Kyle Fluegge

ORCID: 0000-0003-1822-4224
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About
Contact & Profiles
Research Areas
  • Tuberculosis Research and Epidemiology
  • Attention Deficit Hyperactivity Disorder
  • Air Quality and Health Impacts
  • Healthcare Policy and Management
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Hepatitis C virus research
  • Mycobacterium research and diagnosis
  • Pneumonia and Respiratory Infections
  • Health Systems, Economic Evaluations, Quality of Life
  • Health, Environment, Cognitive Aging
  • Pesticide Exposure and Toxicity
  • Primary Care and Health Outcomes
  • Climate Change and Health Impacts
  • Global Maternal and Child Health
  • Diagnosis and treatment of tuberculosis
  • Health disparities and outcomes
  • Chronic Disease Management Strategies
  • Maternal Mental Health During Pregnancy and Postpartum
  • Cultural Competency in Health Care
  • Medication Adherence and Compliance
  • Employment and Welfare Studies
  • Pesticide and Herbicide Environmental Studies
  • Data-Driven Disease Surveillance
  • Alzheimer's disease research and treatments
  • Nutritional Studies and Diet

Ohio Department of Health
2014-2025

New York City Department of Health and Mental Hygiene
2016-2021

Case Western Reserve University
2015-2020

Cleveland Research (United States)
2016-2018

Wellcome / EPSRC Centre for Interventional and Surgical Sciences
2018

Josef Meissner (Germany)
2018

Wyatt Technology (China)
2018

University School
2015-2016

Agricultural & Applied Economics Association
2016

The Ohio State University
2011-2015

Genetic studies of both the human host and Mycobacterium tuberculosis (MTB) demonstrate independent association with (TB) risk. However, neither explains a large portion disease risk or severity. Based on in other infectious diseases animal models TB, we hypothesized that genomes two interact to modulate developing active TB increasing severity disease, when present. We examined this hypothesis our household contact study Kampala, Uganda, which there were 3 MTB lineages L4-Ugandan (L4.6) is...

10.1371/journal.pgen.1008728 article EN cc-by PLoS Genetics 2020-04-30

This study assessed the impact of individual social risk factor variables and determinants health (SDOH) measures on hospital readmission rates penalties used in Centers for Medicare Medicaid Services (CMS) Hospital Readmissions Reduction Program (HRRP). Using 2012–16 discharge data from New York City, we projected HRRP by augmenting CMS's model heart attack, failure, pneumonia with SDOH scores constructed at each four geographic levels a measure individual-level risk. Including additional...

10.1377/hlthaff.2020.01742 article EN Health Affairs 2021-04-01

The authors have published their findings that simufilam, a small novel molecule suggested for clinical use in Alzheimer’s disease (AD), restores deleterious conformation of filamin A (FLNA), which is large intracellular scaffolding protein, as indicated by changes isoelectric focusing points [...]

10.3390/ijms26062480 article EN International Journal of Molecular Sciences 2025-03-11

There has been considerable international study on the etiology of rising mental disorders, such as ADHD, in human populations.As glyphosate is most commonly used herbicide world, we sought to test hypothesis that use agriculture may be a contributing environmental factor increase healthcare utilization among individuals with diagnosed ADHD.State estimates for and nitrogen fertilizer were obtained from USGS.We queried Healthcare Cost Utilization Project net (HCUPNET) state-level...

10.15244/pjoes/61742 article EN Polish Journal of Environmental Studies 2016-01-01

Both prenatal organophosphate (OP) and pyrethroid (PYRE) insecticide exposures have been inconsistently linked with poorer neurodevelopmental outcomes. However, given that neither exposure occurs in isolation, both classes are neurotoxic, it is important to consider when evaluating these Employing biomarkers of pesticide exposure, this research describes the effects urinary metabolite levels PYRE OP insecticides, measured second third trimesters pregnancy postnatal at 2 months age, on child...

10.5281/zenodo.218417 article EN PubMed 2016-05-01

Community water fluoridation is considered a significant public health achievement of the 20th century. In this paper, hypothesis that added has contributed to diabetes incidence and prevalence in United States was investigated. Panel data from publicly available sources were used with population-averaged models test associations natural fluoride on outcomes at county level 22 states for years 2005 2010. The findings suggest 1 mg increase mean significantly positively predicts 0.23 per 1,000...

10.2166/wh.2016.012 article EN Journal of Water and Health 2016-05-24

Appraisal delay is the time a patient takes to consider symptom as not only noticeable, but sign of illness. The study's objective was determine association between appraisal in seeking tuberculosis (TB) treatment and geographic distance measured by network travel (driving pedestrian) (in minutes) (Euclidean self-reported) kilometers) identify other risk factors from selected covariates how they modify core distance.This part longitudinal cohort study known Kawempe Community Health Study...

