A5062622249- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Obesity and Health Practices
- Genetic Associations and Epidemiology
- Genetic and phenotypic traits in livestock
- Eating Disorders and Behaviors
- Genetic Mapping and Diversity in Plants and Animals
- Genetics, Aging, and Longevity in Model Organisms
- Dietary Effects on Health
- Birth, Development, and Health
- Gene expression and cancer classification
- Meta-analysis and systematic reviews
- Body Composition Measurement Techniques
- Nutrition and Health in Aging
- Pharmacology and Obesity Treatment
- Regulation of Appetite and Obesity
- Statistical Methods in Clinical Trials
- Health Systems, Economic Evaluations, Quality of Life
- HIV Research and Treatment
- Nutrition, Genetics, and Disease
- Food Security and Health in Diverse Populations
- Biochemical Analysis and Sensing Techniques
- Advanced Causal Inference Techniques
Indiana University Bloomington
2017-2025
University of Alabama at Birmingham
2011-2024
University of Maryland, Baltimore
2024
Clemson University
2007-2023
Soleno Therapeutics (United States)
2023
Indiana University
2019-2023
General Mills (United States)
2023
Cargill (United States)
2023
National Cattlemen's Beef Association
2023
Medpace (United States)
2011-2023
Public health officials and organizations have disseminated messages regarding the dangers of obesity, but these not produced desired effect.To estimate expected number years life lost (YLL) due to overweight obesity across span an adult.Data from (1) US Life Tables (1999); (2) Third National Health Nutrition Examination Survey (NHANES III; 1988-1994); (3) First Epidemiologic Follow-up Study I II; 1971-1992) NHANES II Mortality (1976-1992) were used derive YLL estimates for adults aged 18 85...
Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse species; however, its effect on resistance to illness mortality primates has not been clearly established. We report findings of a 20-year longitudinal adult-onset CR study rhesus monkeys aimed at filling this critical gap research. In population macaques maintained the Wisconsin National Primate Research Center, moderate lowered incidence aging-related deaths. At time point reported, 50% control...
BESITY IS A SERIOUS MEDIcal problem, increasing in prevalence, affecting millions, 1 and of great interest to the public.To articulate burden obesity, investigators have used indicators such as 1,2 economic cost, 3 association with risk factors diseases. 4However, there is little published scientific information on number annual obesityattributable deaths United States.Mass media, 5-8 scholarly journals, 9-11 pharmaceutical handouts 12 cited 300 000 per year States being attributable a that...
Estimates of future life expectancy strongly influence public policy on age-based entitlement programs such as Social Security and Medicare. Although recent estimates how long Americans will live in this century have predicted an increase, the authors believe that current trends obesity United States may end slow but steady increase has taken place past 2 centuries. In 3 decades, rise at birth decelerated context historical trends. Recent exploration by experts, including mathematical...
OBJECTIVES: This study sought to test the relationships between relative body weight and clinical depression, suicide ideation, attempts in an adult US general population sample. METHODS: Respondents were 40,086 African American White participants interviewed a national survey. Outcome measures past-year major diagnosed according Diagnostic Statistical Manual of Mental Disorders, Fourth Edition. The primary predictor was weight, treated both continuously (i.e., mass index [BMI])...
Obesity adversely affects cardiac function, increases the risk factors for coronary heart disease, and is an independent factor cardiovascular disease. The of developing disease directly related to concomitant burden obesity-related factors. Modest weight loss can improve diastolic function affect entire cluster simultaneously. This statement from American Heart Association Council on Nutrition, Physical Activity, Metabolism reviews relationship between obesity system, evaluates effect...
SummaryWe analyzed the European genetic contribution to 10 populations of African descent in United States (Maywood, Illinois; Detroit; New York; Philadelphia; Pittsburgh; Baltimore; Charleston, South Carolina; Orleans; and Houston) Jamaica, using nine autosomal DNA markers. These markers either are population-specific or show frequency differences >45% between parental thus especially informative for admixture. ancestry ranged from 6.8% (Jamaica) 22.5% (New Orleans). The unique utility...
Abstract Caloric restriction (CR) without malnutrition extends lifespan and delays the onset of age-related disorders in most species but its impact nonhuman primates has been controversial. In late 1980s two parallel studies were initiated to determine effect CR rhesus monkeys. The University Wisconsin study reported a significant positive on survival, National Institute Aging detected no survival effect. Here we present direct comparison longitudinal data from both including bodyweight,...
Abstract Objective : This study was designed to assess physicians’ attitudes toward obese patients and the causes treatment of obesity. Research Methods Procedures A questionnaire assessed in 2 geographically representative national random samples 5000 primary care physicians. In one sample ( N = 2500), obesity defined as a BMI 30 40 kg/m , other > 40. Results Six hundred twenty physicians responded. They rated physical inactivity significantly more important than any cause p <...
A 56-week randomized controlled trial was conducted to evaluate safety and efficacy of a controlled-release combination phentermine topiramate (PHEN/TPM CR) for weight loss (WL) metabolic improvements. Men women with class II III obesity (BMI ≥ 35 kg/m(2)) were placebo, PHEN/TPM CR 3.75/23 mg, or 15/92 added reduced-energy diet. Primary end points percent WL proportions patients achieving 5% WL. Secondary included waist circumference (WC), systolic diastolic blood pressure (BP), fasting...