patient‐reported outcome measures before after ablation. Methods Consecutive patients undergoing procedures at three sites in the United Kingdom were enrolled (n = 561). Data collected baseline, 8–16 weeks, 12 months with responses from 390 received all time points. Nonparametric tests used to identify any changes patient outcomes...