A5078337567- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Cardiovascular Syncope and Autonomic Disorders
- Blood Pressure and Hypertension Studies
- Nausea and vomiting management
- Spine and Intervertebral Disc Pathology
- Non-Invasive Vital Sign Monitoring
- Immune Response and Inflammation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Shoulder Injury and Treatment
- Airway Management and Intubation Techniques
- Bacterial Identification and Susceptibility Testing
- Intensive Care Unit Cognitive Disorders
- Ultrasound in Clinical Applications
- Acute Kidney Injury Research
- RNA and protein synthesis mechanisms
- Biomedical and Chemical Research
- Heart Rate Variability and Autonomic Control
Philipps University of Marburg
2017-2025
Universitätsklinikum Gießen und Marburg
2024-2025
Abstract In 2023, the first German guideline on intraoperative haemodynamic monitoring and management for adults having non-cardiac surgery was published. The aim of this survey to identify how anaesthetists in Germany managed haemodynamics blood pressure before its publication. September October members Society Anaesthesiology Intensive Care Medicine (DGAI) were invited via email participate anonymous online survey. Thirty-one questions covered demographics, clinical experience, approaches...
The 20:1 combination of cafedrine and theodrenaline (C/T) is widely used in Germany for the treatment arterial hypotension. Since there little knowledge about impact covariates on effect, aim was to develop a kinetic/pharmacodynamic covariate model describing mean pressure (MAP), systolic (SBP) diastolic blood (DBP), heart rate (HR) 30 min after administration C/T.
Abstract Background Sympathomimetic drugs are a therapeutic cornerstone for the management of hypotensive states like intraoperative hypotension (IOH). While cafedrine/theodrenaline (C/T) is widely used in Germany to restore blood pressure patients with IOH, more research required compare its effectiveness alternatives such as ephedrine (E) that commonly available internationally. Methods HYPOTENS (NCT02893241, DRKS00010740) was prospective, national, multicenter, open-label, two-armed,...
In the postoperative period, immediate recovery of muscular power is essential for patient safety, but this can be affected by anaesthetic drugs, opioids and neuromuscular blocking agents (NMBA). cohort study, we evaluated patient-related factors contributing to reduced muscle pulse oximetric saturation.We prospectively observed 615 patients scheduled minor surgery. Premedication, general anaesthesia respiratory settings were standardized according standard operating procedures (SOP). If...
Objective: Intraoperative arterial hypotension (IOH) is associated with poor patient outcome. This study aims to compare the hemodynamic effects of Cafedrine/Theodrenaline (C/T) and Noradrenaline (NA) for treatment in patients who develop IOH after anesthesia induction.Research design methods: a national, randomized, parallel-group, multicenter open-label study. Adult (≥ 50 years, ASA-classification III-IV) undergo elective surgery will be included. When (MAP <70 mmHg) develops, C/T or NA...
This article describes the statistical analysis plan for Biomarker-guided intervention to prevent AKI after major surgery (BigpAK-2) trial.