Luc Belzunces

ORCID: 0000-0003-1798-9962
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About
Contact & Profiles
Research Areas
  • Insect and Pesticide Research
  • Insect and Arachnid Ecology and Behavior
  • Plant and animal studies
  • Bee Products Chemical Analysis
  • Pesticide Exposure and Toxicity
  • Cholinesterase and Neurodegenerative Diseases
  • Effects and risks of endocrine disrupting chemicals
  • Pesticide Residue Analysis and Safety
  • Insect Pest Control Strategies
  • Agriculture and Rural Development Research
  • Environmental Toxicology and Ecotoxicology
  • Neurobiology and Insect Physiology Research
  • Animal Ecology and Behavior Studies
  • Horticultural and Viticultural Research
  • Toxic Organic Pollutants Impact
  • Invertebrate Taxonomy and Ecology
  • Insect-Plant Interactions and Control
  • Rabbits: Nutrition, Reproduction, Health
  • Agricultural safety and regulations
  • Carcinogens and Genotoxicity Assessment
  • Pesticide and Herbicide Environmental Studies
  • Plant Physiology and Cultivation Studies
  • Medical Device Sterilization and Disinfection
  • Cephalopods and Marine Biology
  • Chemistry and Chemical Engineering

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
1992-2024

Association pour l'Utilisation du Rein Artificiel dans la région Lyonnaise
2013-2024

Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2024

Département Environnement et Agronomie
2001-2022

Écologie des Forêts Méditerranéennes
2021

Institut National de la Recherche Agronomique
1992-2015

AgroParisTech
2007-2013

Université d'Avignon et des Pays de Vaucluse
2000-2007

Groupe de Recherche en Agriculture Biologique
1997-1998

Institut National de la Recherche Agronomique du Niger
1997

Honey bee colonies are highly dependent upon the availability of floral resources from which they get nutrients (notably pollen) necessary to their development and survival. However, foraging areas currently affected by intensification agriculture landscape alteration. Bees therefore confronted disparities in time space resource abundance, type diversity, might provide inadequate nutrition endanger colonies. The beneficial influence pollen on health is well-established but whether quality...

10.1371/journal.pone.0072016 article EN cc-by PLoS ONE 2013-08-05

Summary Global pollinators, like honeybees, are declining in abundance and diversity, which can adversely affect natural ecosystems agriculture. Therefore, we tested the current hypotheses describing honeybee losses as a multifactorial syndrome, by investigating integrative effects of an infectious organism insecticide on health. We demonstrated that interaction between microsporidia Nosema neonicotinoid (imidacloprid) significantly weakened honeybees. In short term, combination both agents...

10.1111/j.1462-2920.2009.02123.x article EN Environmental Microbiology 2009-12-28

In less than 20 years, neonicotinoids have become the most widely used class of insecticides with a global market share more 25%. For pollinators, this has transformed agrochemical landscape. These chemicals mimic acetylcholine neurotransmitter and are highly neurotoxic to insects. Their systemic mode action inside plants means phloemic xylemic transport that results in translocation pollen nectar. wide application, persistence soil water potential for uptake by succeeding crops wild make...

10.1016/j.cosust.2013.05.007 article EN cc-by-nc-nd Current Opinion in Environmental Sustainability 2013-06-06

Background The honeybee, Apis mellifera, is undergoing a worldwide decline whose origin still in debate. Studies performed for twenty years suggest that this may involve both infectious diseases and exposure to pesticides. Joint action of pathogens chemicals are known threaten several organisms but the combined effects these stressors were poorly investigated honeybees. Our study was designed explore effect Nosema ceranae infection on honeybee sensitivity sublethal doses insecticides...

10.1371/journal.pone.0021550 article EN cc-by PLoS ONE 2011-06-28

Imidacloprid is a systemic nitroguanidine insecticide that belongs to the neonicotinoid family. As an agonist of acetylcholine receptor, it attacks insect nervous system and extremely effective against various sucking mining pests. Oral acute chronic toxicity imidacloprid its main metabolites (5-hydroxyimidacloprid, 4,5-dihydroxyimidacloprid, desnitroimidacloprid, 6-chloronicotinic acid, olefin, urea derivative) were investigated in Apis mellifera. Acute intoxication by or resulted rapid...

10.1897/1551-5028(2001)020<2482:dbaact>2.0.co;2 article EN Environmental Toxicology and Chemistry 2001-01-01

The microsporidium Nosema ceranae is a newly prevalent parasite of the European honey bee (Apis mellifera). Although this presently spreading across world into its novel host, mechanisms by it which affects bees and how respond are not well understood. We therefore performed an extensive characterization effects at molecular level using genetic biochemical tools. transcriptome modifications midgut were characterized seven days post-infection with tiling microarrays. Then we tested response...

