- Abdominal Surgery and Complications
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Anesthesia and Neurotoxicity Research
- Hemodynamic Monitoring and Therapy
- Minimally Invasive Surgical Techniques
Radboud University Nijmegen
2020-2024
Radboud University Medical Center
2020-2024
Canisius-Wilhelmina Ziekenhuis
2024
To compare the effectiveness of low intra-abdominal pressure (IAP) facilitated by deep neuromuscular block (NMB) to standard practice in improving quality recovery, preserving immune function, and enhancing parietal perfusion during robot-assisted radical prostatectomy (RARP).
Abstract Background Muscle relaxants are routinely used during anesthesia to facilitate endotracheal intubation and optimize surgical conditions. However, controversy remains about the required depth of neuromuscular block (NMB) needed for optimal working conditions how this relates other outcomes. For instance, a deep yields superior compared standard NMB in laparoscopic surgery, however, robust association (safety) outcomes has not yet been established. Methods Trial design: an...
Background The number of trials investigating the effects deep neuromuscular blockade (NMB) on surgical conditions and patient outcomes is steadily increasing. Consensus which procedures benefit from NMB (a posttetanic count [PTC] 1 to 2) how implement it has not been reached. European Society Anaesthesiology Intensive Care does advise routine application but recommends use improve indication. This study investigates optimal dosing strategy reach maintain adequate during total intravenous...
Abstract Study objective To assess whether different intensities of intra-abdominal pressure and deep neuromuscular blockade influence the risk intra-operative surgical complications during laparoscopic donor nephrectomy. Design A pooled analysis ten previously performed prospective randomized controlled trials. Setting Laparoscopic nephrectomy in four academic hospitals Netherlands: Radboudumc, Leiden UMC, Erasmus MC Rotterdam, Amsterdam UMC. Patients Five hundred fifty-six patients...