10.1186/s12889-018-5648-6 article EN cc-by BMC Public Health 2018-06-26

There has been considerable international study on the etiology of rising mental disorders, such as attention-deficit hyperactivity disorder (ADHD), in human populations. As glyphosate is most commonly used herbicide world, we sought to test hypothesis that use agriculture may be a contributing environmental factor rise ADHD State estimates for and nitrogen fertilizer were obtained from U.S. Geological Survey (USGS). We queried Healthcare Cost Utilization Project net (HCUPNET) state-level...

10.1371/journal.pone.0133525 article EN cc-by PLoS ONE 2015-08-19

ABSTRACT The link between various air pollutants and hospitalization for epilepsy has come under scrutiny. We have proposed that exposure to pollution specifically the pervasive agricultural pollutant greenhouse gas, nitrous oxide (N2O), may provoke susceptibility neurodevelopmental disorders. Evidence supports a role of N2O in reducing epileptiform seizure activity, while withdrawal from drug been shown induce seizure-like activity. Therefore, we show here statewide use anthropogenic...

10.1590/0004-282x20170107 article EN cc-by-nc Arquivos de Neuro-Psiquiatria 2017-09-01

This Study explores Somali and Ethiopian community leaders’ perceptions about health issues in their communities the barriers to access utilization of primary care services. Fourteen in-depth interviews were conducted with leaders thematic analysis was used analyze interviews. Participants identified chronic diseases, unhealthy behaviors associated them, mental as major issues. Infectious diseases secondarily mentioned important concerns. Lack insurance limited understanding system viewed...

10.5195/hcs.2014.113 article EN Health Culture and Society 2014-05-19

OBJECTIVE: To calculate the per-session and annual direct program costs to implement directly observed therapy (DOT) for tuberculosis treatment conduct a cost attribution analysis under varying proportions of DOT utilization four types.DESIGN: Program data covering study period from September 2014 August 2015 in New York City (NYC) were used retrospective bottom-up micro-costing economic evaluation. For each type, potential savings estimated as averted by adopting uniform distribution...

10.5588/ijtld.18.0625 article EN The International Journal of Tuberculosis and Lung Disease 2019-11-01

Objective: To estimate the cost of delivering a hepatitis C virus care coordination program at 2 New York City health provider organizations and describe potential payment model for these currently nonreimbursed services. Design: An economic evaluation was conducted using micro-costing methods compared with macro-costing methods. A calculated 3 phases: enrollment to treatment initiation, initiation completion, bonus laboratory evidence successful outcome (sustained viral response). Setting:...

10.1097/phh.0000000000000806 article EN Journal of Public Health Management and Practice 2018-07-03

Abstract Objective Individual adherence to a 9‐month regimen of isoniazid (9 INH ) for treatment latent tuberculosis infection ( LTBI was hypothesized reflect prevalent elastic health behavior pattern, or prevention correlated with relevant disease burden. Method Log‐rank tests were used compare survival functions among raw prevalence tertiles diseases including TB , diabetes, and obesity. Own cross‐prevalence elasticities calculated spatially characterized behavioral response that may...

10.1111/phn.12170 article EN Public Health Nursing 2015-02-06

I sought to determine how medical comorbidities co-exist with incident psychiatric condition.I used data from all 11 available waves (1992-2012) of the Health and Retirement Study (HRS). identified 4,358 index participants self-reported condition. collected comorbidity preceding, including, succeeding that wave. Comorbidities assessed included high blood pressure (HBP), diabetes mellitus, cancer, lung disease, heart stroke, arthritis. Modified Poisson regression combined log-linked binomial...

10.1177/2333721416635001 article EN cc-by-nc Gerontology and Geriatric Medicine 2016-01-01

Abstract The New York City Department of Health and Mental Hygiene (DOHMH) implemented Project INSPIRE, an integrated model hepatitis C care coordination telementoring services, from 2014 to 2017. We evaluated the use chronic management (CCM) codes sustain intervention. DOHMH data were collected as part a Healthcare Innovation Award Centers for Medicare & Medicaid Services (CMS). A retrospective cohort medical billing study was conducted by assigning INSPIRE activities procedure in both...

10.1002/jhrm.21389 article EN Journal of Healthcare Risk Management 2019-08-30

Abstract Genetic studies of both the human host and Mycobacterium tuberculosis (MTB) demonstrate independent association with (TB) risk. However, neither explains a large portion disease risk or severity. Based on in other infectious diseases animal models TB, we hypothesized that genomes two interact to modulate developing active TB increasing severity disease, when present. We examined this hypothesis our household contact study Kampala, Uganda, which there were 3 MTB lineages L4-Ugandan...

10.1101/769448 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-09-14

The incorporation of genetics into health services research has largely floundered, despite the rapidly accelerating availability of, and access to, such data. This is expected given ethical questions involved. However, using these new resources robustly to examine population choices when it comes insurer selection, coverage therein especially subsequent use a necessary step forward, increasing prevalence multimorbidity. Such novel advancement in may eventually propel public private insurers...

10.1177/1355819616664374 article EN Journal of Health Services Research & Policy 2016-11-03
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