A5103117547- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Per- and polyfluoroalkyl substances research
- Carcinogens and Genotoxicity Assessment
- Veterinary Medicine and Surgery
- Prenatal Substance Exposure Effects
- Breastfeeding Practices and Influences
- Birth, Development, and Health
- Pharmaceutical studies and practices
- Reproductive Biology and Fertility
- Sperm and Testicular Function
California Department of Toxic Substances Control
2014-2020
California Environmental Protection Agency
2014-2020
University of California, San Francisco
2019-2020
University of Tennessee Health Science Center
2019-2020
Sequoia Foundation
2014-2016
Royal Veterinary College
2006
University of London
2006
We evaluated relationships between persistent organic pollutant (POP) levels in the blood of children with leukemia and POP dust from their household vacuum cleaners. Blood were collected participants California Childhood Leukemia Study at various intervals 1999 to 2007 analyzed for two polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), organochlorine pesticides using gas chromatography–mass spectrometry. Due small sample volumes (100 μL),...
Abstract Prenatal polybrominated diphenyl ether (PBDE) exposures are a public health concern due to their persistence and potential for reproductive developmental harm. However, we have little information about the extent of fetal during critical periods variation in groups that may be more highly exposed, such as communities color lower socioeconomic status (SES). To characterize maternal–fetal PBDE among potentially vulnerable groups, levels were examined largest sample matched maternal...
DDTs in Maternal Early Postpartum Serum Predicts Testosterone, FSH, and Semen Quality Adult Sons: Evidence from the Child Health Development StudiesAbstract Number:2820 Barbara Cohn*, Piera Cirillo, Myrto Petreas, June-Soo Park, Sabrina Crispo Smith, Nickilou Krigbaum, Pam Factor- Litvak Cohn* Public Institute, United States, E-mail Address: [email protected] , Cirillo States Petreas California Environmental Protection Agency, Park Smith Krigbaum Columbia University, AbstractIntroduction:...
Introduction In some cross sectional studies exposure to PCBs is associated with reduced sperm quality; however, only one small study has investigated prenatal exposure. Methods a sample of 195 adult men whose mothers were enrolled in Child Health and Development the 1960s, we measured 15 PCB congeners maternal early postpartum serum relation concentration, motility, morphology ages 39 47. Linear regression was used estimate associations between levels semen parameters, adjusting for...
Abstract Background Polybrominated diphenyl ether (PBDE) exposures have been associated with adverse pregnancy outcomes. A hypothesized mechanism is via alterations in placental development and function. However, we lack biomarkers that can be used as early indicators of maternal/fetal response to PBDE and/or perturbations or Methods To evaluate the relationship between levels during mid-gestation human ( n = 62), immunolocalized three molecules play key roles cytotrophoblast (CTB)...
While the mechanisms and periods of sensitivity remain undefined, in utero exposures to polybrominated diphenyl ethers (PBDEs) may be linked with placenta-mediated pregnancy complications. To define relationship between PBDE exposure placental development, we performed: 1) an evaluation matched samples maternal serum, placenta, fetal liver collected from healthy pregnant women undergoing elective terminations during mid-gestation (n=180; 2014-16); 2) a semi-qualitative characterization...
Abstract Background Polybrominated diphenyl ether (PBDE) exposures have been associated with adverse pregnancy outcomes. A hypothesized mechanism is via alterations in placental development and function. However, we lack biomarkers that can be used as early indicators of maternal/fetal response to PBDE and/or perturbations or Methods To evaluate the relationship between levels during mid-gestation human ( n = 62), immunolocalized three molecules play key roles cytotrophoblast (CTB)...