A5036702554- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- 3D Printing in Biomedical Research
- Pancreatic function and diabetes
- Electrowetting and Microfluidic Technologies
- Dermatologic Treatments and Research
- Acupuncture Treatment Research Studies
- Liver physiology and pathology
- Microfluidic and Bio-sensing Technologies
- Healthcare and Venom Research
- MicroRNA in disease regulation
Sun Yat-sen University
2024-2025
Third Affiliated Hospital of Sun Yat-sen University
2024-2025
Key Laboratory of Guangdong Province
2024
Zhejiang University
2003
Abstract Drug screening based on in-vitro primary tumor cell culture has demonstrated potential in personalized cancer diagnosis. However, the limited number of cells, especially from patients with early stage cancer, hindered widespread application this technique. Hence, we developed a digital microfluidic system for drug using cells and established working protocol precision medicine. Smart control logic was to increase throughput decrease its footprint parallelly screen three drugs 4 × cm...
Split liver transplantation (SLT) has become an indispensable method for expanding the donor pool. However, advanced age in recipients can have significant adverse effects on prognosis. We report case of 82-year-old man with chronic failure and polycystic disease who underwent vivo split right triple lobe October 29, 2021. The patient made a remarkable recovery was discharged 1 month after surgery. To date, he been followed up 32 months, favorable laboratory imaging test results, no...
The shortage of liver grafts compared to recipients necessitates precise organ assessment. This study aimed develop a Machine learning (ML) model predict postoperative delayed graft function (DGF) and visualize the decision-making process for clinical application. Data from 5242 donor-recipient pairs who underwent transplantation (LT) at top 10 transplant centers in China (January 2017 December 2022) were collected. dataset was divided into training validation sets. Sixty-three variables,...
Artificial liver support system (ALSS) has been used to treat hepatic failure and significantly decreased the mortality. TECA hybrid artificial (TECA-HALSS), which combines hollow fiber bioreactor with a plasma exchange circuit, was assess efficacy, safety feasibility in treating severe hepatitis patients. The (HALSS) consists of containing more than 5 ×10 9 porcine hepatocytes device. Fifteen patients were treated this system. All experienced reduction symptoms such as fatigue, abdominal...
Split liver transplantation (SLT) is a procedure where an intact donor splitted into two anatomically and functionally independent grafts, which are transplanted to recipients. SLT can effectively expand the source of liver, has become predominant surgical solution shortage livers after years exploration refinement. History SLT: The development was full twists turns. Before its development, Bismuth Houssin reported pediatric transplantations grafts that had been reduced in size before...
Abstract Background Venous complications after pediatric liver transplantation seriously affect the survival rate of patients and grafts. At present, diagnostic indicators have not been unified. may cause portal hypertension, which lead to splenomegaly splenic vein dilatation. Therefore, changes in spleen be closely related venous complications. The purpose this study was explore relationship between ultrasonic parameters whether these can used for diagnosis Methods We retrospectively...
e14582 Background: Liver transplantation is the most effective treatment for early-stage hepatocellular carcinoma (HCC), but post-transplant recurrence limits efficacy of surgery and affects patient prognosis. Most current attempts to apply immune checkpoint inhibitors (ICIs) posttransplant have resulted in either acute allograft rejection or tumor progression, which may be related disruption balance that maintains tolerance enhances activation. Methods: Therefore, we constructed an...