Víctor M. Muñoz-Pérez

ORCID: 0000-0003-1820-0839
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About
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Research Areas
  • Preterm Birth and Chorioamnionitis
  • Reproductive System and Pregnancy
  • Pregnancy-related medical research
  • Pain Mechanisms and Treatments
  • Hibiscus Plant Research Studies
  • Pregnancy and Medication Impact
  • Medicinal plant effects and applications
  • Ethics and bioethics in healthcare
  • Reproductive Physiology in Livestock
  • Health and Medical Education
  • Ion channel regulation and function
  • Ergonomics and Musculoskeletal Disorders
  • Genomics, phytochemicals, and oxidative stress
  • Antibiotic Use and Resistance
  • Psidium guajava Extracts and Applications
  • Cancer Immunotherapy and Biomarkers
  • Anesthesia and Pain Management
  • Cancer Treatment and Pharmacology
  • Hallucinations in medical conditions
  • Liver Disease Diagnosis and Treatment
  • Liver physiology and pathology
  • Phytochemistry and Biological Activities
  • Pharmacological Effects of Natural Compounds
  • COVID-19 Impact on Reproduction
  • Infant Nutrition and Health

Universidad Autónoma del Estado de Hidalgo
2017-2025

Introduction: This work aimed to evaluate the anti-inflammatory and myorelaxant effect of thymol (TM) carvacrol (CAR) in pregnant rat uterus. Both compounds exhibit considerable antimicrobial, antispasmodic, effects due these properties, they were studied this vitro model premature birth induced by infection. Method: All uterine tissues contraction tests determine inhibitory TM, CAR (10, 56, 100, 150, 230 μM), nifedipine (a calcium channel antagonist) on phasic tonic electro-...

10.2174/0118761429342128241231163610 article EN cc-by Current Molecular Pharmacology 2025-01-09

Background: Hibiscus sabdariffa is a plant used in traditional medicine for intestinal treatments and nowadays critical diseases like hypertension, diabetes, cancer. Multidisciplinary approaches have demonstrated, through extracts, anti-inflammation anti-cancer beneficial properties from compounds phenols, flavonoids, anthocyanins that are ubiquitously distributed whole plants. Objective: The objective of this study to identify the bioactive their underlying mechanisms action drive...

10.2174/0122103155352510241218055748 article EN The Natural Products Journal 2025-01-23

Background/Objectives: Carvacrol is a naturally occurring phenolic monoterpene that one of the major constituents essential oils oregano (Origanum vulgare), thyme (Thymus vulgaris) and other herbs. has anti-inflammatory antinociceptive effects. At systemic level, carvacrol able to activate inhibit several second messengers ion channels. However, there no evidence on peripheral antinociception its probable mechanism action. The aim this study was investigate whether local involves opioid...

10.20944/preprints202504.0900.v1 preprint EN 2025-04-10

There is an urgent need for scientists to verify the pharmacological properties of medicinal plants. Leucophyllum frutescens (Lf) belongs family Scrophulariaceae, and it used in treatment airway diseases such as cough, tuberculosis, asthma. The methanolic extract aerial parts Lf allows isolation identification verbascoside (Vb). This study aimed evaluate hepatoprotective effect Vb, a caffeoyl phenylethanoid glycoside (CPG), on post-necrotic liver damage induced by thioacetamide (TA) via vivo...

10.3390/scipharm91030040 article EN cc-by Scientia Pharmaceutica 2023-08-16

The aim of this study was to evaluate the in vitro anti-inflammatory and utero-relaxant effect α-bisabolol on pregnant human myometrium. Samples from myometrium were used functional tests inhibitory (560, 860, 1,200 1,860 µM) spontaneous myometrial contractions. intracellular cyclic adenosine monophosphate (cAMP) levels generated response homogenates measured by ELISA. determined through measurement two pro-inflammatory cytokines, tumor necrosis factor-α (TNFα) interleukin (IL)-1β, cytokine...

10.4196/kjpp.2018.22.4.391 article EN Korean Journal of Physiology and Pharmacology 2018-01-01

Objective To determine the prevalence and features of self-medication (SM) in Mexican populations. Data Sources An electronic bibliographic search was carried out from databases indexing services including Scopus, PubMed, International Pharmaceutical Abstracts (Clarivate Analytics), Embase, Web Science Google Scholar addressing SM practice populations, with allopathic or conventional medicines (CM) complementary alternative medicine (CAM), (diseases-related, factors-associated, drugs). Study...

10.4140/tcp.n.2022.266 article EN The Senior Care Pharmacist 2022-06-26

The aim of this study was to evaluate the relaxant and anti-inflammatory effects two thalidomide analogs as phosphodiesterase-4 (PDE-4) inhibitors in pregnant rat uterus. Uteri from Wistar female rats were isolated at 19 day pregnancy. Uterine samples used functional studies inhibitory analogs, methyl 3-(4-nitrophthalimido)-3-(3,4-dimethoxyphenyl)-propanoate (4NO2PDPMe) 3-(4-aminophthalimido)-3-(3,4-dimethoxyphenyl)-propanoate (4APDPMe), on prostaglandin-F2α (PGF2α)-induced phasic,...

