Mahmut Koparal

ORCID: 0000-0003-1817-1230
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About
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Research Areas
  • Oral and Maxillofacial Pathology
  • Temporomandibular Joint Disorders
  • Bone Tumor Diagnosis and Treatments
  • Dental Radiography and Imaging
  • Dental Anxiety and Anesthesia Techniques
  • dental development and anomalies
  • Anesthesia and Sedative Agents
  • Laser Applications in Dentistry and Medicine
  • Bone health and treatments
  • Bone and Dental Protein Studies
  • Histiocytic Disorders and Treatments
  • Facial Nerve Paralysis Treatment and Research
  • Head and Neck Surgical Oncology
  • Oropharyngeal Anatomy and Pathologies
  • Oral and gingival health research
  • Protease and Inhibitor Mechanisms
  • Cleft Lip and Palate Research
  • Cancer-related molecular mechanisms research
  • Dental Trauma and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Vestibular and auditory disorders
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Complementary and Alternative Medicine Studies
  • Dental Research and COVID-19

Adıyaman University
2015-2023

Afyon Kocatepe University
2018

National Medical Research Center of Dentistry and Maxillofacial Surgery
2015

Dicle University
2013-2015

Inonu University
2015

In current study we aimed to examine the effect of a low-level laser therapy on pain, mouth opening and swelling patients whose impacted 3rd molar tooth was extracted in addition measurement volumetrically edema with 3dMD face system. It surveyed 15 who had bilateral symmetric lower molars. Surgical sides were randomly separated into two groups: group control group. applied extra oral (LLLT, 0.3 W, 40 s, 4 J/cm2) (n = 15) after surgical operation 2nd day. Only routine postoperative...

10.1186/s13005-016-0121-1 article EN cc-by Head & Face Medicine 2016-07-26

Purpose: This study aimed to evaluate the effect of a low-level laser therapy (LLLT) on pain, trismus, and swelling patients whose impacted 3rd molar tooth was extracted compared placebo or “sham” treatment measure volumetrically edema with three-dimensional (3D) surface imaging device (3dMD face system). Materials Methods: Forty-five over 17 years age were included in study. Patients randomized three groups; Group 1, control group, received only routine management (ice application) (n =...

10.4103/njcp.njcp_38_18 article EN Nigerian Journal of Clinical Practice 2018-01-01

To evaluate the efficacy of Kinesio taping (KT) in patients with sleep bruxism (SB) and to determine whether KT may be an alternative for occlusal splint (OS) treatment SB.Sixteen SB were treated (kinesio group) 18 OS (splint group). Masseter temporal muscle pressure pain thresholds (MPPT TPPT), visual analogue scale (VAS) values mouth opening measurements compared before treatment, at 1st 5th weeks treatment.Both treatments significantly reduced pain, decreased VAS values, increased...

10.3233/bmr-181329 article EN Journal of Back and Musculoskeletal Rehabilitation 2018-11-20

Isolated hypodontia is the most common human malformation. It caused by heterozygous variants in various genes, with WNT10A being cause. and WNT10B are paralogs that likely evolved from a ancestral gene after its duplication. Recently, an association of oligodontia (severe tooth agenesis) has been reported. We performed mutational analysis our cohort 256 unrelated Thai families kinds isolated dental anomalies. In 7 afflicted anomalies we detected 4 missense . whole exome sequencing patients...

10.1111/cge.13218 article EN Clinical Genetics 2018-01-24

To examine the effects of caffeic acid phenethyl ester (CAPE; a component honey bee-hive propolis with antioxidant, anti-inflammatory, antiviral and anticancer properties) on bone regeneration fibrotic healing in rat model.Male Sprague-Dawley rats (n = 63; mean age 7 weeks; weight 280-490 g) were randomly divided into three groups: A, cranial defect no treatment 21); B, treated CAPE C, β-tricalcium phosphate/hydroxyl apatite 21). Rats anaesthetized ketamine (8 mg/100 by intraperitoneal...

10.1177/0300060513490613 article EN cc-by-nc Journal of International Medical Research 2013-09-24

The aim of the present study was to evaluate and compare effects single‑ two‑dose low-level laser therapy (LLLT) on postoperative swelling, trismus pain patients undergoing extraction impacted mandibular third molars. In addition, edema volumetrically measured with a 3dMD face system. A total 45 were randomly divided into three treatment groups (15 in each group) as follows: Group 1, receiving routine management ice application serving control group; 2, single dose LLLT immediately following...

10.3892/etm.2018.5921 article EN Experimental and Therapeutic Medicine 2018-03-02

Abstract Background Temporomandibular joint osteoarthritis (TMJ-OA) is a degenerative disease and manifests itself with pain limitation of movement in the jaws. Arthrocentesis alone or combination intraarticular injections one most commonly used treatment methods these patients. The aim study to examine effectiveness arthrocentesis plus tenoxicam injection compare it patients TMJ-OA. Methods Thirty TMJ-OA who were treated randomly either (TX group) (control examined. Maximum mouth opening...

10.1186/s12903-023-02852-z article EN cc-by BMC Oral Health 2023-03-08

Background:Oral breathing causes many changes in the facial anatomical structures adult patients. In this study we aimed to determine effects of long-term oral (>5 years) on maxillary sinus volumes among male Material andMethods:We accessed medical records 586 patients who had undergone cone beam computed tomography (CBCT) for any reason between September 2013 and April 2014. Patients cone-beam dental volumetric scans answered a questionnaire about were screened retrospectively. Cone (I-Cat,...

