A5043946270- Methane Hydrates and Related Phenomena
- Earthquake Detection and Analysis
- Geophysics and Gravity Measurements
- Nicotinic Acetylcholine Receptors Study
- Ion channel regulation and function
- Seismic Waves and Analysis
- Ionosphere and magnetosphere dynamics
- Bacterial Genetics and Biotechnology
- Porphyrin Metabolism and Disorders
- Astrophysics and Cosmic Phenomena
- Glutathione Transferases and Polymorphisms
- Genomics, phytochemicals, and oxidative stress
- Hemoglobin structure and function
- Clostridium difficile and Clostridium perfringens research
- Poxvirus research and outbreaks
- Electron and X-Ray Spectroscopy Techniques
- Supercapacitor Materials and Fabrication
- Advanced Sensor and Energy Harvesting Materials
- Advanced Electron Microscopy Techniques and Applications
- Selenium in Biological Systems
- Insect and Pesticide Research
- Physics of Superconductivity and Magnetism
- Amphibian and Reptile Biology
- Conducting polymers and applications
- Photosynthetic Processes and Mechanisms
The University of Texas Southwestern Medical Center
2019-2025
Jahangirnagar University
2022-2024
Bangladesh University of Textiles
2024
Southwestern Medical Center
2019-2022
SPring-8
2017-2022
University of Hyogo
2017-2022
Gazipur Agricultural University
2015
Recent advances in wearable electronics have been propelled by the rapid growth of microelectronics and Internet Things. The proliferation electronic devices sensors relies heavily on power sources, predominantly batteries, with significant implications for environment. To address this concern to reduce carbon emissions, there is a growing emphasis renewable energy harvesting technologies, among which textile‐based triboelectric nanogenerators (T‐TENGs) stand out as an innovative sustainable...
Bacterial pathogens acquire heme from the host hemoglobin as an iron nutrient for their virulence and proliferation in blood. Concurrently, they encounter cytotoxic-free that escapes heme-acquisition process. To overcome this toxicity, many gram-positive bacteria employ ATP-binding cassette heme-dedicated efflux pump, HrtBA cytoplasmic membranes. Although genetic analyses have suggested expels bacterial membranes, molecular mechanism of remains elusive due to lack protein studies. Here, we...
CryoEM increasingly attempts to incorporate time-resolved techniques bridge the gap between static images and dynamic processes. Here we describe simple LED-based photo-flash system designed simplify sample preparation for cryogenic electron microscopy (cryoTREM). This user-friendly offers flexibility in its operation, is cost-effective, achieves uniform light exposure with minimal heat impact on samples before plunge freezing. We mechanical, electronic optical components, that are tailored...
The neuronal α7 nicotinic acetylcholine receptor (α7-nAChR) and muscle-type (mt-nAChR) are pivotal in synaptic signaling within the brain neuromuscular junction respectively. Additionally, they both targets of a wide range drugs toxins. Here, we utilize cryoEM to delineate structures these nAChRs complex with conotoxins ImI ImII from Conus imperialis. Despite nominal sequence divergence, exhibit discrete binding preferences adopt drastically different conformational states upon binding....
Abstract General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels inhibiting excitatory channels, with the net effect of dampening nervous system excitability. Neuromuscular antagonizing nicotinic acetylcholine receptors at motor endplate; these ligand-gated also inhibited general anesthetics. The mechanisms which inhibit poorly understood but underlie safe...
As the resolution revolution in CryoEM expands to encompass all manner of macromolecular complexes, an important new frontier is implementation cryogenic time resolved EM (cryoTREM). Biological complexes are dynamic systems that undergo conformational changes on timescales from microseconds minutes. Understanding nature biological critical understanding function. To realize full potential CryoEM, methods will be integral coupling static structures functions. Here, we present LED-based...
Periplasmic heme-binding proteins (PBPs) in Gram-negative bacteria are components of the heme acquisition system. These shuttle across periplasmic space from outer membrane receptors to ATP-binding cassette (ABC) importers located inner-membrane. In present study, we characterized structures PBPs found pathogen Burkholderia cenocepacia (BhuT) and thermophile Roseiflexus sp. RS-1 (RhuT) heme-free heme-bound forms. The conserved motif, which a well-conserved Tyr interacts with nearby Arg...
Glutathione S-transferease (GST) activities involved in antioxidant defense and methylglyoxal detoxification were investigated the seedlings of a Bangladeshi maize variety, BARI hybrid maize-7, to understand protecting mechanism under cold stress condition. The glutathione S-transferase increased, while catalase (CAT) decreased with duration stress. western blot analysis dominant GST revealed that it significantly accumulated during period. continual increase H2O2 contents along reduced...
Glutathione S-transferases (GSTs, EC: 2.5.1.18) and Glyoxalases [Glyoxalase-I (Gly-I, 4.4.1.5) glyoxalase-II (Gly-II, 3.1.2.6)] are major glutathione dependent detoxification as well important antioxidants enzymes in plants. On the other hand, proline betaine osmoprotectants plants under abiotic stresses including salinity. In this study, roles of GST, Gly-I, Gly-II were investigated on cytotoxic metabolites presence 15 mM 16 dSm-1 salinity leaves seedlings a saline tolerant maize inbred...