A5066968032- Ferroptosis and cancer prognosis
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related gene regulation
- RNA modifications and cancer
- Extracellular vesicles in disease
- RNA Research and Splicing
Air Force Medical University
2023-2025
University of South China
2023
Xiangya Hospital Central South University
2023
Central South University
2023
Xijing Hospital
2023
Metal regulatory transcription factor 1 (MTF1) has been reported to be correlated with several human diseases, especially like cancers. Exploring the underlying mechanisms and biological functions of MTF1 could provide novel strategies for clinical diagnosis therapy In this study, we conducted comprehensive analysis evaluate profiles in pan-cancer. For example, TIMER2.0, TNMplot GEPIA2.0 were employed analyze expression values The methylation levels evaluated via UALCAN DiseaseMeth version...
Abstract Background As a new type of regulatory cell death, ferroptosis has been proven to be involved in cancer pathogenesis and therapeutic response. However, the detailed roles or ferroptosis‐associated genes glioma remain clarified. Methods Here, we performed TMT/iTRAQ‐Based Quantitative Proteomic Approach identify differentially expressed proteins between specimens adjacent tissues. Kaplan–Meier survival was used estimate values. We also explored abnormally formin homology 2...
Ferroptosis is a cell death form that has been reported to be involved in the progression of gastric cancer (GC). However, underlying mechanism ferroptosis GC still needs further explored. This study conducted survey regarding biological functions ferroptosis-related gene AKR1C2 GC. Multiple bioinformatic platforms were applied indicate expression level was downregulated tissues, which displayed good prognostic value. Clinical statistics proved correlated with several tumor characteristics...
Glioma is the most common tumor of nervous system. The diffuse growth and proliferation glioma poses great challenges for its treatment. Here, Transcriptomic analysis revealed that Rac GTPase activating protein 1 (RACGAP1) highly expressed in glioma. RACGAP1 has been shown to play an important role malignant biological progression a variety tumors. However, underlying mechanism remain poorly understood. By using quantitative real-time polymerase chain reaction (qRT-PCR), western blot,...