A5007576693- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Poxvirus research and outbreaks
- Virology and Viral Diseases
- Pharmaceutical studies and practices
- Antibiotic Use and Resistance
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- COVID-19 epidemiological studies
- Bartonella species infections research
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Migration, Health and Trauma
- Hepatitis Viruses Studies and Epidemiology
- Long-Term Effects of COVID-19
- Healthcare cost, quality, practices
- Viral Infections and Vectors
- Pharmaceutical Economics and Policy
- vaccines and immunoinformatics approaches
- Food Security and Health in Diverse Populations
- Health Systems, Economic Evaluations, Quality of Life
New York City Department of Health and Mental Hygiene
2014-2025
AID Atlanta
2024
San Francisco Department of Public Health
2020
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
2020
Centers for Disease Control and Prevention
2017
Spina Bifida Association
2017
Texas Department of State Health Services
2006
Directly observed therapy (DOT), the standard of care for monitoring patients on treatment tuberculosis (TB), requires substantial health department resources, and can be inconvenient disruptive patients.To determine whether video technology remote observation anti-tuberculosis (VDOT) is as effective in-person DOT.Eligible TB in New York City were prospectively enrolled VDOT from September 2013 to 2014. We compared outcomes worker output DOT.Among 390 DOT TB, 61 (16%) 329 (84%) DOT....
<h3>Importance</h3> Electronic directly observed therapy (DOT) is used increasingly as an alternative to in-person DOT for monitoring tuberculosis treatment. Evidence supporting its efficacy limited. <h3>Objective</h3> To determine whether electronic can attain a level of treatment observation favorable DOT. <h3>Design, Setting, and Participants</h3> This was 2-period crossover, noninferiority trial with initial randomization or at the time outpatient began. The enrolled 216 participants...
Since January 2013, the New York City (NYC) Health Department Tuberculosis (TB) Program has offered persons diagnosed with latent TB infection (LTBI) 3-month, once-weekly isoniazid and rifapentine (3HP) treatment regimen. Patients on this are monitored in-person under directly observed therapy (DOT). To address patient provider barriers to DOT, we piloted use of a videoconferencing software app remotely conduct synchronous DOT (video therapy; VDOT) for patients 3HP.The objective our study...
Since April 2022, more than 220,000 immigrants seeking asylum or other legal status have arrived in New York City from southern U.S. border states. The Department of Homeless Services quickly established a network sanctuary shelters to respond the unprecedented volume newly immigrants. Approximately 37% recent arrivals been children, many with unknown incomplete immunization jeopardizing their compliance city vaccine requirements for school and day care attendance. number children facing...
Abstract Early in the 2022 mpox outbreak, U.S. recommendation was to administer two doses of JYNNEOS® vaccine 4 weeks apart. However, because limited supply, New York City (NYC) prioritized single dose vaccination. We estimated cases averted by this strategy compared strategies that 2-dose vaccination for a smaller portion population. fit network transmission model incident NYC. Model output consisted predicted over time when were administered with ‘first-dose priority’ strategy,...
Background. Completion of treatment for tuberculosis infection (TBI) with 9 months self-administered daily isoniazid (9H) has historically been low (<50%) among New York City (NYC) Health Department clinic patients. Treatment TBI 3 once-weekly and rifapentine (3HP) administered under directly observed therapy (DOT) might increase acceptance completion.
Objectives. To assess costs of video and traditional in-person directly observed therapy (DOT) for tuberculosis (TB) treatment to health departments patients in New York City, Rhode Island, San Francisco, California.Methods. We collected department DOT (VDOT; live recorded), (field- clinic-based). Time-motion surveys estimated provider time cost. A separate survey patient costs. used a regression model estimate cost by type.Results. Between August 2017 June 2018, 343 sessions were captured...
Context: An increasing number of tuberculosis (TB) programs are adopting electronic directly observed therapy (eDOT), the use technology to supervise patient adherence remotely. Pilot studies show that treatment and completion were similar with eDOT compared standard in-person DOT. Objective: In December 2015, National Tuberculosis Controllers Association administered an online survey determine extent which is used in United States. Participants: Sixty-eight Centers for Disease Control...
Four New York City (NYC) Health Department tuberculosis (TB) clinics.To assess the effectiveness of preferentially offering two shorter treatment regimens-4 months daily rifampin (4R) and 3 once-weekly isoniazid rifapentine (3HP)-as an alternative to 9 (9H) for latent tuberculous infection (LTBI).Retrospective analysis patients treated LTBI from January June 2015. Poisson regression with robust standard error was used examine factors associated completion.Of on 9H, 49% (27/55) completed...
Zika virus has rapidly spread through the World Health Organization's Region of Americas since being identified in Brazil early 2015. Transmitted primarily bite infected Aedes species mosquitoes, infection during pregnancy can cause spontaneous abortion and birth defects, including microcephaly (1,2). New York City (NYC) is home to a large number persons who travel frequently areas with active transmission, immigrants from these areas. In November 2015, NYC Department Mental Hygiene (DOHMH)...
