A5013701686- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Health and Disease Prevention
- Non-Invasive Vital Sign Monitoring
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Blood Pressure and Hypertension Studies
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Renal function and acid-base balance
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiovascular Function and Risk Factors
- Ultrasound in Clinical Applications
- Abdominal Surgery and Complications
- Heart Rate Variability and Autonomic Control
- Pulmonary Hypertension Research and Treatments
- Anesthesia and Sedative Agents
- Veterinary Pharmacology and Anesthesia
- Cardiac pacing and defibrillation studies
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Kidney Injury Research
- Pleural and Pulmonary Diseases
- Pneumothorax, Barotrauma, Emphysema
Hospital Jerez Puerta del Sur
2016-2025
Spanish Society of Hematology and Hemotherapy
2022-2025
Hospital Universitario Puerto Real
2024-2025
Universidad Complutense de Madrid
2024
Edwards Lifesciences (United States)
2022-2023
Hospital Universitario Infanta Leonor
2023
Bellvitge University Hospital
2023
Universitat de Barcelona
2023
Edwards Lifesciences (Switzerland)
2022
Intensive Care Society
2022
Background: Postoperative acute kidney injury (AKI) after major abdominal surgery leads to poor outcomes. The Hypotension Prediction Index (HPI) may aid in managing intraoperative hemodynamic instability. This study assessed if HPI-guided therapy reduces moderate-to-severe AKI incidence moderate-to-high-risk elective patients. Methods: multicenter randomized trial was conducted from October 2022 February 2024 across 28 hospitals evaluating management compared a wide range of real-world...
Hemodynamic resuscitation should be aimed at achieving not only adequate cardiac output but also sufficient mean arterial pressure (MAP) to guarantee tissue perfusion pressure. Since the response volume expansion (VE) depends on tone, knowing whether a patient is preload-dependent provides partial solution problem. The objective of this study was assess ability functional evaluation tone by dynamic elastance (Ea(dyn)), defined as pulse variation (PPV) stroke (SVV) ratio, predict hemodynamic...
Intraoperative hypotension (IOH) is associated with increased morbidity and mortality. Hypotension Prediction Index (HPI) a machine learning derived algorithm that predicts IOH shortly before it occurs. We tested the hypothesis application of HPI in combination pre-defined Goal Directed Therapy (GDT) hemodynamic protocol reduces during major gynaecologic oncologic surgery. enrolled women scheduled for surgery under general anesthesia invasive arterial pressure monitoring. Patients were...
The passive leg-raising (PLR) maneuver provides a dynamic assessment of fluid responsiveness inducing reversible increase in cardiac preload. Since its effects are sudden and transitory, continuous output (CO) monitoring is required to appropriately assess the hemodynamic response PLR. On other hand, changes partial end-tidal CO2 pressure (PETCO2) have been demonstrated be tightly correlated with CO during constant ventilation stable tissue production (VCO2). In this study we tested...
Functional assessment of arterial load by dynamic elastance (Eadyn), defined as the ratio between pulse pressure variation (PPV) and stroke volume (SVV), has recently been shown to predict response expansion (VE) in hypotensive, preload-dependent patients. However, because both SVV PPV were obtained from analysis, a mathematical coupling factor could not be excluded. We therefore designed this study confirm whether Eadyn, two independent signals, allows prediction VE fluid-responsive...
Maximal left ventricular (LV) pressure rise (LV dP/dtmax), a classical marker of LV systolic function, requires catheterization, thus surrogate arterial waveform measures have been proposed. We compared and (femoral radial) dP/dtmax to the slope end-systolic pressure-volume relationship (Ees), load-independent measure contractility, determine interactions between Ees as loading contractility varied. measured data using conductance catheter femoral radial pressures fluid-filled in 10...
In Brief BACKGROUND: Dynamic arterial elastance (Eadyn), defined as the pulse pressure variation (PPV) to stroke volume (SVV) ratio, has been suggested a predictor of response fluid administration. this study, we assessed effectiveness Eadyn predict blood challenge (FC) in preload-dependent, spontaneously breathing patients. METHODS: Patients admitted postoperatively and monitored with Nexfin monitor (BMEYE, Amsterdam, The Netherlands) were enrolled study. included analysis if they had an...
Although several parameters have been proposed to predict the hemodynamic response fluid expansion in critically ill patients, most of them are invasive or require use special monitoring devices. The aim this study is determine whether noninvasive evaluation respiratory variation brachial artery peak velocity flow measured using Doppler ultrasound could responsiveness mechanically ventilated patients.We conducted a prospective clinical research 17-bed multidisciplinary ICU and included 38...
The aim of this study was to quantify the impact different cardiovascular factors on left ventricular ejection fraction (LVEF) and test a novel LVEF calculation considering these factors.10 pigs were studied. experimental protocol consisted sequentially changing afterload, preload contractility. LV pressure-volume (PV) loops peripheral arterial pressure obtained before after each intervention. calculated as stroke volume (SV)/end-diastolic (EDV). We studied global cardiac function variables:...
Dynamic arterial elastance (Eadyn), the ratio between pulse pressure and stroke volume changes during respiration, has been postulated as an index of coupling left ventricle (LV) system. We aimed to confirm this hypothesis using gold-standard for defining LV contractility, afterload, evaluating ventricular-arterial (VA) efficiency different loading contractile experimental conditions. Twelve Yorkshire healthy female pigs submitted three consecutive stages with two opposite interventions...
The reliability of pulse pressure analysis to estimate cardiac output is known be affected by arterial load changes. However, the contribution each aspect could substantially different. In this study, we evaluated agreement eight non-commercial algorithms for estimating (PPCO) with esophageal Doppler (EDCO) during acute changes load. addition, aimed determine optimal parameter that detect a clinically significant difference between PPCO and EDCO. We included mechanically ventilated patients...
Intraoperative hypotension is common and has been associated with adverse events, including acute kidney failure, myocardial infarction, stroke. Since blood pressure a multidimensional measurable variable, artificial intelligence machine learning have used to predict it. To date, studies shown that the prediction prevention of can reduce incidence hypotension. This review describes development evaluation an predictive algorithm called Hypotension Prediction (HPI), which up 15 min before it occurs.