Alexey Clara

ORCID: 0000-0003-3779-3449
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About
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Research Areas
  • Respiratory viral infections research
  • Viral Infections and Outbreaks Research
  • Influenza Virus Research Studies
  • COVID-19 epidemiological studies
  • Emergency and Acute Care Studies
  • Pneumonia and Respiratory Infections
  • Data-Driven Disease Surveillance
  • Vaccine Coverage and Hesitancy
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Viral gastroenteritis research and epidemiology
  • Malaria Research and Control
  • Disaster Response and Management
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Vibrio bacteria research studies
  • Global Maternal and Child Health
  • Animal Disease Management and Epidemiology
  • COVID-19 Pandemic Impacts
  • Mental Health Treatment and Access
  • Patient Satisfaction in Healthcare
  • COVID-19 and healthcare impacts
  • Food Security and Health in Diverse Populations
  • COVID-19 Digital Contact Tracing
  • Telemedicine and Telehealth Implementation
  • Sepsis Diagnosis and Treatment

Centers for Disease Control and Prevention
2014-2024

World Health Organization
2022

World Health Organization - Pakistan
2022

National Center for Immunization and Respiratory Diseases
2018-2021

CDC Foundation
2021

General Department of Preventive Medicine
2018

National Institute Of Hygiene And Epidemiology
2018

Program for Appropriate Technology in Health
2018

Institut Pasteur in Ho Chi Minh City
2018

University of El Salvador
2014-2016

Introduction Literature on influenza focuses A, despite B having a large public health impact. The Global Influenza Study aims to collect information global epidemiology and burden of disease since 2000. Methods Twenty‐six countries in the Southern ( n = 5) Northern 7) hemispheres intertropical belt 14) provided virological epidemiological data. We calculated proportion cases due type Victoria Yamagata lineages each country season; tested correlation between maximum weekly influenza‐like...

10.1111/irv.12319 article EN cc-by-nc Influenza and Other Respiratory Viruses 2015-08-01

Telehealth can facilitate access to care, reduce risk for transmission of SARS-CoV-2 (the virus that causes coronavirus disease 2019 ), conserve scarce medical supplies, and strain on health care capacity facilities while supporting continuity care.Health Resources Services Administration (HRSA)-funded centers* expanded telehealth † services during the COVID-19 pandemic (1).The Centers Medicare & Medicaid eliminated geographic restrictions enhanced reimbursement so services-enabled centers...

10.15585/mmwr.mm7007a3 article EN MMWR Morbidity and Mortality Weekly Report 2021-02-18

Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within strata using surveillance data from twenty-nine countries during 1999-2014 (N=358,796 cases). For each virus, we calculated a Relative Illness Ratio (defined as ratio percentage cases in an group to country population same group) for young children (0-4 years), older (5-17 adults (18-39 (40-64 elderly (65+ years). used...

10.1186/s12879-018-3181-y article EN cc-by BMC Infectious Diseases 2018-06-08

Introduction Determining the optimal time to vaccinate is important for influenza vaccination programmes. Here, we assessed temporal characteristics of epidemics in Northern and Southern hemispheres tropics, discuss their implications Methods This was a retrospective analysis surveillance data between 2000 2014 from Global Influenza B Study database. The seasonal peak defined as week with most reported cases (overall, A, B) season. duration activity using maximum proportion during three...

10.1371/journal.pone.0152310 article EN public-domain PLoS ONE 2016-03-31

Background The role of meteorological factors on influenza transmission in the tropics is less defined than temperate regions. We assessed association between activity and temperature, specific humidity rainfall 6 study areas that included 11 departments or provinces within 3 tropical Central American countries: Guatemala, El Salvador Panama. Method/Findings Logistic regression was used to model weekly proportion laboratory-confirmed positive samples during 2008 2013 (excluding pandemic year...

10.1371/journal.pone.0100659 article EN cc-by PLoS ONE 2014-06-23

Background Influenza‐associated illness results in increased morbidity and mortality the Americas. These effects can be mitigated with an appropriately chosen timed influenza vaccination campaign. To provide guidance choosing most suitable vaccine formulation timing of administration, it is necessary to understand seasonal epidemics. Objectives Our main objective was determine whether occurs patterns American tropics when these occurred. Methods Publicly available, monthly data from Pan...

10.1111/irv.12371 article EN cc-by Influenza and Other Respiratory Viruses 2015-12-24

Introduction Existing risk assessment tools to identify children at of hospitalised pneumonia-related mortality have shown suboptimal discriminatory value during external validation. Our objective was derive and validate a novel tool aged 2–59 months across various settings. Methods We used primary, baseline, patient-level data from 11 studies, including evaluated for pneumonia in 20 low-income middle-income countries. Patients with complete were included logistic regression model assess the...

10.1136/bmjgh-2021-008143 article EN cc-by-nc BMJ Global Health 2022-04-01

ObjectivesWe determined the pulse oximetry benefit in pediatric pneumonia mortality risk stratification and chest-indrawing in-hospital factors.MethodsWe report characteristics pneumonia-related of children aged 2-59 months who were included Pneumonia Research Partnership to Assess WHO Recommendations dataset. We developed multivariable logistic regression models identify factors.ResultsAmong 285,839 children, 164,244 (57.5%) from hospital-based studies included. case fatality (CFR) without...

