A5087543710- Respiratory viral infections research
- Influenza Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Asthma and respiratory diseases
- Virology and Viral Diseases
- Proteoglycans and glycosaminoglycans research
- Glycosylation and Glycoproteins Research
- Acute Lymphoblastic Leukemia research
- Animal Virus Infections Studies
- Vaccine Coverage and Hesitancy
- Respiratory and Cough-Related Research
- Immunodeficiency and Autoimmune Disorders
- Contact Dermatitis and Allergies
- Multi-Criteria Decision Making
- Inhalation and Respiratory Drug Delivery
- COVID-19 and healthcare impacts
- Allergic Rhinitis and Sensitization
- Neuroblastoma Research and Treatments
- Public Health and Environmental Issues
- Skin and Cellular Biology Research
- Plant Virus Research Studies
- Hematopoietic Stem Cell Transplantation
- Fibroblast Growth Factor Research
- Trypanosoma species research and implications
Instituto de Salud Pública de Chile
2010-2023
Hospital Militar de Santiago
2017
Sociedad Española de Nefrología
2017
Ministry of Health
2016
Global Viral
2011
Pontificia Universidad Católica de Chile
1991-1996
To test our previous observation that methotrexate reduces corticosteroid requirements of patients with severe asthma, we studied 14 corticosteroid-dependent bronchial asthma in a 24-week randomized double-blind crossover trial comparing low dosage (15 mg per week) placebo. At base line the mean prednisone was 173.5 week (range, 70 to 420). On average, 36.5 percent less required when received than they placebo (P = 0.01). Measurement forced vital capacity and expiratory volume one second...
Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within strata using surveillance data from twenty-nine countries during 1999-2014 (N=358,796 cases). For each virus, we calculated a Relative Illness Ratio (defined as ratio percentage cases in an group to country population same group) for young children (0-4 years), older (5-17 adults (18-39 (40-64 elderly (65+ years). used...
Highlights Here we present the first human case of Influenza A H5N1 infection in Chile, and fifth worldwide 2023.The patient is a 53-year-old man who lives north region near seashore.The Chilean sample was subtyped clade 2.3.4.4b.
Introduction Determining the optimal time to vaccinate is important for influenza vaccination programmes. Here, we assessed temporal characteristics of epidemics in Northern and Southern hemispheres tropics, discuss their implications Methods This was a retrospective analysis surveillance data between 2000 2014 from Global Influenza B Study database. The seasonal peak defined as week with most reported cases (overall, A, B) season. duration activity using maximum proportion during three...
The current pandemic caused by the new coronavirus is a worldwide public health concern. To aboard this emergency, and like never before, scientific groups around world have been working in fast coordinated way to get maximum of information about virus when it has almost 3 months since first cases were detected Wuhan province China. complete genome sequences 450 isolates are available, studies similarities differences among them with close related viruses that similar epidemics century. In...
The pandemic caused by the new coronavirus SARS-CoV-2 is a worldwide public health concern. First confined in China, and then disseminated widely across Europe America, has impacted moved scientific community around world to working fast coordinated way collect all possible information about this virus generate strategies protocols try stop infection. During March 2020, more than 16,000 full viral genomes have been shared databases, that allow construction of genetic landscapes for tracking...
In 2013, the Pan American Health Organization established a multi-site, multi-country network to evaluate influenza vaccine effectiveness (VE). We pooled data from five consecutive seasons in countries conduct an analysis of southern hemisphere VE against laboratory-confirmed hospitalizations young children and older adults.We used test-negative design estimate hospitalized (aged 6─24 months) adults ≥60 years) Argentina, Brazil, Chile, Colombia, Paraguay. Following country-specific...
Proteoglycans (PGs) are abundant components of the extracellular matrices (ECM) skeletal muscle. We have previously found that synthesis muscle PGs present at ECM increase after denervation. The experiments reported here were undertaken to identify which PG(s) denervation rat leg muscles. Incorporation radioactive sulfate demonstrated presence a chondroitin/dermatan PG 70-90 kDa in ECM, increased has core protein 39-45 treatment with chondroitinase ABC. Antibodies against decorin,...