10.4196/kjpp.2017.21.4.429 article EN Korean Journal of Physiology and Pharmacology 2017-01-01

Abstract Background Premature infants contribute to infant morbidity and mortality especially in low resource settings. Information on tocolytic and/or anti‐inflammatory effects of several plant extracts, such as citral, could help prevent preterm birth cases reduce the number infants. The aim this study was evaluate vitro effect citral myometrial tissues human uterus. Methods Myometrial samples from uteri obtained after hysterectomy were used functional tests inhibitory PGF‐2α induced...

10.1002/bdr2.1873 article EN Birth Defects Research 2021-01-23

Despite the wide application of carvacrol (CAR) in different biological and medical areas, there is still insufficient electrophysiological data on mechanisms action CAR, particularly pregnant uterine function. The aim this study was to evaluate vitro tocolytic effect CAR contractility isolated rat uterus presence a calcium channel antagonist (nifedipine) cyclooxygenase inhibitor (indomethacin). uteri were from Wistar rats at 16–18 days pregnancy suspended an organ bath chamber containing...

10.4103/cjp.cjp_56_20 article EN cc-by-nc-sa The Chinese Journal of Physiology 2020-01-01

The objective of the present study was to scrutinize effect nitric oxide (NO), cyclic GMP (cGMP), potassium channel blockers, and metformin on citral-produced peripheral antinociception. rat paw 1% formalin test used assess nociception Rats were treated with local administration citral (10–100 µg/paw). antinociception (100 µg/paw) evaluated without pretreatment naloxone, NG-L-nitro-arginine methyl ester (L-NAME, a NO synthesis inhibitor), 1H-(1,2,4)-oxadiazolo(4,2-a)quinoxalin-1-one (ODQ,...

10.1139/cjpp-2021-0458 article EN Canadian Journal of Physiology and Pharmacology 2021-11-26

Inflammation plays an important role to the development of cancer and promotes all stages tumorigenesis. Cancer cells, as well inflammatory carry out reciprocal interactions form tumor microenvironment (TME). cells within TME are highly able change their phenotypic functional characteristics. Here, we review relationship between inflammation infection in origins, mechanisms whereby drive formation. We discuss how tumorigenesis related processes typically found autoimmune diseases, release...

10.29057/mjmr.v10i19.8112 article EN Mexican Journal of Medical Research ICSA 2022-01-05

The aim of this study was to examine if the peripheral antinociception α-bisabolol involves participation nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) synthesis followed by K+ channel opening in formalin test. Wistar rats were injected dorsal surface right hind paw with (1%). Rats received a subcutaneous injection into vehicles or increasing doses (100-300 µg/paw). To determine whether induced mediated either opioid receptors NO-cGMP-K+ channels pathway, effect pretreatment...

10.1139/cjpp-2020-0744 article EN Canadian Journal of Physiology and Pharmacology 2021-04-15

La genética ha evolucionado enormemente el desarrollo de las ciencias la salud. Desde los trabajos Mendel hasta tener gran impactado en progreso tecnología actual para diagnóstico, seguimiento y tratamiento enfermedades origen genético. Además constituye bases estructura, entendimiento del genoma humano variabilidad su expression, como sustento mantener estado homeostasis sinónimo salud física mental.

10.29057/icsa.v8i15.4803 article ES Educación y Salud Boletín Científico Instituto de Ciencias de la Salud Universidad Autónoma del Estado de Hidalgo 2019-12-05

Propósito. Esta revisión sistemática investiga la prevalencia de miopía, hipermetropía y astigmatismo en población mexicana, incluidos todos los grupos edad. Métodos. Se realizó una búsqueda detallada a partir estudios que reportaron errores refractivos (ER), cualquier parte del México las siguientes bases datos: Scopus, PubMed, Cochrane, Medline, Web of Science Google Scholar. Resultados. incluyeron un total 21 manuscritos el análisis final. En se 688,893 sujetos (de 0 90 años). cuanto al...

10.29057/icsa.v10i20.8591 article ES Educación y Salud Boletín Científico Instituto de Ciencias de la Salud Universidad Autónoma del Estado de Hidalgo 2022-06-05

Antecedentes. Durante la gestación, respuesta inmunitaria de placenta hacía los virus y otros patógenos juega un papel importante en determinación vulnerabilidad una mujer embarazada frente a diversas enfermedades infecciosas como zika, ébola, herpes simple papiloma humano. En interfaz materno-fetal, las células trofoblásticas, deciduales, interferones, proteínas moléculas proinflamatorias, sirven para minimizar mitigar propagación entre madre el feto desarrollo través complejo sistema...

10.29057/icsa.v10i20.7574 article ES Educación y Salud Boletín Científico Instituto de Ciencias de la Salud Universidad Autónoma del Estado de Hidalgo 2022-06-05
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