10.1016/j.ijid.2023.02.005 article EN cc-by International Journal of Infectious Diseases 2023-02-16

Clinical observations and some studies suggest that dengue virus infection is more severe among children with better nutritional status. We examined the status of in El Salvador its relationship between this severity infection. Z-scores for weight-for-age, height-for-age, body mass index (BMI)-for-age fever (66), hemorrhagic (62), healthy controls (74) were compared. There no differences weight-for-age or BMI-for-age three groups. Children had a greater height-for-age than but significant...

10.4269/ajtmh.2010.09-0365 article EN American Journal of Tropical Medicine and Hygiene 2010-02-01

Abstract Surveillance and outbreak reporting systems in Vietnam required improvements to function effectively as early warning response systems. Accordingly, the Ministry of Health Vietnam, collaboration with US Centers for Disease Control Prevention, launched a pilot project 2016 focusing on community hospital event–based surveillance. The was implemented 4 Vietnam's 63 provinces. demonstrated that event-based surveillance resulted detection outbreaks, improved between healthcare facilities...

10.3201/eid2409.171851 article EN cc-by Emerging infectious diseases 2018-09-01

Abstract Background In view of ongoing pandemic threats such as the recent human cases novel avian influenza A(H7N9) in China, it is important that all countries continue their preparedness efforts. Since 2006, Central American have received donor funding and technical assistance from U.S. Centers for Disease Control Prevention (CDC) to build improve capacity surveillance preparedness. Our objective was measure changes this region, explore factors associated with these changes, using...

10.1186/1472-6963-14-209 article EN cc-by BMC Health Services Research 2014-05-09

Community-based surveillance can be an important component of early warning systems. In 2016, the Côte d'Ivoire Ministry Health launched a community-based project in 3 districts along Guinea border. Community health workers were trained detection and immediate reporting diseases events using text-messaging platform. December 2017, data from before after implementation analyzed intervention control districts. A total 3,734 signals priority 4,918 unusual reported, which 420 investigated as...

10.1089/hs.2019.0062 article EN Health Security 2020-01-01

Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was externally validate three such scores. We applied the Respiratory Index Severity in Children (RISC) for HIV-negative children, RISC-Malawi, and Pneumonia Etiology Research Child Health (PERCH) REsearch Partnerships Assess WHO REcommendations (PREPARE) data set. The PREPARE set includes pooled from 41 studies on pediatric pneumonia across world. calculated...

10.7189/jogh.11.04062 article EN cc-by Journal of Global Health 2021-10-09

Community event-based surveillance aims to enhance the early detection of emerging public health threats and thus build security. The Ministry Health Vietnam launched a community pilot program in 6 provinces improve warning functions existing system. An evaluation took place 2017 2018. Data from this were analyzed determine which factors associated with increased reporting. Results show that number small, local events detected reported through surveillance, supporting notion it would also...

10.1089/hs.2018.0066 article EN Health Security 2018-11-27

Abstract Data needed to guide influenza vaccine policies are lacking in tropical countries. We multiplied the number of severe acute respiratory infections by proportion testing positive for influenza. There were ≈6,699 hospitalizations and 803 deaths Costa Rica during 2009–2012, supporting continuation a national program.

10.3201/eid2005.131775 article EN cc-by Emerging infectious diseases 2014-04-22

Ghana Health Service (GHS) has strengthened community-based surveillance (CBS) to facilitate early detection and rapid reporting of health events all origins. Since June 2017, GHS employed an event-based approach at the community level in a phased manner. CBS coverage broadened from 2 30 districts across Ghana. Through this effort, capacity was built administrative levels these detect, report, triage, verify signals, perform risk assessment investigate events. Data were collected analyzed...

10.1371/journal.pone.0237320 article EN public-domain PLoS ONE 2020-08-11

Background and objectivesAlthough acute respiratory illness (ARI) is a leading cause of hospitalization among young children, few data are available about cost in middle-income countries. We estimated direct indirect costs associated with severe ARI resulting children aged <10 years El Salvador Panama through the societal perspective.MethodsDuring 2012 2013, we surveyed caregivers hospitalized their medical (i.e., outpatient consultation, medications, hospital fees), non-medical...

10.1016/j.jinf.2019.05.021 article EN cc-by-nc-nd Journal of Infection 2019-05-31

Abstract Surveillance and outbreak reporting systems in Vietnam required improvements to function effectively as early warning response systems. Accordingly, the Ministry of Health Vietnam, collaboration with US Centers for Disease Control Prevention, launched a pilot project 2016 focusing on community hospital event–based surveillance. The was implemented 4 Vietnam’s 63 provinces. demonstrated that event-based surveillance resulted detection outbreaks, improved between healthcare facilities...

10.3201/eid2409 article EN cc-by Emerging infectious diseases 2018-07-30

We estimate the proportion of patients hospitalized for suspected dengue that tested positive influenza virus in El Salvador during 2012 season. specimens from 321 patients: 198 with SARI and 123 dengue. Among 121 (two co-infected excluded) patients, 28% 19% influenza; among 35 respiratory symptoms, 14% were 39% influenza. One percent presented co-infection between Clinicians should consider diagnosis

10.1371/journal.pone.0140890 article EN public-domain PLoS ONE 2015-10-20
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