A5020777539- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Anesthesia and Neurotoxicity Research
- COVID-19 Clinical Research Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Abdominal Surgery and Complications
- Intraoperative Neuromonitoring and Anesthetic Effects
- Energy and Environment Impacts
- COVID-19 and Mental Health
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Blood Coagulation and Thrombosis Mechanisms
- Minimally Invasive Surgical Techniques
- Energy, Environment, and Transportation Policies
- Diamond and Carbon-based Materials Research
- Carbon Nanotubes in Composites
- Semiconductor materials and devices
- Hernia repair and management
- S100 Proteins and Annexins
- Heparin-Induced Thrombocytopenia and Thrombosis
- Neuropeptides and Animal Physiology
- Platelet Disorders and Treatments
Radboud University Nijmegen
2021-2025
Radboud University Medical Center
2021-2025
University Medical Center
2024
KU Leuven
2011
Increasing evidence shows that postoperative innate immune dysregulation is associated with delayed recovery and infectious complications. The aim of this study was to compare the effects general versus spinal anesthesia on function during after total hip arthroplasty (THA). This comparative matched cohort used data from two single-center randomized-controlled trials. Patients control group HIPPO received were patients MAGIC who in a 2:1 ratio (general(n = 18); spinal(n 9)). Immune assessed...
Postoperative immunosuppression is a well known phenomenon associated with infectious complications. Peri-operative immune dysregulation likely induced by surgical damage and anaesthetics, but remains far from comprehensively characterised. To address this, the effects of individual drugs on function must be explored. Sugammadex, cyclodextrin that encapsulates rocuronium, also binds other structures may influence inflammatory response. Investigate potential immunomodulatory effect...
Comprehensive studies investigating sustained hypercoagulability, endothelial function, and/or inflammation in relation to post-COVID-19 (PCC) symptoms with a prolonged follow-up are currently lacking. Therefore, the aim of this single-centre cohort study was investigate serum biomarkers coagulation activation, microvascular dysfunction, and persisting two years after acute COVID-19.Patients diagnosed SARS-CoV-2 infection between February June 2020 were recruited. Outcome measures included...
Abstract Background Breast cancer is the second most common cause of death from in women worldwide. Counterintuitively, large population-based retrospective trials report better survival after breast-conserving surgery (BCS) compared to mastectomy, corrected for tumour- and patient variables. More extensive surgical tissue injury activation sympathetic nervous system by nociceptive stimuli are associated with immune suppression. We hypothesized that mastectomy causes a higher expression...
Introduction: Among its effect on virtually all other organs, COVID-19 affects the cardiovascular system, potentially jeopardizing health of millions. Previous research has shown no indication macrovascular dysfunction as reflected by carotid artery reactivity, but sustained microvascular dysfunction, systemic inflammation, and coagulation activation at 3 months after acute COVID-19. The long-term effects vascular function remain unknown. Materials Methods: This cohort study involved 167...
To compare the effectiveness of low intra-abdominal pressure (IAP) facilitated by deep neuromuscular block (NMB) to standard practice in improving quality recovery, preserving immune function, and enhancing parietal perfusion during robot-assisted radical prostatectomy (RARP).
There is accumulating evidence that deep neuromuscular blockade (NMB) improves intraoperative surgical conditions during laparoscopic surgery. Studies investigating the effects of NMB in open surgery are scarce. In theory, by limiting damage through deeper muscle relaxation, postoperative inflammation and concomitant immune suppression can be reduced. Therefore, this study will investigate total hip arthroplasty, which demands a relatively large exposure joint between muscles.This monocentre...
Background and Aims: Epidemiologic studies indirectly suggest that air pollution accelerates atherosclerosis. We hypothesized individual exposure to particulate matter (PM) derived from fossil fuel would correlate with plasma concentrations of oxidized low-density lipoprotein (LDL), taken as a marker tested this hypothesis in susceptible population patients diabetes. Methods: In cross-sectional study non-smoking adult outpatients diabetes we assessed chronic PM by measuring the area occupied...
We have recently reported that an emission site density of 2/spl times/10/sup 5//cm/sup 2/ and a current 100 mA/cm/sup can be achieved routinely over relatively large area at extraction field about 10 V//spl mu/m for our carbon thin films. Films with such properties are already good enough to used low medium resolution displays. To make any usable device, however, the cathode has addressable. One problems proved particularly challenging in pursuing addressable is overcome edge from feed...