A5063282541- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Radiation Dose and Imaging
- Healthcare cost, quality, practices
- Effects of Radiation Exposure
- Homelessness and Social Issues
- Food Security and Health in Diverse Populations
- Healthcare Policy and Management
- Pharmaceutical studies and practices
- Emergency and Acute Care Studies
- HIV/AIDS Research and Interventions
- Radioactivity and Radon Measurements
- Radiopharmaceutical Chemistry and Applications
- Nuclear and radioactivity studies
- Chronic Disease Management Strategies
- HIV/AIDS drug development and treatment
- Adolescent Sexual and Reproductive Health
- Radioactive contamination and transfer
- COVID-19 and healthcare impacts
- Insect and Pesticide Research
- Risk and Safety Analysis
Centers for Disease Control and Prevention
2016-2025
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
2015-2025
Centers for Disease Control and Prevention
2019-2024
The Ohio State University
2023
Michigan Department of Health and Human Services
2023
California Department of Public Health
2013-2023
Arizona Department of Health Services
2023
University of Washington
2023
Public Health – Seattle & King County
2023
CDC Foundation
2002-2021
Section:ChooseTop of pageAbstract <<ContentsOverviewIntroductionGood Practices for Treati...Treatment MDR-TB, Numb...Drugs and Drug ClassesBuilding a Treatment Regi...Role Therapeutic ...Shorter-Course, Standardi...Role Surgery in MDR-TBTreatment Isoniazid-Re...Treatment MDR-TB Sp...Treatment Contacts Exp...Summary Key Difference...ReferencesCITING ARTICLES
Telehealth can facilitate access to care, reduce risk for transmission of SARS-CoV-2 (the virus that causes coronavirus disease 2019 ), conserve scarce medical supplies, and strain on health care capacity facilities while supporting continuity care.Health Resources Services Administration (HRSA)-funded centers* expanded telehealth † services during the COVID-19 pandemic (1).The Centers Medicare & Medicaid eliminated geographic restrictions enhanced reimbursement so services-enabled centers...
The objective of this study was to describe outcomes tuberculosis (TB) contact investigations, factors correlated with those outcomes, and current successes ways improve TB investigations. We abstracted clinic records a representative U.S. urban sample 1,080 pulmonary, sputum-smear( + ) patients reported CDC July 1996 through June 1997 the cohort their 6,225 close contacts. found median four contacts per patient. Fewer were identified for homeless patients. A visit patient's residence...
Abstract To describe factors associated with multidrug-resistant (MDR), including extensively-drug-resistant (XDR), tuberculosis (TB) in the United States, we abstracted inpatient, laboratory, and public health clinic records of a sample MDR TB patients reported to Centers for Disease Control Prevention from California, New York City, Texas during 2005–2007. At initial diagnosis, was detected 94% 130 XDR 80% 5 patients. Mutually exclusive resistance 4% XDR, 17% pre-XDR, 24% total first-line...
In 2020, the COVID-19 pandemic overburdened US health care system because of extended and unprecedented patient surges supply shortages in hospitals. We investigated extent to which several hospitals experienced emergency department (ED) intensive unit (ICU) overcrowding ventilator during pandemic.We analyzed Health Pulse data assess reported alerts when experiencing ED overcrowding, ICU from March 7, through April 30, 2021.Of 625 participating 29 states, 393 (63%) at least 1 hospital alert...
Randomized controlled trials have demonstrated that the newest latent tuberculosis (LTBI) regimen, 12 weekly doses of directly observed isoniazid and rifapentine (3HP), is as efficacious 9 months isoniazid, with a greater completion rate (82% vs 69%); however, 3HP has not been assessed in routine healthcare settings. Observational cohort LTBI patients receiving through 16 US programs was used to assess treatment completion, adverse drug reactions, factors associated discontinuation. Of 3288...
