Inflammation is the immune system’s first biological response to infection, injury, or irritation. Evidence suggests that anti-inflammatory effect mediated by regulation of various inflammatory cytokines, such as nitric oxide, interleukins, tumor necrosis factor alpha-α, interferon gamma-γ, well non-cytokine mediator, prostaglandin E2. Currently, mechanism action and clinical usefulness phytochemicals known; their on activity free radicals, oxidative stress. The latter are great relevance in...

Commercialization of cactus pears based on their antioxidant properties can generate competitive advantages, and these turn into business opportunities the development new products a high-value ingredient for food industry. This work evaluated activities (1,1-diphenyl-2-picrylhydrazyl radical-scavenging, protection against oxidation β-carotene-linoleic acid emulsion, iron (II) chelation), content total phenolic compounds, ascorbic acid, betacyanin, betaxanthin stability betacyanin pigments...

Pomegranate is a polyphenol-rich fruit. Studies have shown that extracts prepared from its juice or different parts of the pomegranate plant various biological activities including antioxidant, antimicrobial, anti-inflammatory, anticarcinogenic, cardioprotective, and antidiabetic. The therapeutic potential has been attributed to phytochemicals, ellagic acid, punicic flavonoids, anthocyanidins, anthocyanins, flavonols, flavones. This review focuses on scientific evidence as hypoglycemic,...

Recent studies have shown that handcrafted glass-clay containers are a health risk because they can be contaminated by heavy metals, which transferred to food, thus reaching the human body potentially cause illness. Therefore, in present work, we evaluate leaching of lead, cadmium, and cobalt from into two types food: tomato sauce (salsa), chickpea puree. The were obtained four regions Mexican state Hidalgo. Repetitive extractions carried out quantify metals salsa, puree, acetic acid using...

Rice bean is a legume that considered to be an important source of protein; it still poorly understood but can produce peptides with various biological activities. These released by enzymes during gastrointestinal passage and have physiological effect on cancer cells. Since both the type enzyme cocktail used are crucial for production against certain cell types, anticancer effects Vigna umbellata isolate hydrolysate MDA SiHa cells were investigated in this study. The was obtained via...

Amaranth seeds, although a valuable food in Mexico, contain anti-nutritional compounds that can affect quality. As part of this work, the proximate composition, fatty acid profile, protein digestibility, and effect germination popping Amaranthus hypochondriacus seeds was analyzed with aim eliminating compounds. Untreated comprised 11.35-18.8% 0.27-13.39% lipids, including omega 3, 6, 9 acids such as oleic, linoleic, linolenic, arachidonic acid. The main minerals detected were Ca+2, K+1,...

There is an urgent need for scientists to verify the pharmacological properties of medicinal plants. Leucophyllum frutescens (Lf) belongs family Scrophulariaceae, and it used in treatment airway diseases such as cough, tuberculosis, asthma. The methanolic extract aerial parts Lf allows isolation identification verbascoside (Vb). This study aimed evaluate hepatoprotective effect Vb, a caffeoyl phenylethanoid glycoside (CPG), on post-necrotic liver damage induced by thioacetamide (TA) via vivo...

Lectins comprise a heterogeneous class of proteins that recognize the carbohydrate moieties glycoconjugates with high specificity. Numerous studies have shown lectins are capable recognizing specific displayed by malignant cells or tissues. The present work was performed to investigate effects tepary bean (Phaseolus acutifolius) on proliferation, colony formation, and alteration DNA synthesis human cells. Tepary lectin showed dose dependent inhibition viability as well formation in two lines...

Fluoride is naturally present in the earth's crust and can be found rocks, coal, clay; thus, it small quantities water, air, plants, animals. Therefore, humans are exposed to fluoride through food, drinking air they breathe. Flouride essential maintain bone strength protect against dental decay, but if absorbed too frequently, cause tooth osteoporosis, damage kidneys, bones, nerves, muscles. work was aimed at determining effect of intake sodium (NaF) as an apoptosis inducer leukocytes rats...

The present work shows the characterization of Phaseolus acutifolius variety latifolius, on which little research has been published, and provides detailed information corresponding lectin. This protein was purified from a semi-domesticated line white tepary beans Sonora, Mexico, by precipitation aqueous extract with ammonium sulfate, followed affinity chromatography an immobilized fetuin matrix. MALDI TOF analysis agglutinin (PAA) showed that this lectin is composed monomers molecular...

