- Developmental Biology and Gene Regulation
- Congenital heart defects research
- Craniofacial Disorders and Treatments
- Congenital gastrointestinal and neural anomalies
- Cleft Lip and Palate Research
- Animal Genetics and Reproduction
- Hemispheric Asymmetry in Neuroscience
- Hedgehog Signaling Pathway Studies
- Congenital Ear and Nasal Anomalies
- Paleontology and Evolutionary Biology
- Neurogenesis and neuroplasticity mechanisms
- Angiogenesis and VEGF in Cancer
- Axon Guidance and Neuronal Signaling
- dental development and anomalies
- Ichthyology and Marine Biology
- Reproductive Physiology in Livestock
- Muscle Physiology and Disorders
- Cell Adhesion Molecules Research
- Comparative Animal Anatomy Studies
- Epigenetics and DNA Methylation
- Fish Ecology and Management Studies
- Medical and Biological Sciences
- Hypothalamic control of reproductive hormones
- Ocular Disorders and Treatments
- Dupuytren's Contracture and Treatments
Cornell University
2005-2018
New York State College of Veterinary Medicine
1988-2013
Institute of Biomedical Science
2012
Vanderbilt University
1992
Ithaca College
1989
University of Massachusetts Boston
1980
University of Massachusetts Amherst
1978-1979
Washington University in St. Louis
1975
Abstract The method of embryonic tissue transplantation was used to confirm the dual origin avian cranial sensory ganglia, map precise locations anlagen these neurons, and identify placodal neural crest‐derived neurons within ganglia. Segments crest or strips presumptive ectoderm were excised from chick embryos replaced with homologous tissues quail embryos, whose cells contain a heterochromatin marker. Placode‐derived associated nerves V, VII, IX, X are located distal neurons. generally...
The objective of these experiments was to determine the embryonic origins craniofacial and cervical voluntary muscles associated connective tissues in chick. To accomplish this, suspected primordia, including somitomeres 3-7, somites 1-7, cephalic neural crest primordia have been transplanted from quail into chick embryos. Quail cells can be detected by presence a species-specific nuclear marker. results are summarized as follows: (table; see text) These indicate that with branchial arch...
ABSTRACT We have isolated two mouse genes, Mox-1 and Mox-2 that, by sequence, genomic structure expression pattern, define a novel homeobox gene family probably involved in mesodermal regionalization somitic differentiation. is genetically linked to the keratin Hox-2 genes of chromosome 11, while maps 12. At primitive streak stages (approximately 7.0 days post coitum), expressed mesoderm lying posterior future primordial head heart. It not neural tissue, ectoderm, or endoderm. may therefore...
Abstract Fate maps based on quail–chick grafting of avian cephalic neural crest precursors and paraxial mesoderm cells have identified the majority derivatives from each population but not unequivocally resolved precise locations dynamics at interface between them. The relation these two mesenchymal tissues is especially critical for development skeletal muscles, because play an essential role in their differentiation subsequent spatial organization. It known whether myogenic skeletogenic...
Myogenic populations of the avian head arise within both epithelial (somitic) and mesenchymal (unsegmented) mesodermal populations. The former, which gives rise to neck, tongue, laryngeal, diaphragmatic muscles, show many similarities trunk axial, body wall, appendicular muscles. However, muscle progenitors originating unsegmented mesoderm exhibit several distinct features, including multiple ancestries, absence somite lineage-determining regulatory gene products, diverse locations relative...
Neurogenic placodes are focal ectodermal thickenings that give rise to the sensory neurons, and in some cases, receptor cells of vertebrate systems. There no markers for identification undifferentiated placodal epithelia, but derivatives nasal placode, example, characterized by unique production GnRH olfactory marker protein. Placode morphogenesis occurs invagination and/or delamination form neuroblasts migratory primordia (e g, lateral line receptors). Specification neurogenic pattern...