10.1371/journal.pone.0037017 article EN cc-by PLoS ONE 2012-05-18

Intensive agricultural systems often expose honey bees (Apis mellifera L.) to large temporal variations in the availability (quantity, quality and diversity) of nutritional resources. Such irregularity is expected affect bee health. We therefore tested under laboratory conditions effect such variation pollen on health (survival nursing physiology-hypopharyngeal gland development vitellogenin expression). fed with different diets composed pellets collected by an landscape western France....

10.1371/journal.pone.0162818 article EN cc-by PLoS ONE 2016-09-15

Abstract Imidaclopridi a systemic nitroguanidine insecticide that belongs to theneonicotinoid family. As an agonist of the acetylcholine receptor, it attacks insect nervous system and is extremely effective against various sucking mining pests. Oral acute chronic toxicity imidacloprid its main metabolites (5‐hydroxyimidacloprid, 4,5‐dihydroxyimidacloprid, desnitroimidacloprid, 6‐chloronicotinic acid, olefin, urea derivative) were investigated in Apis mellifera . Acute intoxication by or...

10.1002/etc.5620201113 article EN Environmental Toxicology and Chemistry 2001-11-01

In ecosystems, a variety of biological, chemical and physical stressors may act in combination to induce illness populations living organisms. While recent surveys reported that parasite-insecticide interactions can synergistically negatively affect honeybee survival, the importance sequence exposure has hardly received any attention. this work, Western honeybees (Apis mellifera) were sequentially or simultaneously infected by microsporidian parasite Nosema ceranae chronically exposed...

10.1038/srep00326 article EN cc-by-nc-sa Scientific Reports 2012-03-22

Abstract Imidacloprid (1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine) belongs to a new chemical family of chloronicotinyl compounds whose mode action on the insect nervous system differs from that traditional neurotoxic products. Imidacloprid, strong systemic compound, is effective against several sucking and mining pests. The acute toxicity contact oral applications two Apis mellifera subspecies, caucasica, was investigated. In all toxicological studies, each dose included...

10.1002/etc.5620190726 article EN Environmental Toxicology and Chemistry 2000-07-01

SummaryModern agriculture often involves the use of pesticides to protect crops. These substances are harmful target organisms (pests and pathogens). Nevertheless, they can also damage non-target animals, such as pollinators entomophagous arthropods. It is obvious that undesirable side effects on environment should be reduced a minimum. Western honey bees (Apis mellifera) very important from an agricultural perspective vulnerable pesticide-induced impacts. They contribute actively...

10.3896/ibra.1.52.4.14 article ES Journal of Apicultural Research 2013-01-01

The present study was intended to evaluate the responses of enzymes in honeybee Apis mellifera after exposure deltamethrin, fipronil, and spinosad their use as biomarkers. After determination median lethal doses (LD50), honeybees were exposed at 5.07 ng/bee 2.53 for 0.58 0.29 4.71 2.36 (equivalent 1/10th [LD50/10] 1/20th [LD50/20] LD50, respectively). acetylcholinesterase (AChE), carboxylesterases (CaEs-1-3), glutathione-S-transferase (GST), catalase (CAT), alkaline phosphatase (ALP)...

10.1002/etc.2288 article EN Environmental Toxicology and Chemistry 2013-05-24

The gut of the European honeybee Apis mellifera is site exposure to multiple stressors, such as pathogens and ingested chemicals. Therefore, microbiota, which contributes host homeostasis, may be altered by these stressors. abundance major bacterial taxa in was evaluated response infection with intestinal parasite Nosema ceranae or chronic low doses neurotoxic insecticides coumaphos, fipronil, thiamethoxam, imidacloprid. Experiments were performed under laboratory conditions on adult workers...

10.1264/jsme2.me18169 article EN Microbes and Environments 2019-01-01

Abstract Recent studies highlighted that exposure to glyphosate can affect specific members of the core gut microbiota honey bee workers. However, in this study, bees were exposed relatively high concentrations. Here, we chronically newly emerged imidacloprid, and difenoconazole, individually a ternary mixture, at an environmental concentration 0.1 µg/L. We studied effects these exposures on establishment microbiota, physiological status, longevity, food consumption host. The bacterial...

10.1038/s41598-022-08009-2 article EN cc-by Scientific Reports 2022-03-11

Abstract Biotransformation of imidacloprid and the appearance olefin 5‐hydroxyimidacloprid metabolites in honeybee were studied by HPLC‐MS/MS analysis. Honeybees treated orally with at 20 50 µg kg −1 bee. Imidacloprid was metabolised relatively quickly thoroughly. Twenty minutes after beginning ingestion, sum residues from three compounds amounted to only 70% actual given dose. Imidacloprid, represented, respectively, 50%, 9% 8% ingested Six 24 h, ingestion bee, could no longer be detected...

10.1002/ps.772 article EN Pest Management Science 2003-11-03
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