Varicella is an illness characterized by a generalized, pruritic rash and transmitted through airborne, droplet, contact transmission.Although varicella causes mild-to-moderate symptoms in most persons, serious complications, including pneumonia death, can occur.In October 2022, the New York City (NYC) Department of Health Mental Hygiene (DOHMH) identified outbreak primarily involving persons who recently migrated from or Central South America lived NYC shelter residential facility;...
Both tuberculosis (TB) and COVID-19 can affect the respiratory system, early findings suggest co-occurrence of these infectious diseases result in elevated mortality. A retrospective cohort patients who were diagnosed with TB concurrently (within 120 days) between March 2020 June 2022 New York City (NYC) was identified. This compared a TB-alone during same period terms demographic information, clinical characteristics, Cox proportional hazards regression used to compare mortality patient...
OBJECTIVE: To calculate the per-session and annual direct program costs to implement directly observed therapy (DOT) for tuberculosis treatment conduct a cost attribution analysis under varying proportions of DOT utilization four types.DESIGN: Program data covering study period from September 2014 August 2015 in New York City (NYC) were used retrospective bottom-up micro-costing economic evaluation. For each type, potential savings estimated as averted by adopting uniform distribution...
In New York City, which was the epicenter of U.S. tuberculosis epidemic in 1990s, funding for control has been cut by more than 50%, and 2014 city reported its first increase cases after a decade continuous reductions.
Tuberculosis incidence in New York City (NYC) declined between 1992 and 2000 from 51.1 to 16.6 cases per 100,000 population. In January 2001, universal real-time genotyping of TB was implemented NYC. Isolates culture-confirmed tuberculosis 2001 2003 were genotyped using IS6110 spoligotype describe the extent factors associated with genotype clustering after declining incidence. Of 2408 (91.8%) case isolates, 873 (36.2%) had a pattern indistinguishable that another study period case, forming...
We studied two large Mycobacterium tuberculosis genotype clusters associated with recent outbreaks in homeless persons to determine factors these (TB) strains. Isolates from all culture-positive TB cases diagnosed 1 January 2001 31 December 2004 were genotyped. Patients whose isolates had identical restriction fragment length polymorphism patterns and spoligotypes considered clustered. Health department records reviewed reinterviews attempted for clustered cases. the Cs30 BEs75 strains...
In Brief Context: Treatment completion for tuberculosis (TB) is one of the essential components TB prevention and control. Delays in treatment incomplete can result increased transmission, development drug resistance, morbidity mortality. Understanding reasons poor outcomes may help improve control efforts. Objective: To identify those at highest risk determine among cases (January 2009-June 2010). Design: Retrospective analysis. Setting/Participants: New York City patients eligible to...
Factors influencing tuberculosis cluster growth are poorly understood. The authors examined clusters of two or more culture-confirmed Mycobacterium cases between January 1, 2001, and December 31, 2003, that had insertion sequence 6110 (IS6110) restriction fragment length polymorphism spoligotype patterns identical to those another study case. Genotypes first seen in New York, before during 1993 were considered historical; recent strains after 1993. the effect combined characteristics...
BACKGROUND: Electronic directly observed therapy (eDOT) has been proposed as an alternative to traditional in-person DOT (ipDOT) for monitoring TB treatment adherence. Information about the comparative performance and implementation of eDOT is limited. METHODS: The frequency challenges during DOT, challenge type, effect on medication observation were documented by method a crossover, noninferiority randomized controlled trial. A logistic mixed-effects model that adjusted study design was...
Background: Early in the 2022 mpox outbreak, vaccine doses and administrative capacity were limited. The US recommendation was to administer two of JYNNEOS(R) 4 weeks apart. However, because limited supply high demand, New York City (NYC) prioritized administration first reach a larger portion impacted population as quickly possible. We estimated cases averted compared strategies that 2-dose vaccination for smaller population. Methods: fit dynamic network transmission model incident reported...
To describe persons with suspected (did not meet the national tuberculosis [TB] surveillance case definition) and noncounted TB (met definition but transferred were counted by another jurisdiction) estimate costs incurred public health departments for managing them.We reviewed registry, medical records, budgets, bills, salaries, organizational charts, travel/activity logs from year 2000 at in New York City (NYC), three Texas (TX) counties (El Paso, Hidalgo, Webb), Massachusetts (MA). We also...
BACKGROUND: We evaluated patient safety within a randomized crossover trial comparing electronic directly observed therapy (eDOT) to in-person DOT (ipDOT) in persons undergoing TB treatment New York City, NY, USA. METHODS: Participant symptoms, symptom severity, and clinical management were documented. assessed adverse event reports (AERs) by method during the two-period crossover. Using Cox proportional-hazards mixed-effects models, we estimated adjusted hazard ratio (aHR) of participants...
<sec> <title>BACKGROUND</title> Since January 2013, the New York City (NYC) Health Department Tuberculosis (TB) Program has offered persons diagnosed with latent TB infection (LTBI) 3-month, once-weekly isoniazid and rifapentine (3HP) treatment regimen. Patients on this are monitored in-person under directly observed therapy (DOT). To address patient provider barriers to DOT, we piloted use of a videoconferencing software app remotely conduct synchronous DOT (video therapy; VDOT) for...