Human rhinovirus (HRV) is an emerging viral pathogen. To characterize a group of patients admitted due to infection by this agent in general hospital Chile. Cases were identified RT-PCR for 1 year through active surveillance with severe respiratory illness. Diagnosis was not available during hospitalization. Thirty-two cases identified, 90% ≥60 years old or had co-morbid conditions. rhinovirus-related admissions represented 23.7% hospitalization acute infections among adults and ranked...
Abstract Diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS‐COV‐2) cases is based on the count real‐time reverse transcription‐plymerase chain reaction (RT‐PCR) positive people. Viral load by RT‐PCR has been suggested as a biomarker SARS‐CoV‐2 infection. However, association viral and severity disease not yet resolved. Nasopharyngeal samples from 458 patients were tested for diagnosis. Relative quantitation was made comparative threshold cycle (ΔΔ C t ) formula between ORF1ab...
Background. Strategies for accelerated control of rubella and congenital syndrome (CRS) in Chile included mass vaccination women childbearing age 1999 but did not include adult men. Methods. We reviewed data from Chile's integrated surveillance system measles, rubella, CRS 2004 through 2009 describe the epidemiology outbreaks implementation measures 2005 2007 following women. Population estimates census were used to calculate incidence rates. The distribution cases during was compared with...
O transporte rodoviário é responsável por 61,1% do de mercadorias no Brasil, com uma rede 1.721.342 km. A ANTT (Agência Nacional Transportes Terrestres) regula o terrestre bens, incluindo produtos perigosos, conforme a legislação. Setores como mineração, petróleo, gás, indústria bélica e segurança pública utilizam explosivos, classificados classe 1 perigosos pela ONU (Organização das Nações Unidas). Uma revisão da literatura identificou falta pesquisas específicas sobre explosivos. Esta...
Background: Except for influenza pandemics, different observational studies have failed to demonstrate differences in mortality between various etiologies adult patients hospitalized respiratory infections.
Acute glomerulonephritis with hemodialysis requirement secondary to influenza A H1N1pdm09 infection. Report of two casesAcute renal failure (ARF) requiring is not common among patients affected by influenza.We report unvaccinated adult smoking habit, which were admitted severe that evolved shock and required mechanical ventilation.Both developed progressive oliguria/anuria, associated urinary inflammatory sediment proteinuria, microhematuria in one case also hypocomplementemia, suggesting...
Genetic characterization of the virus causing H1N1 infl uenza pandemic in Chile.Analysis fi rst detected cases Background: Following announcement Infl A(H1N1) by World Health Organization April 2009, a surveillance program was carried out Chile to detect introduction country and monitor its propagation impact.Aim: To describe onset outbreak genetic Chile.Material Methods: Analysis 18 clinical samples coming from suspicious patients, received National Reference Laboratory.RNA reverse...
La rubeola es una enfermedad benigna que se transforma en un problema de salud publica cuando afecta a mujeres embarazadas, pudiendo causar graves problemas al feto si llega desarrollar el Sindrome Rubeola Congenita (SRC). Para evitar esto, las nuestro pais entre 10 y 29 anos, fueron protegidas la campana vacunacion del ano 1999 con 99% cobertura; momento cual veia enfrentado brote rubeola. vacuna trivirica introdujo Chile 1990; posterior a ello, la tendencia de fue al...
La rubéola es una enfermedad benigna que se transforma en un problema de salud pública cuando afecta a mujeres embarazadas, pudiendo causar graves problemas al feto si llega desarrollar el Síndrome Rubéola Congénita (SRC). Para evitar esto, las nuestro país entre 10 y 29 años, fueron protegidas la campaña vacunación del año 1999 con 99% cobertura; momento cual veía enfrentado brote rubéola.La vacuna trivírica introdujo Chile 1990; posterior ello, tendencia fue descenso hasta los años 1997-...