10.12659/msm.891371 article EN Medical Science Monitor 2015-01-01

Introduction: In this study, we investigated the effects of long-term antihypertensive treatment with calcium channel blockers or beta on bone mineral density maxilla, as determined by cone-beam computed tomography (CBCT). Material and methods: This retrospective study was conducted CBCT images men older than 55 years who had received different dental indications. Data were grouped into three categories according to medication history patients: group A included patients been taking...

10.2147/cia.s60669 article EN cc-by-nc Clinical Interventions in Aging 2014-03-01

The aim of this article is to emphasize that the accidental displacement a lower third molar during extraction rare, but potentially serious complication. We present two case reports on tooth dislodged into submandibular space following its removal from sockets and subsequent management rare Differences in direction displacement, size fragment, delay retrieval, tissue reactions can all influence potential complication hence no one technique uniformly applicable. Though complication,...

10.4103/0976-9668.136274 article EN Journal of Natural Science Biology and Medicine 2014-01-01

The aim of this study is to determine the reliability panoramic radiograph (PR) as a screening tool for detection calcified carotid atheroma (CCA) by comparing it with Doppler ultrasonography (DU) examination. A second was evaluate relationship among CCA, systemic diseases, smoking, and body mass index in an older population.A total 1,650 PRs patients aged over 45 years (736 males 914 females) were randomly selected. All had been referred Faculty Dentistry, Afyon Kocatepe University,...

10.2147/cia.s84683 article EN cc-by-nc Clinical Interventions in Aging 2015-07-01

Objective: The present study aimed to evaluate the anxiety and optical coherence tomography (OCT) findings in patients with sleep bruxism (SB) develop objective measurements assess neurodegenerative inflammatory processes associated this disease.Methods: A group of 40 SB were compared a control consisting healthy individuals (without SB). Anxiety results OCT retinal nerve fiber layer (RNFL), ganglion cell (GCL), inner plexiform (IPL), choroidal thickness assessed both groups.Results: values...

10.1080/08869634.2018.1543829 article EN CRANIO® 2018-11-08

Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) disease is rare, but there are serious side-effects BP therapy in patients. In some patients, surgery needed and could not be cured. A standard test available showing risk routine use. The measurement serum C-terminal telopeptide (CTX) levels has been used diseases BRONJ resorption antiresorptive therapy.This paper aimed at investigating relationship between traumatic procedures presence BP-related osteonecrosis.Thirty male Wistar...

10.4103/1119-3077.141417 article EN Nigerian Journal of Clinical Practice 2014-01-01

In this study, it was aimed to histologic and immunohistochemical examined that the effects of quercetin on new bone formation regeneration in critical size rat tibial defects. 56 rats were divided into 4 groups with 14 each group. Control (C) (n = 14): A defect created corticocancellous metaphyseal part tibia bones no additional procedure applied until end experimental setup. Xenograft (X) group Bone defects filled xenograft. No process Quercetin (Q) 0.1 mg/kg administered by oral gavage...

10.1016/j.jobcr.2022.10.008 article EN cc-by-nc-nd Journal of Oral Biology and Craniofacial Research 2022-10-31

The aim of this study was to evaluate the effects melatonin healing in a tibial bone defect model rats by means histopathological and immunohistochemistry analysis.Twenty one male Wistar albino were used study.In each animal, defects (6 mm length ) created tibias.The animals divided into three groups.In group 1 control (rats which defects).Group 2 (10 mg/kg) + 14 days group) administered intraperitoneally rats.Group 3 28 rats.Histopathological analysis samples performed process osteoblastic...

10.4067/s0717-95022016000200053 article EN International Journal of Morphology 2016-06-01

Objective: To investigate serum prolidase activity and oxidative stress in patients with temporomandibular joint internal derangement (TMJ-ID).Methods: Seventy Wilkes stage III, IV, V joints 70 healthy controls were included. Serum parameters, including total antioxidant status (TAS), oxidant (TOS), index (OSI), advanced oxidation protein products (AOPP), glutathione (GSH), ferric reducing power (FRAP), lipid hydroperoxide (LOOH) measured.Results: The levels of prolidase, TOS, OSI, AOPP,...

10.1080/08869634.2019.1606987 article EN CRANIO® 2019-04-25

Aims and Objective: Sleep bruxism is a complicated disease, its cause remains controversial. If the etiology of resolved, treatment can be adjusted to prevailing aetiological factor. Thus, aim this study was evaluate oxidative stress level serum prolidase activity in patients with sleep bruxism. Materials Methods: Seventy healthy subjects 51 were included study, blood samples from all collected. Serum analyzed for total antioxidant status (TAS), oxidant (TOS), index (OSI), activity. Results:...

10.2174/1386207323999200729114410 article EN Combinatorial Chemistry & High Throughput Screening 2020-07-30

Background Understanding the pathogenesis of temporomandibular joint disorder (TMD) is important for diagnosis and treatment planning. Thus, biochemical analysis usually used detection tissue damage. Objective In this study, we aimed to investigate serum asporin levels in patients with TMD. Methods Our study was planned be performed on 43 healthy individuals (control group) without any problems internal derangement (TMJ-ID; according Wilkes classification (stages 3, 4 5). Serum were...

10.1111/joor.13234 article EN Journal of Oral Rehabilitation 2021-07-26

Objective: Diode laser and ozone can be used to healing of skin wounds.The aim this study is evaluate the biostimulatory effects diode on sutured wounds in rats.Materials Methods: In study, 21 adult males Wistar albino rats were used.Three 1-cm-longs, full-thickness incisions applied back each animal closed with sutures.Diode treatment, irrigation 0.9% saline solution therapy was through 7 days.Animals euthanized 3 rd , th 14 days after all surgically removed for histopathological...

10.4274/meandros.97269 article EN Meandros Medical And Dental Journal 2018-08-01
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