A5086251028- Telomeres, Telomerase, and Senescence
- Genetics, Aging, and Longevity in Model Organisms
- Microbial infections and disease research
- Pluripotent Stem Cells Research
- Virus-based gene therapy research
- Spaceflight effects on biology
- Toxoplasma gondii Research Studies
- RNA Interference and Gene Delivery
- DNA Repair Mechanisms
- Aquaculture disease management and microbiota
- Global Health Care Issues
- Immunotherapy and Immune Responses
- Plant Virus Research Studies
- Herpesvirus Infections and Treatments
- Insurance, Mortality, Demography, Risk Management
- Birth, Development, and Health
- Bacteriophages and microbial interactions
- Mesenchymal stem cell research
- Biomedical Ethics and Regulation
- Viral gastroenteritis research and epidemiology
- Polyomavirus and related diseases
- Nutrition, Genetics, and Disease
- Animal Virus Infections Studies
- Hemoglobin structure and function
- Pancreatic function and diabetes
University of California, San Francisco
2005-2021
University of Illinois Chicago
2002-2017
University of California System
1989-2011
Entomological Society of America
2007
Gerontological Society of America
2007
Brooklyn College
2007
Washington State University
2007
Marine Biological Laboratory
2007
New York University
2007
University of Oklahoma Health Sciences Center
2005
Estimates of future life expectancy strongly influence public policy on age-based entitlement programs such as Social Security and Medicare. Although recent estimates how long Americans will live in this century have predicted an increase, the authors believe that current trends obesity United States may end slow but steady increase has taken place past 2 centuries. In 3 decades, rise at birth decelerated context historical trends. Recent exploration by experts, including mathematical...
Recent volunteer and controlled epidemiologic field studies have provided evidence which firmly associates the agent first recovered by Eaton in 1944 with lower respiratory tract illness of man.1-3 A serologic response to occurs approximately 90 per cent pneumonia illnesses cold agglutinins develop during convalescence as well a significant but variable proportion agglutinin-negative pneumonias.2 4 The development other forms disease following administration tissue culture-grown volunteers...
The doubling potential of several hundred clones derived from WI-38 and WI-26 cell cultures has been determined. Clones were isolated at various population levels (PDLs) during the finite in vitro life-span mass (uncloned) cultures. In all cases, there was a large variation (or life-span) among single culture. When which had undergone eight or nine doublings, only about 50% capable more than doublings. This percentage further reduced when higher PDLs. Mass appear to be composed two...
Forecasts of life expectancy are an important component public policy that influence age-based entitlement programs such as Social Security and Medicare. Although the Administration recently raised its estimates how long Americans going to live in 21st century, current trends obesity United States suggest these may not be accurate. From our analysis effect on longevity, we conclude steady rise during past two centuries soon come end.
Of all the conflicting views on causes of biologic aging, there is little disagreement with axiom that, after reaching sexual maturity, individual members a species accumulate physiologic decrements that lead to an increase in their likelihood dying. In fact, for man actuarial data, first analyzed by English actuary Gompertz 1825, reveal force mortality doubles every seven years beyond age 30 — is, rate and probability dying are exponential increasing age. The variety human functions,...
Senescent human diploid cell cultures (WI-38 and WI-26) were studied during Phase III for survival time, ability to synthesize DNA, nuclear morphology. Periodic transfers made a 6-month period of showed that maintained with only slight variations in number. No sign spontaneous acquisition infinite proliferative potential was observed. The increase the number multinucleated cells found observation progressive changes occur III. A certain proportion incorporate tritiated thymidine throughout...
The light intensity-fusion frequency relationship of the goldfish electroretinogram follows Ferry-Porter law except at higher intensities. Maximum fusion increases with temperature thus contradicting results studies elsewhere on behavioral responses in sunfish.