A5002263361- Genomics and Phylogenetic Studies
- Aquaculture disease management and microbiota
- Microbial Community Ecology and Physiology
- Gut microbiota and health
- Methane Hydrates and Related Phenomena
- Insect and Arachnid Ecology and Behavior
- Protist diversity and phylogeny
- Cancer-related molecular mechanisms research
- Antimicrobial Resistance in Staphylococcus
- Parasitic Infections and Diagnostics
- Sphingolipid Metabolism and Signaling
- Carbohydrate Chemistry and Synthesis
- Forest Insect Ecology and Management
- Biochemical and Structural Characterization
- Clostridium difficile and Clostridium perfringens research
- Plant Parasitism and Resistance
- Cocoa and Sweet Potato Agronomy
- Plant and animal studies
- Fungal Infections and Studies
- Connective tissue disorders research
- Insect-Plant Interactions and Control
- Insect Utilization and Effects
- Lysosomal Storage Disorders Research
- Amoebic Infections and Treatments
- Mollusks and Parasites Studies
Instituto de Salud Pública de Chile
2022-2023
Clínica Alemana
2019-2022
Universidad del Desarrollo
2019-2022
Universidad Estatal de Bolívar
2022
Millennium Initiative for Collaborative Research on Bacterial Resistance
2019
Universidad Mayor
2014-2018
National Institute of Quality
2017
University of Talca
2014
Highlights Here we present the first human case of Influenza A H5N1 infection in Chile, and fifth worldwide 2023.The patient is a 53-year-old man who lives north region near seashore.The Chilean sample was subtyped clade 2.3.4.4b.
Long non-coding RNAs (lncRNAs) have been defined as transcripts longer than 200 nucleotides, which lack significant protein coding potential and possess critical roles in diverse cellular processes. recently functionally characterized plant stress-response mechanisms. In the present study, we perform a comprehensive identification of lncRNAs response to combined stress induced by salinity excess boron Lluteño maize, tolerant maize landrace from Atacama Desert, Chile. We use deep RNA...
Shigella sonnei is a globally important diarrhoeal pathogen tracked through the surveillance network PulseNet Latin America and Caribbean (PNLA&C), which participates in International. PNLA&C laboratories use common molecular techniques to track pathogens causing foodborne illness. We aimed demonstrate possibility advantages of transitioning whole genome sequencing (WGS) for within existing networks across continent where S. endemic.We applied WGS representative archive isolates (n = 323)...
Edible insects can represent an alternative to obtain high-quality proteins with positive biological properties for human consumption. Cricket flour (Gryllus assimilis) was used cricket protein concentrate (CPC) using pHs (10.0 and 12.0) of extraction (3.0, 4.0, 5.0, 6.0) isoelectric precipitation (pI). Protein content, water oil absorption capacity, solubility, antioxidant, anti-inflammatory activities were determined. In addition, the profile characterized by electrophoresis in vitro CPC...
We report here the draft genome sequence of a lethal pathogen farmed salmonids, Piscirickettsia salmonis strain AUSTRAL-005. This virulent was isolated in 2008 from Oncorhynchus mykiss farms, and multiple genes involved pathogenicity, environmental adaptation, metabolic pathways were identified.
ABSTRACT Cáhuil Lagoon in central Chile harbors distinct microbial communities various solar salterns that are arranged as interconnected ponds with increasing salt concentrations. Here, we report the metagenome of 3.0- to 0.2-µm fraction community present a crystallizer pond 34% salinity.
Infections caused by multidrug-resistant organisms (MDRO) lead to considerable morbidity and mortality. The elderly population residing in nursing homes are a major reservoir of MDRO. Our objective was characterize the fecal microbiome 82 subjects from 23 compare their resistome that healthy young persons. Comparisons composition between who acquired MDRO or not were analyzed specific disruption indices (MDI) associated with acquisition. An approach based on both 16S rRNA amplicon whole...
In recent years, several studies have evidenced the importance of microbiome to host physiology as metabolism regulator, along with its potential role in triggering various diseases. this study, we analyzed gut microbiota hypercholesterolemic (cases) and normocholesterolemic (controls) individuals identify characteristic microbial signature for each condition.Stool samples were obtained from 57 adult volunteers (27 30 controls). The taxonomic profiling communities was performed using...
Poplars are frequently attacked by aphids. The differential susceptibility of poplar hybrids to the aphid Chaitophorus leucomelas Koch (Sternorrhyncha: Aphididae) has been described, but mechanism underlying this pattern is unknown. This work tested hypothesis that resistance associated with presence volatiles and secondary plant compounds affect host selection feeding behavior. was studying choice behavior C. on two contrasting susceptibilities ([Populus trichocarpa Torrey & Gray × Populus...
Here, we report the first draft genome sequence of Lactobacillus kunkeei strain MP2, isolated from a Chilean honeybee gut. The sequenced has total size 1.58 Mb distributed into 44 contigs and 1,356 protein-coding sequences.
Here, we report the genome sequence and evidence for transcriptional activity of a virus-like element in native Chilean berry tree Aristotelia chilensis. We propose to name endogenous as chilensis Virus 1 (AcV1). High-throughput sequencing this uncovered an viral element, with size 7122 bp, corresponding complete AcV1. Its contains three open reading frames (ORFs): ORFs 2 shares 66%-73% amino acid similarity members Caulimoviridae virus family, especially Petunia vein clearing (PVCV),...
Abstract Background The MRSA Chilean-Cordobes (ChC) clone belongs to the clonal complex 5 (CC5) and typically carries SCCmec I. ChC predominated widely throughout several countries of Latin America (LA), but during mid-2000s a CA-MRSA CC8 LA variant (USA300-LV) quickly replaced in Colombia Ecuador. Most notably, this replacement was not observed Peru or Chile. Here, we aimed understand phylogenomic relatedness CC5 obtained from different LA. Methods We sequenced analyzed genomes 115 isolates...
The acid β-glucocerebrosidase (GCase) enzyme cleaves glucosylceramide into glucose and ceramide. Loss of function variants in the gene encoding for GCase can lead to Gaucher disease Parkinson's disease. Therapeutic strategies aimed at increasing activity by targeting a modulating factor are attractive poorly explored. To identify genetic modifiers, we measured hepatic 27 inbred mouse strains. A genome-wide association study (GWAS) using as trait identified several candidate modifier genes,...
Bacillus amyloliquefaciens strain 629 is an endophyte isolated from Theobroma cacao L. Here, we report the draft genome sequence (3.9 Mb) of B. containing 16 contigs (3,903,367 bp), 3,912 coding sequences, and average 46.5% G+C content.
Marfan Syndrome (MFS) is an autosomal dominant condition caused by variants in the fibrillin-1 (FBN1) gene. Cardinal features of MFS include ectopia lentis (EL), musculoskeletal and aortic root aneurysm dissection. Although dissection ascending aorta main cause mortality MFS, clinical course differs considerably age onset severity, even among individuals who share same causative variant, suggesting existence additional genetic that modify severity cardiovascular phenotype MFS. We recruited...
Abstract Background CPT is a last-generation cephalosporin active against MRSA due to its affinity for PBP2a. CPT-resistance (CPT-R) well-described, with mutations in the transpeptidase domain of PBP2a associated high-level resistance. The accumulation changes non-penicillin-binding has been linked elevations minimal inhibitory concentration (MIC) levels around 2-4ug/mL. PBP4 and PBP2 have also implicated as potentially relevant mecA-independent mechanisms CPT-R. We recently reported high...