There are few reports that demonstrate the antigenotoxic potential of cranberries. Although types berry fruits consumed worldwide many, this paper focuses on cranberries commonly in Mexico (Vaccinium macrocarpon species). The purpose present study is to determine whether cranberry ethanolic extract (CEE) can prevent DNA damage produced by benzo[a]pyrene (B[a]P) using an vivo mouse peripheral blood micronucleus assay. experimental groups were organized as follows: a negative control group...

In this study, a partial purification and characterization of the lectins from two varieties Phaseolus coccineus (black purple ayocote bean) was carried out. A performed by affinity chromatography on fetuin-agarose. The lectins’ showed that hemagglutination activity only inhibited fetuin saccharides (mono-, di- tri-saccharides) do not influence their capacity. difference in relative molecular weight between observed, 28.5 kDa for black variety 30.6 variety. both varieties, ions were detected...

For many years, several studies have been employing lectin from vegetables in order to prove its toxic effect on various cell lines. In this work, we analyzed the cytotoxic, antiproliferative, and post-incubatory of pure tepary bean lectins four lines malignant cells: C33-A; MCF-7; SKNSH, SW480. The tests were carried out MTT 3[H]-thymidine assays. results showed that after 24 h exposure, cells a dose-dependent cytotoxic effect, being higher MCF-7, while C33-A highest resistance. Cell...

Bauhinia forficata L. is a tree used in alternative medicine as an anti-diabetic agent, with little scientific information about its pharmacological properties. The hypoglycemic, antioxidant, and genoprotective activities of methanolic extract B. leaves stems combined were investigated mice treated streptozotocin (STZ). Secondary metabolites determined by qualitative phytochemistry. In vitro antioxidant activity was the DPPH method at four concentrations extract. evaluated 3 groups mice:...

Amaranth has been of interest for its nutritional quality and multiple benefits; however, there is little research on toxicological effect. This work studied antinutritional compounds, the cytotoxic genotoxic effect in Amaranthus protein extract (PEAh). The content lectins, tannins, saponins, trypsin inhibitors was determined. Biological studies were conducted to determine toxicity male CD-1 mice by intraperitoneal administration. potential determined micronucleus test. bone marrow...

It is well known that gadolinium chloride (GD) attenuates drug-induced hepatotoxicity by selectively inactivating Kupffer cells. In the present study effect of GD in reference to cell cycle and postnecrotic liver regeneration induced thioacetamide (TA) rats was studied. Two months male rats, intraveously pretreated with a single dose (0.1 mmol/Kg), were intraperitoneally injected TA (6.6 mmol/Kg). Samples blood obtained from at 0, 12, 24, 48, 72 96 h following intoxication. Parameters...

Undernutrition induces an increase of the oxidative stress that can predispose offspring to various diseases in adulthood through epigenetic reprogramming. The aim this study was evaluate effects intergenerational undernutrition on protein oxidation and antioxidant defence response liver, heart brain second-generation neonates (F2 ) undernourished rats. For purpose, both parents parental (F0 first generation (F1 were fed with a low-nutrient diet. Body mass length decreased (p < 0.05) F0 , F1...

According to the available ethnobotanical data, Bouvardia ternifolia plant has long been used in Mexican traditional medicine relieve symptoms of inflammation. In present study, cytotoxic effect extracts obtained from flowers, leaves and stems B. using hexane, ethyl acetate (AcOEt) methanol (MeOH) was evaluated by applying them SiHa MDA-MB-231 cancer cell lines. An MTT reduction assay carried out along with = biological activity assessments, content total phenols, tannins, anthocyanins,...

The damage caused by chronic alcohol consumption is frequently reported, but the effects weekend recreational consumption, which much more frequent than even daily have not, to our knowledge, been reported. metabolism of ethanol, once consumed, starts from mouth, and biotransformation process follows different routes. In this study, effect on oral cavity was observed. Methods: Thirty male female rats were divided into six groups (n = 5), with control (male/female) administered 5% 40% ethanol...

Context: Heliopsis longipes (A. Gray) Blake (Asteraceae), a plant native to Mexico, is used in traditional medicine as analgesic and microbicide. The main component the H. ethanolic extract (HLEE) affinin, determined by HPLC/UV–visible NMR measurement. To date, there no documented evidence on spermicidal activity of this extract.