We estimated long-term tuberculosis (TB) trends in the US population and assessed prospects for TB elimination. used a detailed simulation model allowing changes transmission, immigration, other risk determinants. Five hypothetical scenarios were evaluated from 2017 to 2100: 1) maintain current prevention treatment activities (base case); 2) provision of latent infection testing new legal immigrants; 3) increased uptake screening among high-risk populations, including 3-month...
A large randomized controlled trial recently showed that for treating latent tuberculous infection (LTBI) in persons at high risk of progression to tuberculosis (TB) disease, a 12-dose regimen weekly rifapentine plus isoniazid (3HP) administered as directly observed treatment (DOT) can be effective 9 months daily self-administered (9H).
Elevated tuberculosis (TB) incidence rates have recently been reported for racial/ethnic minority populations in the United States. Tracking such disparities is important assessing progress toward national health equity goals and implementing change.
In the United States, older adults have elevated prevalence of latent tuberculosis infection (LTBI) and incidence (TB). To estimate health benefits cost-effectiveness LTBI testing treatment among Medicare-eligible population. Model-based analysis. Nationally representative surveys published evidence. persons aged 65 years or with at least 1 15 factors associated TB risk, as identified by guidelines from U.S. Preventive Services Task Force (USPSTF) other organizations. Lifetime. Societal....
Individuals surviving TB disease may experience chronic sequelae that reduce survival and quality-of-life. These post-TB sequalae are not generally considered in estimates of the health impact disease. To estimate TB-attributable reductions life expectancy quality-adjusted for individuals developing United States, including sequelae. We extracted national surveillance data on diagnosed with during 2015-2019, demographics, vital status at diagnosis, treatment duration, outcome, co-prevalent...
Outbreak investigation is an essential component of tuberculosis (TB) control in the United States, but its epidemiologic impact and cost-effectiveness have not been quantified. We modeled outbreak activities States during 2023-2032 estimated corresponding impact, economic costs (in 2022 US$), incremental ratios from healthcare system perspective (cost per additional quality-adjusted life-year gained). projected that investigations would result 1,030,000 (95% uncertainty interval [UI]...
Tuberculosis (TB) notifications and deaths in the United States fluctuated substantially during COVID-19 pandemic. We analyzed multiple data sources to understand factors contributing these changes estimated future TB trends. identified four mechanisms potentially observed trends 2020-2023: immigration, respiratory contact rates, rates of accurate diagnosis treatment initiation, mortality for persons experiencing disease. employed a Bayesian approach synthesize evidence on how changed...
Background: Risk of tuberculosis (TB) declines over time since Mycobacterium infection, but progression to clinical disease is still possible decades later. In the United States, most TB cases result from latent infection acquired 2 years ago. Methods: We synthesized evidence on natural history and incidence trends using a transmission-dynamic model. For 2020 US population, we estimated average annual, cumulative, remaining lifetime risks TB, by nativity age. Results: newly infected adult...
Targeted testing and treatment (TTT) for latent tuberculosis (TB) infection (LTBI) is a recommended strategy to accelerate TB reductions further elimination in the United States. Evidence on cost-effectiveness of TTT key populations can help advance this goal.We used model transmission estimate numbers individuals who could be tested by interferon-γ release assay treated LTBI with 3 months self-administered rifapentine isoniazid (3HP) under various scenarios. Specifically, we considered...
Objectives. To assess costs of video and traditional in-person directly observed therapy (DOT) for tuberculosis (TB) treatment to health departments patients in New York City, Rhode Island, San Francisco, California.Methods. We collected department DOT (VDOT; live recorded), (field- clinic-based). Time-motion surveys estimated provider time cost. A separate survey patient costs. used a regression model estimate cost by type.Results. Between August 2017 June 2018, 343 sessions were captured...
The maxillary sinus is an uncommon site for mucoceles within the paranasal sinuses. In this study nine patients with are presented. Six of these were treated by open approaches, and three endoscopic drainage alone. For uncomplicated mucoceles, appears to be a reasonable approach, whereas more complicated cases extending outside sinus, approaches may required.